Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Amanda N. Farrugia"'
Autor:
Stephen Fitter, L. Bik To, Andrew C.W. Zannettino, Kate Vandyke, Amanda N. Farrugia, Timothy P. Hughes, AL Dewar
Publikováno v:
Leukemia. 23:994-997
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ffdd21d971bce2b10b7e790619abb5
https://doi.org/10.1038/leu.2008.356
https://doi.org/10.1038/leu.2008.356
Autor:
Panagiota Kostakis, David R. Haynes, C.A. Holding, Gerald J. Atkins, P. Diamond, Jennifer R. Gamble, David M. Findlay, L.B. To, Andrew C.W. Zannettino, Amanda N. Farrugia
Publikováno v:
Journal of Cellular Physiology. 204:714-723
Recent studies demonstrate roles for osteoprotegerin (OPG) in both skeletal and extra-skeletal tissues. Although its role in preventing osteoclast (OC) formation and activity is well documented, emerging evidence suggests a role of OPG in endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883c43fc18b13b23cd6d6b69d194116e
https://doi.org/10.1002/jcp.20354
https://doi.org/10.1002/jcp.20354
Autor:
Luen Bik To, Kevin Lynch, Amanda N. Farrugia, Beiqing Pan, Jonathan Green, Gerald J. Atkins, Andreas Evdokiou, Andrew C.W. Zannettino, David M. Findlay, Stan Gronthos
Publikováno v:
Bone. 34:112-123
Previous studies have attributed the increase in bone mass observed following bisphophonate (BP) therapy to their effects on bone-resorbing osteoclasts (OCs). However, recent evidence suggests that BPs can also act directly on bone forming osteoblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5ba16b435d2c40fc0736d9fddf7b9a
https://doi.org/10.1016/j.bone.2003.08.013
https://doi.org/10.1016/j.bone.2003.08.013
Autor:
Amanda N. Farrugia, Andreas Evdokiou, Gerald J. Atkins, Andrew C.W. Zannettino, Stan Gronthos, Kate Harrison, Beiqing Pan, Panagiota Kostakis, David M. Findlay
Publikováno v:
Journal of Bone and Mineral Research. 18:1088-1098
Human osteoblast phenotypes that support osteoclast differentiation and bone formation are not well characterized. Osteoblast differentiation markers were examined in relation to RANKL expression. RANKL expression was induced preferentially in immatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687f148bc5b789fc6936493b9b5c5000
https://doi.org/10.1359/jbmr.2003.18.6.1088
https://doi.org/10.1359/jbmr.2003.18.6.1088
Autor:
Amanda N. Farrugia, Nobutaka Fujii, Stan Gronthos, L. Bik To, Andrew C.W. Zannettino, Andreas Evdokiou, Sally Martin, Agatha Labrinidis, Peter D. O’Loughlin, Peter Diamond
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 24(7)
The plasma cell (PC) malignancy, multiple myeloma (MM), is unique among hematological malignancies in its capacity to cause osteoclast (OC)-mediated skeletal destruction. We have previously shown that elevated plasma levels of PC-derived CXCL12 are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085eb05ca2302ee2564c7049ca8223dc
https://pubmed.ncbi.nlm.nih.gov/19335218
https://pubmed.ncbi.nlm.nih.gov/19335218
Autor:
Sally Martin, Stan Gronthos, AL Dewar, L. Bik To, Andrew C.W. Zannettino, Amanda N. Farrugia, Noemi Horvath
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 12(23)
Purpose: Multiple myeloma is an incurable hematologic malignancy characterized by increased bone marrow angiogenesis and extensive lytic bone disease. We have previously shown that elevated levels of stromal-derived factor-1α (SDF-1α) in peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c7fccb6209f94c89f39f08309d0586
https://pubmed.ncbi.nlm.nih.gov/17145816
https://pubmed.ncbi.nlm.nih.gov/17145816
Autor:
Jeffrey P Houchins, Cristina Vincent, David M. Findlay, Panagiota Kostakis, Andreas Evdokiou, Gerald J. Atkins, Andrew C.W. Zannettino, Amanda N. Farrugia
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 21(9)
RANK expression in vivo on hematopoietic subsets including pre-osteoclasts, identified by monoclonal antibodies, has not been described. We describe the lineages that express RANK in bone marrow, peripheral blood, and GCTs. We show that CD14+RANKhigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fcba158ad2d6b9675ca34986f4c43e
https://pubmed.ncbi.nlm.nih.gov/16939392
https://pubmed.ncbi.nlm.nih.gov/16939392
Autor:
Mark R. Condina, AL Dewar, Barrie Vernon-Roberts, L. Bik To, Amanda N. Farrugia, Andrew C.W. Zannettino, Timothy P. Hughes
Osteoclasts (OCs) are large multinucleated cells derived from progenitor cells of the monocyte-macrophage lineage. Signal transduction via the macrophage–colony-stimulating factor (M-CSF) receptor, c-fms, is essential for OC formation. Since we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1b47aaac82ca2e70cb8d9461c1c3e7
https://hdl.handle.net/11541.2/129996
https://hdl.handle.net/11541.2/129996
Publikováno v:
Methods in molecular medicine. 113
Much of the morbidity and mortality associated with the plasma cell (PC) malignancy, multiple myeloma (MM), is owing to the severe osteolytic bone disease seen in patients with this disease. Although the molecular mechanisms responsible for osteolysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a46e5218b2f813704965bdb0290c378
https://pubmed.ncbi.nlm.nih.gov/15968108
https://pubmed.ncbi.nlm.nih.gov/15968108
Much of the morbidity and mortality associated with the plasma cell (PC) malignancy, multiple myeloma (MM), is owing to the severe osteolytic bone disease seen in patients with this disease. Although the molecular mechanisms responsible for osteolysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ece5873e7e2d06fa0509f03920b6dee
https://doi.org/10.1385/1-59259-916-8:245
https://doi.org/10.1385/1-59259-916-8:245