Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Amanda Maree Walmsley"'
Autor:
David R. Thomas, Amanda Maree Walmsley
Publikováno v:
Prospects of Plant-Based Vaccines in Veterinary Medicine ISBN: 9783319901367
Newcastle disease is a word-wide, highly problematic, infectious, acute respiratory disease of domesticated and wild avian species. Newcastle disease virus proved an ideal target for a proof-of-concept study investigating the ability of a plant-made
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c405d31da659d285c0ca90bc4013c22
https://doi.org/10.1007/978-3-319-90137-4_6
https://doi.org/10.1007/978-3-319-90137-4_6
Autor:
Maria Manuela Rigano, Luigi Frusciante, Giorgio De Guzman, Amanda Maree Walmsley, Amalia Barone
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 2753-2773 (2013)
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 2753-2773 (2013)
The benefits of increased safety and cost-effectiveness make vegetable crops appropriate systems for the production and delivery of pharmaceutical proteins. In particular, Solanaceae edible crops could be inexpensive biofactories for oral vaccines an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a364c8b19aa2c116fb02c6543a9c1459
http://europepmc.org/articles/PMC3588013
http://europepmc.org/articles/PMC3588013
Publikováno v:
Biotechnology Advances. 30:440-448
As commercial approval of the first, purified, plant-based biopharmaceuticals for parenteral delivery to humans approaches, improved strategies for delivery of plant-made vaccines and therapeutics are required to ensure their further development and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42125f94c6c96cc0ac4b0eaff4f7a1f0
https://doi.org/10.1016/j.biotechadv.2011.07.018
https://doi.org/10.1016/j.biotechadv.2011.07.018
Publikováno v:
Biotechnology Letters. 34:1143-1150
The wound-inducible quinolinate phosphoribosyl transferase promoter from Nicotiana tabacum (NtQPT2) was assessed for its capacity to produce B-subunit of the heat-labile toxin (LTB) from enterotoxigenic Escherichia coli in transgenic plant tissues. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d5ac4a2194a8638fb25b6b3baefdc4
https://doi.org/10.1007/s10529-012-0879-6
https://doi.org/10.1007/s10529-012-0879-6
Autor:
Amanda Maree Walmsley, Robert Shepherd, John D. Hamill, Giorgio De Guzman, Assunta Pelosi, Elza Nicole Theresia Meeusen, Gordon Drummond Sanson
Publikováno v:
Current Drug Delivery. 8:612-621
This study investigated the site of release of a model vaccine antigen from plant cells and the corresponding induced immune response. Three plant tissues (leaf, fruit and hairy root) and two formulations (aqueous and lipid) were compared in two mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907c82e3e9a4b9b9ee53feb06dee245d
https://doi.org/10.2174/156720111797635513
https://doi.org/10.2174/156720111797635513
Autor:
Amanda Maree Walmsley, Sandra J. Gendler, Hugh S. Mason, M. Lucrecia Alvarez, Josephine Grass, Pinku Mukherjee, Maria Manuela Rigano, Julia Pinkhasov, Khanrat Piensook, Dalia Larios, Martin Pabst
Publikováno v:
Plant Biotechnology Journal. 9:991-1001
Summary The human epithelial mucin MUC1 is a heavily glycosylated transmembrane protein that is overexpressed and aberrantly glycosylated on over 90% of human breast cancers. The altered glycosylation of MUC1 reveals an immunodominant peptide along i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3258606827cd8eeb44cb50726e43e0ab
https://doi.org/10.1111/j.1467-7652.2011.00614.x
https://doi.org/10.1111/j.1467-7652.2011.00614.x
Publikováno v:
International Journal of Molecular Sciences
The science and policy of pharmaceuticals produced and/or delivered by plants has evolved over the past twenty-one years from a backyard remedy to regulated, purified products. After seemingly frozen at Phase I human clinical trials with six orally d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f23465cb9ba419e6e8cd4803b368b1b
https://doi.org/10.3390/ijms12053220
https://doi.org/10.3390/ijms12053220
Autor:
Amanda Maree Walmsley, M. Lucrecia Alvarez, Sandra J. Gendler, Hugh S. Mason, Julia Pinkhasov, Pinku Mukherjee, Teresa L. Tinder, Latha B. Pathangey
Publikováno v:
Cancer Immunology, Immunotherapy. 59:1801-1811
Since epithelial mucin 1 (MUC1) is associated with several adenocarcinomas at the mucosal sites, it is pertinent to test the efficacy of a mucosally targeted vaccine formulation. The B subunit of the Vibrio cholerae cholera toxin (CTB) has great pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d3f96ec682e1c058ceba96b6cd5aa5
https://doi.org/10.1007/s00262-010-0906-1
https://doi.org/10.1007/s00262-010-0906-1
Autor:
Jason D Crisantes, Amanda Maree Walmsley, Guy A. Cardineau, Hugh S. Mason, Maria Manuela Rigano, Julia Pinkhasov, Heidi L. Pinyerd, M. Lucrecia Alvarez
Publikováno v:
Vaccine. 24:2477-2490
Yersinia pestis, the causative agent of plague, is an extremely virulent bacterium but there are no approved vaccines for protection against it. Our goal was to produce a vaccine that would address: ease of delivery, mucosal efficacy, safety, rapid s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44d4601f7b3c2d575f9093cbd721328
https://doi.org/10.1016/j.vaccine.2005.12.057
https://doi.org/10.1016/j.vaccine.2005.12.057
Publikováno v:
Transgenic Research
The production of vaccines in transgenic plants was first proposed in 1990 however no product has yet reached commercialization. There are several risks during the production and delivery stages of this technology, with potential impact on the enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcaa22a5843ccb630376939aa6454e1
https://doi.org/10.1007/s11248-005-5697-3
https://doi.org/10.1007/s11248-005-5697-3