Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Amanda M. Lulu"'
4
Characteristics of Immune Memory and Effector Activity to Cancer-Expressed MHC Class I Phosphopeptides Differ in Healthy Donors and Ovarian Cancer Patients
Autor: Kimberly A. Chianese-Bullock, Craig L. Slingluff, Susan C. Modesitt, Victor H. Engelhard, Kara L. Cummings, Rachel M Lacy, Paisley T. Myers, Erin D. Jeffery, Amanda M. Lulu, Dennis J. Underwood
Publikováno v: Cancer Immunol Res
Elevated immunity to cancer-expressed antigens can be detected in people with no history of cancer and may contribute to cancer prevention. We have previously reported that MHC-restricted phosphopeptides are cancer-expressed antigens and targets of i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568456df062222c73c9b62c84e07a1af
https://doi.org/10.1158/2326-6066.cir-21-0111
Zobrazit plný text záznamu
5
MHC-restricted phosphopeptide antigens: preclinical validation and first-in-humans clinical trial in participants with high-risk melanoma
Autor: Rebecca C. Obeng, Nikole Varhegyi, Kimberly A. Chianese-Bullock, Gina R. Petroni, Geoffrey R. Weiss, Elizabeth M. Gaughan, Angela L. Ambakhutwala, Emily H. Hall, Kelly T. Smith, Mark Cobbold, Victor H. Engelhard, Kara L. Cummings, Amanda M. Lulu, Paisley T. Myers, Mark E. Smolkin, Nico Buettner, Craig L. Slingluff, Jeffrey Shabanowitz, Kathleen Haden, Donald F. Hunt, Keira E. Mahoney
Publikováno v: Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundPhosphorylated peptides presented by MHC molecules represent a new class of neoantigens expressed on cancer cells and recognized by CD8 T-cells. These peptides are promising targets for cancer immunotherapy. Previous work identified an HLA-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05b415bd0fbb1789a5f1dfcf186652f
https://doi.org/10.1136/jitc-2019-000262
Zobrazit plný text záznamu
6
Evidence of ongoing immune surveillance to cancer-associated phosphopeptides in healthy individuals
Autor: Amanda M Lulu, Kara L. Cummings, Victor H. Engelhard
Publikováno v: The Journal of Immunology. 204:242.54-242.54
Dysregulated protein phosphorylation plays a major role in cancer cell malignancy. We showed that phosphopeptides are presented by MHC-I molecules, representing a new class of cancer neoantigens. We found that healthy donors with no evident prior can
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::368cad6f6ee85046a880649c4836cec0
https://doi.org/10.4049/jimmunol.204.supp.242.54
Zobrazit plný text záznamu
7
Abstract B68: Pre-existing immune memory to cancer-associated phosphopeptides in healthy donors
Autor: Amanda M. Lulu, Victor H. Engelhard, Kara L. Cummings
Publikováno v: Cancer Immunology Research. 8:B68-B68
Identifying appropriate antigens is essential to developing effective cancer vaccines. Protein phosphorylation plays a major role in signal transduction pathways that are dysregulated and contribute to the malignant phenotype of cancer cells. Our lab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0474857a74081937817a14fd9a220769
https://doi.org/10.1158/2326-6074.tumimm18-b68
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje