Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Amanda M. Cruz"'
Autor:
Roderick Bronson, Arjun Bhutkar, Peter MK Westcott, Francesc Muyas, Haley Hauck, Olivia C Smith, Nathan Sacks, Zack Ely, Alex M Jaeger, William Rideout, Daniel D Zhang, Mary Clare Beytagh, David Canner, Santiago Naranjo, Abbey Jin, Justin Patten, Amanda M Cruz, Sean-Luc Shanahan, Isidro Cortes-Ciriano, Tyler Jacks
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f7ec3338903e4e67abbdc5790810ff7e
Autor:
Jason M. Schenkel, Sara Z. Tavana, Michelle Hillman, Peter M. K. Westcott, Megan L. Burger, Sarah E. Blatt, Tyler Jacks, David Canner, Marta M. Holovatska, Michael Manos, Giorgio Gaglia, Izumi de los Rios Kobara, Aviv Regev, Alex M. Jaeger, Arjun Bhutkar, Sandro Santagata, William L. Hwang, F. Stephen Hodi, Cecily C. Ritch, Amanda M. Cruz, Tamina Kienka, Andrea Garmilla, Alexia L. Barandiaran, Amy Li, Grace E. Crossland
Publikováno v:
Cell
Summary CD8 T cell responses against different tumor neoantigens occur simultaneously, yet little is known about the interplay between responses and its impact on T cell function and tumor control. In mouse lung adenocarcinoma, we found that immunodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881da5a74e035825ca947128bb7a8b0b
https://europepmc.org/articles/PMC8522630/
https://europepmc.org/articles/PMC8522630/
Autor:
Alex M. Jaeger, David Canner, Mary Clare Beytagh, JJ Patten, William M. Rideout, Haley Hauck, Isidro Cortes-Ciriano, Santiago Naranjo, Abbey Jin, Zackery A. Ely, Tyler Jacks, Nathan J. Sacks, Roderick T. Bronson, Peter M. K. Westcott, Francesc Muyas, Arjun Bhutkar, Olivia Smith, Daniel Zhang, Amanda M. Cruz
DNA mismatch repair deficiency (MMRd) is associated with high tumor mutational burden (TMB), increased T cell infiltration, and remarkable responsiveness to immune checkpoint blockade (ICB) therapy1. Nevertheless, about half of MMRd tumors do not res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f615eadc4d03bce6cde32dfce858f582
https://doi.org/10.21203/rs.3.rs-879464/v1
https://doi.org/10.21203/rs.3.rs-879464/v1
Autor:
Alex M. Jaeger, Zackery A. Ely, Peter M. K. Westcott, Amanda M. Cruz, David Canner, Francesc Muyas, Mary Clare Beytagh, JJ Patten, Isidro Cortes-Ciriano, Haley Hauck, Abbey Jin, Roderick T. Bronson, Santiago Naranjo, Daniel Zhang, William M. Rideout, Tyler Jacks, Arjun Bhutkar, Nathan J. Sacks, Olivia Smith
DNA mismatch repair deficiency (MMRd) in human cancer is associated with high tumor mutational burden (TMB), frameshift mutation-derived neoantigens, increased T cell infiltration, and remarkable responsiveness to immune checkpoint blockade (ICB) the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa7b8c8cec8f49449a9abd0ac0e96334
https://doi.org/10.1101/2021.08.24.457572
https://doi.org/10.1101/2021.08.24.457572
Autor:
Sarah E. Blatt, Izumi de los Rios Kobara, Aviv Regev, Arjun Bhutkar, David Canner, Sandro Santagata, Sara Z. Tavana, Amy Li, Jason M. Schenkel, Tyler Jacks, Grace E. Crossland, Michelle Hillman, Tamina Kienka, Peter M. K. Westcott, Andrea Garmilla, Giorgio Gaglia, William L. Hwang, Megan L. Burger, Cecily C. Ritch, Amanda M. Cruz
Publikováno v:
SSRN Electronic Journal.
CD8 T cell responses against different tumor neoantigens occur simultaneously, yet little is known about their interplay and its impact on T cell function and tumor control. In mouse lung adenocarcinoma, we find that immunodominance is established in
Autor:
Peter M. K. Westcott, Francesc M. Remolar, Olivia Smith, Haley Hauck, Nathan J. Sacks, Zackery A. Ely, Alex M. Jaeger, William M. Rideout, Arjun Bhutkar, Daniel Zhang, Mary C. Beytagh, Roderick T. Bronson, David A. Canner, Santiago Naranjo, Abbey Jin, J. J. Patten, Amanda M. Cruz, Isidro Cortes-Ciriano, Tyler Jacks
Publikováno v:
Cancer Immunology Research. 10:P023-P023
Deficient DNA mismatch repair (dMMR) in human cancer is associated with high tumor mutation burden (TMB), frameshift mutation-derived neoantigens, increased T cell infiltration, and remarkable responsiveness to immune checkpoint blockade (ICB) therap
Autor:
Megan L. Burger, Amanda M. Cruz, Grace E. Crossland, Giorgio Gaglia, Cecily C. Ritch, Sarah E. Blatt, Arjun Bhutkar, Sara Z. Tavana, Sandro Santagata, Tyler Jacks
Publikováno v:
Cancer Immunology Research. 10:P010-P010
CD8 T cell responses against different tumor neoantigens occur simultaneously, yet it is unclear whether they interact to potentiate or antagonize the overall anti-tumor response. In a genetically engineered mouse model of lung adenocarcinoma, we fin
Autor:
Peter M. K. Westcott, Abbey Jin, Mary Clare Beytagh, Amanda M. Cruz, Tyler Jacks, Olivia Smith
Publikováno v:
Cancer Research. 78:4091-4091
Human colorectal cancer (CRC) is characterized by a high burden of somatic mutations, particularly in tumors harboring defects in the DNA mismatch repair (MMR) pathway. However, genetically-engineered mouse models (GEMMs) of cancer to date harbor a v
Autor:
Amanda M. Cruz, Christopher J. Ferguson, Daniel Martinez, Diana E. Ferguson, Stephanie M. Rueda
Publikováno v:
European Psychologist. 15:304-311
Despite several studies investigating the impact of sex and violence in television on consumer behavior and memory for products in commercials, results remain inconsistent and debated. The purpose of the current study was to examine the effects of te
Autor:
Diana E. Ferguson, Charles Negy, Stephanie M. Rueda, Daniel Martinez, Amanda M. Cruz, Christopher J. Ferguson
Publikováno v:
Journal of Aggression, Maltreatment & Trauma. 17:395-414
Debate remains regarding the interaction between predictor variables for aggression, including family environment, media violence, and personality. The current study examined the contributions of gender and personality, exposure to physical abuse and