Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amanda M. DiBattista"'
Publikováno v:
GeroScience
Publikováno v:
Experimental Neurology. 280:97-105
Background Over 70 million Americans inherit the strongest genetic risk factor for Alzheimer's disease (AD), apolipoprotein E4 ( APOE4 ), but have no course for reducing their risk. The association of non-steroidal anti-inflammatory drug (NSAID) use
Autor:
Jessica Jacobs, James H. Howard, G. William Rebeck, Wesley A. Horton, Sikoya Ashburn, Amanda M. DiBattista, Kyle F. Shattuck, Raymond Scott Turner, Xiong Jiang
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
R. Scott Turner, Monica Wei, Victor W. Pike, Kimberly J. Jenko, Joseph Snow, G. William Rebeck, Robert B. Innis, Chul Hyoung Lyoo, William C. Kreisl, Amanda M. DiBattista, Sami S. Zoghbi, Cheryl L. Morse, Jeih-San Liow
Publikováno v:
Alzheimer's & Dementia. 11
Publikováno v:
Alzheimer's & Dementia. 11
Publikováno v:
Frontiers in Human Neuroscience
Frontiers in Human Neuroscience, Vol 8 (2014)
Frontiers in Human Neuroscience, Vol 8 (2014)
Alzheimer’s disease (AD) risk genes alter brain structure and function decades before disease onset. Apolipoprotein E (APOE) is the strongest known genetic risk factor for AD, and a related gene, apolipoprotein J (APOJ), also affects disease risk.
Autor:
Guojun Bu, Sonya B. Dumanis, Hyang Sook Hoe, Edwin J. Weeber, Jung Min Song, G. William Rebeck, Amanda M. DiBattista
Publikováno v:
Biochimica et biophysica acta. 1853(5)
Very Low Density Lipoprotein Receptor (VLDLR) is an apolipoprotein E receptor involved in synaptic plasticity, learning, and memory. However, it is unknown how VLDLR can regulate synaptic and cognitive function. In the present study, we found that VL
Autor:
Robert Padilla, Colin G. DeYoung, Jeremy R. Gray, G. William Rebeck, Timothy R. Mhyre, Amanda M. DiBattista, Adam E. Green
A recent history of failed clinical trials suggests that waiting until even the early stages of onset of Alzheimer's disease may be too late for effective treatment, pointing to the importance of early intervention in young people. Early intervention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e57bcb532b9d07da659ec5852775639
https://europepmc.org/articles/PMC4420146/
https://europepmc.org/articles/PMC4420146/
Publikováno v:
Neuropsychologia. 61
Identifying pathways by which genetic Alzheimer׳s disease (AD) risk factors exert neurocognitive effects in young adults are essential for the effort to develop early interventions to forestall or prevent AD onset. Here, in a brain-imaging cohort of
Autor:
Daniel T.S. Pak, R. Scott Turner, Hey Kyoung Lee, You Me Sung, Jung Min Song, Joo Myung Ahn, Amanda M. DiBattista, Hyang Sook Hoe, Jerry Yang
Publikováno v:
Experimental neurology, vol 252
Song, JM; DiBattista, AM; Sung, YM; Ahn, JM; Turner, RS; Yang, J; et al.(2014). A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease. Experimental Neurology, 252, 105-113. doi: 10.1016/j.expneurol.2013.11.023. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6p46872v
Song, JM; DiBattista, AM; Sung, YM; Ahn, JM; Turner, RS; Yang, J; et al.(2014). A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease. Experimental Neurology, 252, 105-113. doi: 10.1016/j.expneurol.2013.11.023. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6p46872v
We recently reported that the tetra(ethylene glycol) derivative of benzothiazole aniline, BTA-EG4, acts as an amyloid-binding small molecule that promotes dendritic spine density and cognitive function in wild-type mice. This raised the possibility t