Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amanda Niquette"'
Autor:
Cherrie K. Donawho, David J. Frost, Saul H. Rosenberg, Vincent L. Giranda, Thomas D. Penning, Gui-Dong Zhu, Loren Lasko, Yan Shi, Xuesong Liu, Amanda Niquette, Gail Bukofzer, Paul A. Ellis, Debra Montgomery, Luis E. Rodriguez, Yi-Chun Wang, Joann P. Palma
Supplementary Data from ABT-888 Confers Broad In vivo Activity in Combination with Temozolomide in Diverse Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333c77c5988d9bdf51e7b3f44368218e
https://doi.org/10.1158/1078-0432.22439922.v1
https://doi.org/10.1158/1078-0432.22439922.v1
Autor:
Cherrie K. Donawho, David J. Frost, Saul H. Rosenberg, Vincent L. Giranda, Thomas D. Penning, Gui-Dong Zhu, Loren Lasko, Yan Shi, Xuesong Liu, Amanda Niquette, Gail Bukofzer, Paul A. Ellis, Debra Montgomery, Luis E. Rodriguez, Yi-Chun Wang, Joann P. Palma
Purpose: ABT-888, currently in phase 2 trials, is a potent oral poly(ADP-ribose) polymerase inhibitor that enhances the activity of multiple DNA-damaging agents, including temozolomide (TMZ). We investigated ABT-888+TMZ combination therapy in multipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67613654a79b86ec8f269de75f396056
https://doi.org/10.1158/1078-0432.c.6517308.v1
https://doi.org/10.1158/1078-0432.c.6517308.v1
Autor:
Jennifer J. Bouska, Jianwei Shen, David M. Barnes, Cherrie K. Donawho, Qian Zhang, Jieyi Wang, Randy L. Bell, Yi-Chun Wang, Amanda Niquette, Lora A. Tucker, Jonathan A. Meulbroek, George S. Sheppard, Jason Stavropoulos, Gail Bukofzer
Publikováno v:
Proceedings of the National Academy of Sciences. 105:1838-1843
This laboratory and others have shown that agents that inhibit the in vitro catalytic activity of methionine aminopeptidase-2 (MetAP2) are effective in blocking angiogenesis and tumor growth in preclinical models. However, these prototype MetAP2 inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d604e4a3dccec4014cd3857f6f044b6
https://doi.org/10.1073/pnas.0708766105
https://doi.org/10.1073/pnas.0708766105
Autor:
Paul Ellis, Luis E. Rodriguez, Gui-Dong Zhu, David Frost, Loren M. Lasko, Gail Bukofzer, Yan Shi, Joann P. Palma, Vincent L. Giranda, Cherrie K. Donawho, Debra Montgomery, Xuesong Liu, Saul H. Rosenberg, Amanda Niquette, Thomas D. Penning, Yi-Chun Wang
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 15(23)
Purpose: ABT-888, currently in phase 2 trials, is a potent oral poly(ADP-ribose) polymerase inhibitor that enhances the activity of multiple DNA-damaging agents, including temozolomide (TMZ). We investigated ABT-888+TMZ combination therapy in multipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cca6471aaaf8b2a5445644e037d8ca4
https://pubmed.ncbi.nlm.nih.gov/19934293
https://pubmed.ncbi.nlm.nih.gov/19934293
Autor:
Nayereh S. Ghoreishi-Haack, Junling Li, Baole Wang, J. Owen McCall, Steven K. Davidsen, Lori J. Pease, Paul Tapang, Daniel H. Albert, Yi-Chun Wang, Nirupama B. Soni, Peter F. Bousquet, Amanda Niquette, David R. Reuter, Cherrie K. Donawho, Patrick A. Marcotte, Yanping Luo, Kresna Hartandi, Eric F. Johnson, Gail Bukofzer, Jason Stavropoulos, Jun Guo, Michael R. Michaelides, Jennifer J. Bouska, Terrance J. Magoc, Ru-Qi Wei, Keith B. Glaser, Yujia Dai
Publikováno v:
Molecular cancer therapeutics. 5(4)
ABT-869 is a structurally novel, receptor tyrosine kinase (RTK) inhibitor that is a potent inhibitor of members of the vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptor families (e.g., KDR IC50 = 4 nmol/L) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb38d2236e55542477a01ad526a84c9a
https://pubmed.ncbi.nlm.nih.gov/16648571
https://pubmed.ncbi.nlm.nih.gov/16648571
Autor:
Luis E. Rodriguez, Keith B. Glaser, Paul Tapang, Patrick A. Marcotte, Jun Guo, Michael R. Michaelides, Omar Jameel Shah, Amanda Niquette, Robin Heyman, Cherrie K. Donawho, Robin R. Frey, Chris Tse, Daniel H. Albert, Mark G. Anderson, Michael L. Curtin, Joann P. Palma, Jennifer J. Bouska
Publikováno v:
Cancer Research. 72:1818-1818
The Aurora kinases (Aurora A, B, and C) play essential roles in regulating cell division in mammalian cells and their over-expression in diverse tumor types makes them appealing oncology targets. ABT-348 is a novel, ATP-competitive, multi-targeted ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b42971aea009a1392da3b4aa2b3184f
https://doi.org/10.1158/1538-7445.am2012-1818
https://doi.org/10.1158/1538-7445.am2012-1818