Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Amanda P Henry"'
Autor:
Bo Liu, Amanda P Henry, Sheyda Azimi, Suzanne Miller, Frank K Lee, Jane C Lee, Kelly Probert, Michael I Kotlikoff, Ian Sayers, Ian P Hall
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221899 (2019)
IntroductionGenome-Wide Association Studies suggest glutathione S transferase C terminal domain (GSTCD) may play a role in development of Chronic Obstructive Pulmonary Disease. We aimed to define the potential role of GSTCD in airway inflammation and
Externí odkaz:
https://doaj.org/article/ec8d27b6cfac44e880f6ab3ddd84cfa7
Autor:
Suzanne Miller, Amanda P Henry, Emily Hodge, Alexander K Kheirallah, Charlotte K Billington, Tracy L Rimington, Sangita K Bhaker, Ma'en Obeidat, Erik Melén, Simon K Merid, Caroline Swan, Catherine Gowland, Carl P Nelson, Ceri E Stewart, Charlotte E Bolton, Iain Kilty, Anders Malarstig, Stuart G Parker, Miriam F Moffatt, Andrew J Wardlaw, Ian P Hall, Ian Sayers
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164041 (2016)
Genome-Wide Association Studies have identified associations between lung function measures and Chronic Obstructive Pulmonary Disease (COPD) and chromosome region 6p21 containing the gene for the Advanced Glycation End Product Receptor (AGER, encodin
Externí odkaz:
https://doaj.org/article/fddddc60e55d4be390faa9c32649f704
Autor:
Ma'en Obeidat, Suzanne Miller, Kelly Probert, Charlotte K Billington, Amanda P Henry, Emily Hodge, Carl P Nelson, Ceri E Stewart, Caroline Swan, Louise V Wain, María Soler Artigas, Erik Melén, Kevin Ushey, Ke Hao, Maxime Lamontagne, Yohan Bossé, Dirkje S Postma, Martin D Tobin, Ian Sayers, Ian P Hall
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74630 (2013)
Genome-Wide Association Study (GWAS) meta-analyses have identified a strong association signal for lung function, which maps to a region on 4q24 containing two oppositely transcribed genes: glutathione S-transferase, C-terminal domain containing (GST
Externí odkaz:
https://doaj.org/article/29ed6b1386194cdc9e6d41e5c57cb629
Autor:
Bjørn Peare Bartholdy, Amanda G. Henry
Publikováno v:
Frontiers in Earth Science, Vol 10 (2022)
Dental calculus has proven to contain a wealth of information on the dietary habits of past populations. These insights have, to a large extent, been obtained by the extraction and identification of starch granules contained within the mineralised de
Externí odkaz:
https://doaj.org/article/4d7cf994af214fb980d74349ebdc14a2
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 22, Iss 1, Pp 1-7 (2021)
Abstract Background Genetic variation has a key role in the development of asthma, but genetic influences may vary between different populations. In this study, we looked for evidence of association of key asthma SNPs, namely, rs1420101 and rs1019215
Externí odkaz:
https://doaj.org/article/9b15df517e014722b18bdd8aba0df0f3
Autor:
Amanda P. Henry, Kelly Probert, Ceri E. Stewart, Dhruma Thakker, Sangita Bhaker, Sheyda Azimi, Ian P. Hall, Ian Sayers
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Genome wide association (GWA) studies have reproducibly identified signals on chromosome 4q24 associated with lung function and COPD. GSTCD (Glutathione S-transferase C-terminal domain containing) represents a candidate causal gene in this l
Externí odkaz:
https://doaj.org/article/45b95aff7d3b48fb89b56781600c8437
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247108 (2021)
In tropical rainforests, access to and availability of natural resources are vital for the dietary diversity and food security of forest-dwelling societies. In the Congo Basin, these are challenged by the increasing exploitation of forests for bushme
Externí odkaz:
https://doaj.org/article/fac70af8174b45d9b29e35992fd9dfc0
Publikováno v:
eLife, Vol 9 (2020)
The human subcortex is comprised of more than 450 individual nuclei which lie deep in the brain. Due to their small size and close proximity, up until now only 7% have been depicted in standard MRI atlases. Thus, the human subcortex can largely be co
Externí odkaz:
https://doaj.org/article/632d2bfc666540f3847ca8ff29c4120f
Autor:
Sangita Bhaker, Michael A. Portelli, Robert J. Hall, David O. Bates, Ian Sayers, Vincent Pang, Amanda P. Henry, Tyson V. Sharp, Jonathan O'Loughlin
Publikováno v:
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 1 (2021)
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 1 (2021)
Genetic studies have identified several epithelial-derived genes associated with airway diseases. However, techniques used to study gene function frequently exceed the proliferative potential of primary human bronchial epithelial cells (HBECs) isolat
Autor:
David O. Bates, Vincent Pang, Judith M. Vonk, Charlote K. Billington, John W. Holloway, Sangita Bhaker, Cornelis J. Vermeulen, Don D. Sin, Ian Sayers, Martin D. Tobin, Peter H. Howarth, F. Nicole Dijk, David C. Nickle, Ian P. Hall, Yohan Bossé, Louise V. Wain, Dominick E. Shaw, John D Blakey, Andrew M. Fogarty, Amisha Singapuri, Michael A. Portelli, Martijn C. Nawijn, Cheng J. Xu, Andrew V. Benest, Ma'en Obeidat, Liam G Heaney, Jenny Hankinson, Maarten van den Berge, Rekha Chaudhuri, Angela Simpson, Tricia M. McKeever, Simon R. Johnson, Adel H. Mansur, Robert Niven, Zara Pogson, Gabrielle A. Lockett, Christopher E. Brightling, Amanda P. Henry, Neil C. Thomson, Nick Shrine, Gerard H. Koppelman, Maria Ketelaar, Alen Faiz
Publikováno v:
Journal of Allergy and Clinical Immunology, 147(1), 144-157. MOSBY-ELSEVIER
Background: Asthma is a complex disease with multiple phenotypes that may differ in disease pathobiology and treatment response. IL33 single nucleotide polymorphisms (SNPs) have been reproducibly associated with asthma. IL33 levels are elevated in sp