Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Amanda M. Clark"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7133 (2024)
Breast cancer is most common in women, and in most cases there is no evidence of spread and the primary tumor is removed, resulting in a ‘cure’. However, in 10% to 30% of these women, distant metastases recur after years to decades. This is due t
Externí odkaz:
https://doaj.org/article/c73600a59224404abd6d7ce982383ffc
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Interferon-γ (IFNγ) is a cytokine with limited evidence of benefit in cancer clinical trials to date. However, it could potentially play a role in potentiating anti-tumor immunity in the immunologically "cold" metastatic castration-resista
Externí odkaz:
https://doaj.org/article/f71d51b78877491abc146d9ecf424891
Autor:
Amanda M. Clark, Chandi Magawa, Adriana Pliego-Zamora, Pauline Low, Max Reynolds, Stephen J. Ralph
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 140, Iss , Pp 111790- (2021)
The antitumor activity of the tea tree oil (TTO) derived product, Melaleuca Alternifolia Concentrate (MAC) was characterized mechanistically at the molecular and cellular level. MAC was analyzed for its anticancer activity against human prostate (LNC
Externí odkaz:
https://doaj.org/article/9ff7c89257574419a305f5122981b122
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Metastatic breast cancer remains a largely incurable and fatal disease with liver involvement bearing the worst prognosis. The danger is compounded by a subset of disseminated tumor cells that may lie dormant for years to decades before re-emerging a
Externí odkaz:
https://doaj.org/article/f388283e67f24b669df2281c62c26233
Publikováno v:
Molecular Cancer, Vol 16, Iss 1, Pp 1-14 (2017)
Abstract Background Our understanding of the multiple roles exosomes play during tumor progression is still very poor and the contribution of the normal tissue derived exosomes in distant seeding and tumor outgrowth has also not been widely appreciat
Externí odkaz:
https://doaj.org/article/2c59e80af8434b25b2795f9256726957
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7304 (2020)
Metastatic spread represents the leading cause of disease-related mortality among cancer patients. Many cancer patients suffer from metastatic relapse years or even decades after radical surgery for the primary tumor. This clinical phenomenon is expl
Externí odkaz:
https://doaj.org/article/169e4b187c4944fbbe185e6a9fd04085
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2566 (2019)
Tumor progression from an expanded cell population in a primary location to disseminated lethal growths subverts attempts at cures. It has become evident that these steps are driven in a large part by cancer cell-extrinsic signaling from the tumor mi
Externí odkaz:
https://doaj.org/article/eb83ca7dd5be4ec889d4eb09181882d0
Abstract P6-14-02: Hope for OTHERS – An organ donation program for metastatic breast cancer research
Autor:
Steffi Oesterreich, Lori Miller, Margaret Q. Rosenzweig, Tanner L. Bartholow, Megan Yates, Ashuvinee Elangovan, Laura Savariau, Allison N. Casey, Nolan Priedigkeit, Kai Ding, Abdalla Wedn, Jie Bin Liu, Daniel D. Brown, Tara Hyder, Geoffrey Pecar, Neil Carleton, Humberto Trejo Bittar, Daniel Geisler, Oscar Lopez-Nunez, Amanda M. Clark, Alan Wells, Partha Roy, Shannon Puhalla, Naomi Howard, Christine Needles, Susan Trent, Stephanie Walker, Christine Hodgdon, Rohit Bhargava, Jennifer M. Atkinson, Adrian V. Lee
Publikováno v:
Cancer Research. 83:P6-14
Background: Previous studies have shown that rapid autopsies (RA) provide a unique opportunity for tissue collection from patients who succumb to the disease. Because cancer patients are unable to donate their organs to other people, this program pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6261e0dd57fc3f8eac6ee1d3fae06538
https://doi.org/10.1158/1538-7445.sabcs22-p6-14-02
https://doi.org/10.1158/1538-7445.sabcs22-p6-14-02
Publikováno v:
Br J Cancer
BACKGROUND: Metastatic triple-negative breast cancer (mTNBC) is treated mainly with chemotherapy. However, resistance frequently occurs as tumours enter dormancy. Statins have been suggested as effective against cancer but as they prolong and promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a19a799c3e9a65d8bc161392b654a9
https://doi.org/10.1038/s41416-021-01529-0
https://doi.org/10.1038/s41416-021-01529-0
Publikováno v:
Semin Cancer Biol
The liver is the most commonly involved organ in metastases from a wide variety of solid tumors. The use of biologically and cellularly complex liver tissue systems have shown that tumor cell behavior and therapeutic responses are modulated within th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5f722e44a9e17dc4345c6a4ae47434
https://doi.org/10.1016/j.semcancer.2020.06.010
https://doi.org/10.1016/j.semcancer.2020.06.010