Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Amanda M, Pattison"'
Autor:
Scott A. Waldman, Amanda M. Pattison, Jeffrey A. Rappaport, Joshua R Barton, Alicja Zalewski, Adam E. Snook, Ariana A Entezari
Publikováno v:
Cancer Biology & Therapy. 21:799-805
Most sporadic colorectal cancer reflects acquired mutations in the adenomatous polyposis coli (APC) tumor suppressor gene, while germline heterozygosity for mutant APC produces the autosomal dominant disorder Familial Adenomatous Polyposis (FAP) with
Autor:
Erik S. Blomain, Jeffrey A. Rappaport, Scott A. Waldman, Amanda M. Pattison, Adam E. Snook, Babar Bashir, Ellen M. Caparosa, Jonathan Stem
Publikováno v:
Cancer Biology & Therapy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Sporadic colorectal cancer initiates with mutations in APC or its degradation target β-catenin, producing TCF-dependent nuclear transcription driving tumorigenesis. The intestinal epithelial receptor, GUCY2C, with its canonical paracrine hormone gua
Autor:
Joshua R Barton, John C. Flickinger, Jeffrey A. Rappaport, Trevor R. Baybutt, Amanda M. Pattison, Adam E. Snook, Scott A. Waldman
Publikováno v:
Biomark Med
Gastrointestinal cancers encompass a diverse class of tumors arising in the GI tract, including esophagus, stomach, pancreas and colorectum. Collectively, gastrointestinal cancers compose a high fraction of all cancer deaths, highlighting an unmet ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8cb9a2c879e8667480f935b2f17f6b
https://europepmc.org/articles/PMC8293028/
https://europepmc.org/articles/PMC8293028/
Autor:
John C. Flickinger, Tingting Zhan, Trevor R. Baybutt, Jagmohan Singh, Adam E. Snook, Elinor Leong, Amanda M. Pattison, Robert D Carlson, Joshua R Barton, Ellen M. Caparosa, Babar Bashir, Scott A. Waldman, Jamin Roh, Jeffrey A. Rappaport
Publikováno v:
Journal for Immunotherapy of Cancer
BackgroundAdenovirus serotype 5 (Ad5) is a commonly used viral vector for transient delivery of transgenes, primarily for vaccination against pathogen and tumor antigens. However, endemic infections with Ad5 produce virus-specific neutralizing antibo
Autor:
Amanda M, Pattison, Joshua R, Barton, Ariana A, Entezari, Alicja, Zalewski, Jeff A, Rappaport, Adam E, Snook, Scott A, Waldman
Publikováno v:
Cancer Biology & Therapy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Most sporadic colorectal cancer reflects acquired mutations in the adenomatous polyposis coli (APC) tumor suppressor gene, while germline heterozygosity for mutant APC produces the autosomal dominant disorder Familial Adenomatous Polyposis (FAP) with
Autor:
John P. Lynch, Adam E. Snook, Amanda M. Pattison, Crystal L. Kraft, Jeffrey A. Rappaport, Scott A. Waldman
Publikováno v:
Oncotarget. 8:102923-102933
Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium. Their long life, lineage plasticity, and proliferative potential under
Autor:
Jeffrey A. Rappaport, Adam E. Snook, Allison A. Aka, Takami Sato, Scott A. Waldman, Amanda M. Pattison
Publikováno v:
Expert Review of Clinical Pharmacology. 10:549-557
Colorectal cancer remains the second leading cause of cancer death in the United States, and new strategies to prevent, detect, and treat the disease are needed. The receptor, guanylate cyclase C (GUCY2C), a tumor suppressor expressed by the intestin
Autor:
Fang Wang, Adam E. Snook, Scott A. Waldman, Mary Ann S. Crissey, Amanda M. Pattison, Crystal L. Kraft, John P. Lynch, Dante J. Merlino, Jeffrey A. Rappaport, Erik S. Blomain
Publikováno v:
Infection and Immunity. 84:3083-3091
Enterotoxigenic Escherichia coli (ETEC) causes ∼20% of the acute infectious diarrhea (AID) episodes worldwide, often by producing heat-stable enterotoxins (STs), which are peptides structurally homologous to paracrine hormones of the intestinal gua
Publikováno v:
World Journal of Gastroenterology
Colorectal cancer (CRC) is a major cause of cancer-related mortality and morbidity worldwide. While improved treatments have enhanced overall patient outcome, disease burden encompassing quality of life, cost of care, and patient survival has seen li
Publikováno v:
Cancer Biology & Therapy. 17:713-718
Despite advances in screening and prevention strategies, colorectal cancer (CRC) remains the second-leading cause of cancer-related death in the United States. Given this continued public health burden of CRC, there is a clear need for improved disea