Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amanda P. Struckhoff"'
Autor:
Luis Del Valle, Thersa Sweet, Amanda Parker-Struckhoff, Georgina Perez-Liz, Sergio Piña-Oviedo
Publikováno v:
Viruses, Vol 12, Iss 11, p 1253 (2020)
Progressive Multifocal Leukoencephalopathy (PML) is a fatal demyelinating disease of the CNS, resulting from the lytic infection of oligodendrocytes by the human neurotropic polyomavirus JC (JCPyV), typically associated with severe immunocompromised
Externí odkaz:
https://doaj.org/article/101c846bb57345fb9d9e81e3a3199875
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619476
Cell cultures constitute an important tool for research as a way to reproduce pathological processes in a controlled system. However, the culture of brain-derived cells in monolayer presents significant challenges that obscure the fidelity of in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a23dc6babe0f494b26485afba95c101c
https://doi.org/10.1007/978-1-0716-1948-3_15
https://doi.org/10.1007/978-1-0716-1948-3_15
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85409 (2014)
Epithelial plasticity plays a critical role during physiological processes, such as wound healing and tissue regeneration, and dysregulation of epithelial plasticity can lead to pathological conditions, such as cancer. Cell-cell junctions are a criti
Externí odkaz:
https://doaj.org/article/c8f5e8577197413fbd656d93850750d2
Autor:
Michael J Ripple, Amanda Parker Struckhoff, Jimena Trillo-Tinoco, Li Li, David A Margolin, Robin McGoey, Luis Del Valle
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106257 (2014)
During the last decade, mounting evidence has implicated the human neurotropic virus JC virus in the pathology of colon cancer. However, the mechanisms of JC virus-mediated oncogenesis are still not fully determined. One candidate to mediate these ef
Externí odkaz:
https://doaj.org/article/a4a4c4bfbc42477786daeba81330622e
Autor:
David Nguyen, Rolf Renne, Lu Dai, Jing Qiao, Karlie Bonstaff, Bryan P. Toole, Luis Del Valle, Chris Parsons, Zhiqiang Qin, Amanda P. Struckhoff, Lisa Doyle
Publikováno v:
Oncotarget
Kaposi's Sarcoma-associated Herpesvirus (KSHV) is the etiologic agent of several malignancies, including Kaposi's Sarcoma (KS), which preferentially arise in immunocompromised patients such as HIV+ subpopulation and lack effective therapeutic options
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df0bb3f568210a674167c66cb743ba8
http://europepmc.org/articles/PMC4891132
http://europepmc.org/articles/PMC4891132
Autor:
Francesca Peruzzi, Amanda P. Struckhoff, Luis Del Valle, Piotr Waligórski, Johanna K Ecke, Krzysztof Reiss
Publikováno v:
International Journal of Veterinary Science and Research. 1:008-010
Hemangiosarcoma (HSA) is a common and highly metastatic tumor that affects predominantly large-breed dogs. The median survival time for dogs diagnosed with splenic HSA without adjuvant chemotherapy after surgery is 86 days.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7e344ec9cf90436627eb4e1a500877e
https://doi.org/10.17352/ijvsr.000003
https://doi.org/10.17352/ijvsr.000003
Autor:
Shengli Dong, Prachi Jain, Suresh K. Alahari, Rebecca A. Worthylake, Somesh Baranwal, Amanda P. Struckhoff
Publikováno v:
Journal of Biological Chemistry. 288:15495-15509
Biallelic inactivation of LKB1, a serine/threonine kinase, has been detected in 30% of lung adenocarcinomas, and inhibition of breast tumor growth has been demonstrated. We have identified the tumor suppressor, Nischarin, as a novel binding partner o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41deb794d8c2d1088ae90db04126b50a
https://doi.org/10.1074/jbc.m112.418103
https://doi.org/10.1074/jbc.m112.418103
Autor:
William D. Meacham, Amanda P. Struckhoff, Barbara S. Beckman, Matthew E. Burow, James W. Antoon
Publikováno v:
Experimental Biology and Medicine. 234:1253-1263
An estimated 182,640 women and 1,990 men were diagnosed with breast cancer in 2008, and approximately 40,480 women and 450 men died from the disease ( 1 ). Thus, continued mechanistic studies are needed to understand the causes and develop additional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6687ff0ab378cb560754e12bc9ec78c5
https://doi.org/10.3181/0902-mr-77
https://doi.org/10.3181/0902-mr-77
Autor:
Daniel E. Frigo, Steven Elliott, Barbara S. Beckman, John A. McLachlan, Amanda P. Struckhoff, Matthew E. Burow, Katinka A. Vigh
Publikováno v:
Toxicology Letters. 155:227-238
Some xenobiotics, such as dichlorodiphenyltrichloroethane (DDT), bind to and activate estrogen receptors (ERs), eliciting estrogenic effects in both wildlife and humans. However, our laboratory and others have demonstrated that DDT and DDT-like compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db9db49abe3864fca407607c02f5fa6
https://doi.org/10.1016/j.toxlet.2004.09.008
https://doi.org/10.1016/j.toxlet.2004.09.008
Autor:
Steven Elliott, Amanda P. Struckhoff, Yan Tang, Matthew E. Burow, Timothy G. Hammond, Robert Bittman, Sanda Clejan, Barbara S. Beckman
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 309:523-532
Recent evidence suggests a role for aberrant ceramide levels in the pathogenesis of cancer and chemoresistance and indicates that manipulation of tumor ceramide levels may be a useful strategy in the fight against breast cancer. This study demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c889be13a8cc6897a3157dc22a242ad
https://doi.org/10.1124/jpet.103.062760
https://doi.org/10.1124/jpet.103.062760