Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Amanda M, Smith"'
Cardiotoxicity of venetoclax in patients with acute myeloid leukemia: comparison with anthracyclines
Autor:
Takeshi Onoue, Andrew H. Matthews, Azin Vakilpour, Yu Kang, Bénédicte Lefebvre, Amanda M. Smith, Shannon R. McCurdy, Michael G. Fradley, Joseph Carver, Jesse Chittams, Marielle Scherrer-Crosbie
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-5 (2024)
Abstract Venetoclax is a promising drug for patients with acute myeloid leukemia (AML) ineligible for anthracycline-based treatments. In rats, venetoclax is reported to cause myocardial injury. Our objectives were to report the frequency of cardiovas
Externí odkaz:
https://doaj.org/article/89a3cd17d3734fde80d7b51c6c464c87
Autor:
Amanda M. Smith
Publikováno v:
Tapuya, Vol 7, Iss 1 (2024)
ABSTRACTHow might the creation of digital research infrastructure for preserving archival materials in Latin America resemble the infrastructure of extractivism? This essay examines the development of a digital repository for one of the most importan
Externí odkaz:
https://doaj.org/article/7131c4aef1844ca581be4e577ad0d1b6
Autor:
Kasey J. Leger, Michael J. Absalon, Biniyam G. Demissei, Amanda M. Smith, Robert B. Gerbing, Todd A. Alonzo, Hari K. Narayan, Betsy A. Hirsch, Jessica A. Pollard, Bassem I. Razzouk, Kelly D. Getz, Richard Aplenc, E. Anders Kolb, Bonnie Ky, Todd M. Cooper
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionAnthracyclines are effective in treating acute myeloid leukemia (AML) but limited by cardiotoxicity. CPX-351, a liposomal daunorubicin and cytarabine, may provide therapeutic benefit with less cardiotoxicity. Acute changes in left ventric
Externí odkaz:
https://doaj.org/article/4f7d5c7ff98a44ee954f1d19f9442a1c
Autor:
Amanda M. Smith
An analysis of the political and ecological consequences of charting the Amazon River basin in narrative fiction, Mapping the Amazon examines how widely read novels from twentieth-century South America attempted to map the region for readers. Author
Autor:
Kasey J. Leger, Nora Robison, Hari K. Narayan, Amanda M. Smith, Tenaadam Tsega, Jade Chung, Amber Daniels, Zhen Chen, Virginia Englefield, Biniyam G. Demissei, Benedicte Lefebvre, Gemma Morrow, Ilona Dizon, Robert B. Gerbing, Reena Pabari, Kelly D. Getz, Richard Aplenc, Jessica A. Pollard, Eric J. Chow, W. H. Wilson Tang, William L. Border, Ritu Sachdeva, Todd A. Alonzo, E. Anders Kolb, Todd M. Cooper, Bonnie Ky
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundPediatric acute myeloid leukemia (AML) therapy is associated with substantial short- and long-term treatment-related cardiotoxicity mainly due to high-dose anthracycline exposure. Early left ventricular systolic dysfunction (LVSD) compromis
Externí odkaz:
https://doaj.org/article/b99055bf1d704eadae2a445572632039
Autor:
Kathleen M. Sturgeon, Amanda M. Smith, Elizabeth H. Federici, Namratha Kodali, Renée Kessler, Edward Wyluda, Leah V. Cream, Bonnie Ky, Kathryn H. Schmitz
Publikováno v:
BMC Sports Science, Medicine and Rehabilitation, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Purpose To evaluate the feasibility of a home-based moderate-to-vigorous intensity, phased (introduction, intermediate, maintenance), exercise prescription in breast cancer patients receiving cardiotoxic neoadjuvant chemotherapy. Methods Nin
Externí odkaz:
https://doaj.org/article/ab7e5c08172148f598f9d674ccac177b
Autor:
Amanda M. Smith, Taylor A. LaValle, Marwan Shinawi, Sai M. Ramakrishnan, Haley J. Abel, Cheryl A. Hill, Nicole M. Kirkland, Michael P. Rettig, Nichole M. Helton, Sharon E. Heath, Francesca Ferraro, David Y. Chen, Sangeeta Adak, Clay F. Semenkovich, Diana L. Christian, Jenna R. Martin, Harrison W. Gabel, Christopher A. Miller, Timothy J. Ley
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Germline mutations in the DNMT3A gene can cause an overgrowth syndrome associated with behavioural and hematopoietic phenotypes. Here the authors describe a mouse model of this syndrome that recapitulates many of these features, including conserved a
Externí odkaz:
https://doaj.org/article/5e0d8e3763324ed0920eb1d6b6fbeadf
Autor:
Amanda M. Smith, Jason W. Stull, Michelle D. Evason, J. Scott Weese, Thomas E. Wittum, Donald Szlosek, Andréia Gonçalves Arruda
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 3, Pp 1355-1360 (2021)
Abstract Background Leptospirosis is a zoonotic disease of concern and an investigation of recent spatio‐temporal trends of leptospirosis in dogs in the United States is needed. Leptospira PCR testing has become increasingly used in veterinary clin
Externí odkaz:
https://doaj.org/article/fa248875da9a475ea53bc0044f0b9301
Autor:
Amanda M. Smith, Angela M. Verdoni, Haley J. Abel, David Y. Chen, Shamika Ketkar, Elizabeth R. Leight, Christopher A. Miller, Timothy J. Ley
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104004- (2022)
Summary: Mutations in the gene encoding DNA methyltransferase 3A (DNMT3A) are the most common cause of clonal hematopoiesis and are among the most common initiating events of acute myeloid leukemia (AML). Studies in germline and somatic Dnmt3a knocko
Externí odkaz:
https://doaj.org/article/01b3d370f1c6454ba941449503cd5b03
Autor:
Jenica N. Upshaw, Rebecca A. Hubbard, Jian Hu, Justin C. Brown, Amanda M. Smith, Biniyam Demissei, Kathryn H. Schmitz, Bonnie Ky
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6122-6131 (2020)
Abstract Background Observational studies suggest that regular physical activity may reduce cardiovascular morbidity and cancer recurrence in survivors of breast cancer. The association between physical activity and cardiac function with breast cance
Externí odkaz:
https://doaj.org/article/a261e4167eaa4e6aa2519cd8f7e25b9e