Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Amanda M. Schmidt"'
Autor:
Amanda M Schmidt Paustian, Jesus Paez-Cortez, Shaughn Bryant, Susan Westmoreland, Wendy Waegell, Gillian Kingsbury
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182841 (2017)
Mutations in the Interleukin (IL)-23/IL-23 receptor loci are associated with increased inflammatory bowel disease (IBD) susceptibility, and IL-23 neutralization has shown efficacy in early clinical trials. To better understand how an excess of IL-23
Externí odkaz:
https://doaj.org/article/fd68a1fba62c4d07abb5ab434c7ad926
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92888 (2014)
Regulatory T cells (Treg)s attenuate excessive immune responses, making their expansion beneficial in immune-mediated diseases including allogeneic bone marrow transplantation (BMT)-associated graft-versus-host disease (GVHD). We have recently report
Externí odkaz:
https://doaj.org/article/659fe0b75c9144a9adcfa912e46ce889
Autor:
Paustian, Amanda M. Schmidt1 amanda.paustian@abbvie.com, Paez-Cortez, Jesus1, Bryant, Shaughn1, Westmoreland, Susan1, Waegell, Wendy1, Kingsbury, Gillian1
Publikováno v:
PLoS ONE. 8/8/2017, Vol. 12 Issue 8, p1-12. 12p.
Autor:
Taku Kambayashi, Amanda M. Schmidt, Krishna Moody, Ann Marshak-Rothstein, Nathaniel M. Green, Michael A. Oropallo, William Stohl, Vishal J. Sindhava, Stephanie Dorta-Estremera, Lauren E. Higdon, Martin S. Naradikian, Kerstin Nündel, Arpita Myles, Lin Zhou, Michael P. Cancro, Wei Cao
Publikováno v:
Journal of Clinical Investigation. 127:1651-1663
Mature B cell pools retain a substantial proportion of polyreactive and self-reactive clonotypes, suggesting that activation checkpoints exist to reduce the initiation of autoreactive B cell responses. Here, we have described a relationship among the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ddb47a94234450ee2cfe5a7597ab0a
https://doi.org/10.1172/jci89931
https://doi.org/10.1172/jci89931
Autor:
Nadan Wang, Matthew J. Riese, Wen Lu, Xinzhong Dong, Taku Kambayashi, Angela Franciska Haczku, Amanda M. Schmidt Paustian, Reynold A. Panettieri, Sara S. Killingbeck, Moyar Q. Ge, Cameron H. Flayer, Deepak A. Deshpande, Brenal K. Singh, Cynthia J. Koziol-White
Publikováno v:
Science signaling, vol 12, iss 597
Asthma is a chronic allergic inflammatory airway disease caused by aberrant immune responses to inhaled allergens, which leads to airway hyperresponsiveness (AHR) to contractile stimuli and airway obstruction. Blocking T helper 2 (T(H)2) differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40132800d3f05aa38ef8753b334e9de
https://pubmed.ncbi.nlm.nih.gov/31481522
https://pubmed.ncbi.nlm.nih.gov/31481522
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Susan V. Westmoreland, Jesus Paez-Cortez, Gillian Kingsbury, Wendy Waegell, Bryant Shaughn H, Amanda M. Schmidt Paustian
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0182841 (2017)
PLoS ONE, Vol 12, Iss 8, p e0182841 (2017)
Mutations in the Interleukin (IL)-23/IL-23 receptor loci are associated with increased inflammatory bowel disease (IBD) susceptibility, and IL-23 neutralization has shown efficacy in early clinical trials. To better understand how an excess of IL-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7df68e5538ae78bd31d703e5d944550
http://europepmc.org/articles/PMC5549730
http://europepmc.org/articles/PMC5549730
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(3)
Enhancement of NK cell function could be beneficial in treatment of a variety of tumors and infections. However, efforts to improve NK cell function by disrupting negative regulators that target proximal signaling pathways paradoxically results in hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c42ca2def069f13d750a45f11078398
https://pubmed.ncbi.nlm.nih.gov/27342844
https://pubmed.ncbi.nlm.nih.gov/27342844
Autor:
Michael A. Farrar, Evann Corbo-Rodgers, Atsushi Satake, Jonathan S. Maltzman, Amanda M. Schmidt, Taku Kambayashi, Tao Zou
Publikováno v:
The Journal of Immunology. 189:28-32
To ensure immune tolerance, regulatory T cell (Treg) numbers must be maintained by cell division. This process has been thought to be strictly dependent on the Treg TCR interacting with MHC class II. In this study, we report that Treg division does n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d285655867f7a4056d8a981712ec104f
https://doi.org/10.4049/jimmunol.1200507
https://doi.org/10.4049/jimmunol.1200507
Autor:
Matthew J. Riese, Taku Kambayashi, Jonathan S. Maltzman, Yanping Huang, Janis K. Burkhardt, Martha S. Jordan, Vishal J. Sindhava, Amanda M. Schmidt, Enjun Yang, Wen Lu
Regulatory T cells (Tregs) are a subset of CD4+ T cells that maintain immune tolerance in part by their ability to inhibit the proliferation of conventional CD4+ T cells (Tconvs). The role of the TCR and the downstream signaling pathways required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cc57fdc4ae3b8e1fd763da830523f0
https://europepmc.org/articles/PMC4402269/
https://europepmc.org/articles/PMC4402269/
