Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner

Autor: Ross D. Hannan, Helena E. Richardson, Naomi C Mitchell, Timothy M. Johanson, Amanda Lee Jue Er, Nicola J Cranna, Leonie M. Quinn

Publikováno v: Development (Cambridge, England). 137(17)

An unresolved question regarding the RNA-recognition motif (RRM) protein Half pint (Hfp) has been whether its tumour suppressor behaviour occurs by a transcriptional mechanism or via effects on splicing. The data presented here demonstrate that Hfp a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e6a9a9894ab4fb5392be09925059ac
https://pubmed.ncbi.nlm.nih.gov/20667914

Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth.

Autor: Guo L; School of Biomedical Sciences, University of Melbourne, Parkville, VIC 3010, Australia., Zaysteva O; School of Biomedical Sciences, University of Melbourne, Parkville, VIC 3010, Australia., Nie Z; Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Mitchell NC; School of Biomedical Sciences, University of Melbourne, Parkville, VIC 3010, Australia., Amanda Lee JE; School of Biomedical Sciences, University of Melbourne, Parkville, VIC 3010, Australia., Ware T; Department of Surgery, University of Melbourne, Royal Melbourne Hospital, Parkville, VIC 3010, Australia., Parsons L; School of Biomedical Sciences, University of Melbourne, Parkville, VIC 3010, Australia., Luwor R; Department of Surgery, University of Melbourne, Royal Melbourne Hospital, Parkville, VIC 3010, Australia., Poortinga G; Peter MacCallum Cancer Centre, St. Andrews Place, East Melbourne, VIC 3002, Australia., Hannan RD; Department of Medicine, St. Vincent's Hospital, University of Melbourne, Parkville, VIC 3010, Australia Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra City, ACT 2600, Australia., Levens DL; Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Quinn LM; School of Biomedical Sciences, University of Melbourne, Parkville, VIC 3010, Australia l.quinn@unimelb.edu.au.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2016 Sep 19; Vol. 44 (16), pp. 7646-58. Date of Electronic Publication: 2016 May 20.