Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amanda P. Malefyt"'
Autor:
Uchenna Asogwa, T. Ryan Duckett, Amanda P. Malefyt, Lindsey Stevens, Gale Mentzer, Matthew W. Liberatore
Publikováno v:
Journal of Chemical Education.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::983bb0d6628d8b856bd72c42c0078dc4
https://doi.org/10.1021/acs.jchemed.2c01062
https://doi.org/10.1021/acs.jchemed.2c01062
Autor:
S. Patrick Walton, Joseph A. Gredell, Erin B. Vogel, Amanda P. Malefyt, Christina Chan, R. Chauncey Splichal, Milton R. Smith, Georgina Comiskey
Publikováno v:
Nucleic Acid Ther
The development of delivery vehicles for small interfering RNAs (siRNAs) remains a bottleneck to widespread clinical use. Cationic polymers represent an important class of potential delivery vehicles. In this study, we used alkyne-azide click chemist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cffce87d3ff847a3819bb10ae733c2b
https://pubmed.ncbi.nlm.nih.gov/32749923
https://pubmed.ncbi.nlm.nih.gov/32749923
Autor:
Stephen D. Lindeman, Sean J. Kappes, Ming Wu, Daniel Vocelle, S. Patrick Walton, Amanda P. Malefyt, Christina Chan
Publikováno v:
FEBS Journal. 281:320-330
In the development of RNA interference (RNAi) therapeutics, merely selecting short, interfering RNA (siRNA) sequences that are complementary to the messenger RNA (mRNA) target does not guarantee target silencing. Current algorithms for selecting siRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec3c539a64f4fcd2d45ca0f1a88e8aad
https://doi.org/10.1111/febs.12599
https://doi.org/10.1111/febs.12599
Autor:
Amanda P. Malefyt, Kwasi Adu-Berchie, Christina Chan, Daniel Vocelle, Olivia M. Chesniak, S. Patrick Walton, Georgina Comiskey, Milton R. Smith
Understanding the endocytosis and intracellular trafficking of short interfering RNA (siRNA) delivery vehicle complexes remains a critical bottleneck in designing siRNA delivery vehicles for highly active RNA interference (RNAi)-based therapeutics. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f543baad3919a9b30d61a105bf30cc1
https://europepmc.org/articles/PMC5072529/
https://europepmc.org/articles/PMC5072529/
Publikováno v:
Nano LIFE. 2(3)
The development of nanoscale delivery vehicles for siRNAs is a current topic of considerable importance. However, little is understood about the exact trafficking mechanisms for siRNA-vehicle complexes across the plasma membrane and into the cytoplas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f05250acf1160ebfc4f392dc276723
https://pubmed.ncbi.nlm.nih.gov/23956796
https://pubmed.ncbi.nlm.nih.gov/23956796
Publikováno v:
Regulatory RNAs ISBN: 9783642225161
Current RNA-based therapeutics are principally focused toward activating the RNA interference (RNAi) pathway through exogenous administration of short interfering RNAs (siRNAs) and sometimes short hairpin RNAs (shRNAs). The promise of RNAi-based ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f7dd13d73343477d16d11ae83eec51
https://doi.org/10.1007/978-3-642-22517-8_19
https://doi.org/10.1007/978-3-642-22517-8_19