Výsledky vyhledávání - "Amanda Niqula"

Akademický článek

Akap5 links synaptic dysfunction to neuroinflammatory signaling in a mouse model of infantile neuronal ceroid lipofuscinosis

Autor: Kevin P. Koster, Zach Fyke, Thu T. A. Nguyen, Amanda Niqula, Lorena Y. Noriega-González, Kevin M. Woolfrey, Mark L. Dell’Acqua, Stephanie M. Cologna, Akira Yoshii

Publikováno v: Frontiers in Synaptic Neuroscience, Vol 16 (2024)

Palmitoylation and depalmitoylation represent dichotomic processes by which a labile posttranslational lipid modification regulates protein trafficking and degradation. The depalmitoylating enzyme, palmitoyl-protein thioesterase 1 (PPT1), is associat

Externí odkaz: https://doaj.org/article/e3a613aeb95d49d588cfd343ac8d71e8

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Loss of Depalmitoylation Exaggerates Synaptic Upscaling and Leads to Neuroinflammation in a Lysosomal Storage Disease

Autor: Kevin P Koster, Eden Flores-Barrera, Emilce Artur de la Villarmois, Thu T. A. Nguyen, Amanda Niqula, Lorena Y Noriega-González, Zach Fyke, Adriana Caballero, Stephanie M. Cologna, Kuei Y. Tseng, Akira Yoshii

SummaryPalmitoylation and depalmitoylation are the dichotomic processes of lipid modification regulating protein trafficking, recycling, and degradation, thereby controlling proteostasis. Despite our understanding of palmitoylation, depalmitoylation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7ee22dfe4f9a25793ca73fba863c1c3
https://doi.org/10.1101/2021.12.16.473002

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