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pro vyhledávání: '"Amanda Lee Brink"'
Publikováno v:
Journal of the Advanced Practitioner in Oncology
Patients receiving ifosfamide as part of their cancer treatment are at risk for ifosfamide-related encephalopathy (IRE), a potentially serious adverse event affecting up to 60% of patients. Symptoms range from transient altered mental status to coma
Autor:
Jatin J. Shah, Funda Meric-Bernstam, Robert L. Coleman, David M. Gershenson, Fechukwu Akhmedzhanov, Shubham Pant, Heather Lin, Anil K. Sood, Shannon N. Westin, Bulent Yilmaz, Aung Naing, Cheuk Hong Leung, David S. Hong, Siqing Fu, Sarina Anne Piha-Paul, Amanda Lee Brink, Jing Gong, Lacey McQuinn, Amir A. Jazaeri, Apostolia Maria Tsimberidou
Publikováno v:
Journal of Clinical Oncology. 39:5565-5565
5565 Background: Selinexor is a first-in-class novel, oral potent selective inhibitor of nuclear export (SINE) which blocks Exportin-1 (XPO1) leading to nuclear accumulation and activation of tumor suppressor proteins and prevention of translation of