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Autor:
Katia R. M. Leite, Sabrina T. Reis, Yves Silva Teles Matos, J.M. Ferreira, Robson José de Almeida, Humberto Dellê, Amanda M Ramos Lima, Cleber Pinto Camacho, Miguel Srougi, José Pontes-Junior
Publikováno v:
International Urology and Nephrology. 52:1477-1482
Indoleamine 2,3-dioxygenase (IDO1) is an enzyme that acts as an immunomodulatory molecule. It is found in several types of cancer where it seems to be associated with tumor escape due to its immunosuppressive mechanisms. However, the role of IDO1 exp