Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Amanda L. Wise"'
Autor:
Evelyn Rustia, Amanda L. Wise, Sharon DeChenne, Ariel R. Topletz-Erickson, JoAl Mayor, Anthony Lee, Luke Walker, Ben Dailey, Layth I. Abdulrasool, Christopher J. Endres, Stephen C. Alley
Publikováno v:
Journal of Clinical Pharmacology
Tucatinib is a potent tyrosine kinase inhibitor selective for human epidermal growth factor receptor 2 (HER2) approved by the US Food and Drug Administration for the treatment of HER2‐positive metastatic breast cancer and in development for other H
Autor:
Sid Ganguly, Soumen Paul, Joseph McGuirk, Jonathan D. Mahnken, Brea Lipe, Maegan L. Capitano, Dennis Allin, Hal E. Broxmeyer, Amanda L. Wise, Leyla Shune, Anurag K. Singh, Sunil Abhyankar, Abigale Berry, George A. Vielhauer, Mary J. Laughlin, Omar S. Aljitawi, Christopher Lominska, Tara L. Lin, Avishek Ganguly, Amy Cantilena
Publikováno v:
Blood. 128:3000-3010
Umbilical cord blood (UCB) engraftment is in part limited by graft cell dose, generally one log less than that of bone marrow (BM)/peripheral blood (PB) cell grafts. Strategies toward increasing hematopoietic stem/progenitor cell (HSPC) homing to BM
Autor:
Kevin F. Ginn, Kyle Kimura, Robyn Gartrell, Daniel Ziazadeh, Ben Fangman, Faris Farassati, Kaoru Terai, Emma Borrego-Diaz, Amanda L. Wise, Kushal J. Shah, Brandon Ricke, Sharad C. Mathur
Publikováno v:
Journal of Neuro-Oncology. 130:99-110
Medulloblastoma (MDB) represents a major form of malignant brain tumors in the pediatric population. A vast spectrum of research on MDB has advanced our understanding of the underlying mechanism, however, a significant need still exists to develop no
Autor:
Faris Farassati, Atabak Asvadi Kermani, Elham Patrad, Mohammad Taha, Kun Wang, Bashar Abdulkarim, Kristina Lialyte, Mina Soleimani, Tuba Esfandyari, Emma Borrego-Diaz, Amanda L. Wise, Mohamad Ezzeldin, Stephen K. Williamson, Alex Rouyanian, Mojtaba Olyaee, Warner Peng
Publikováno v:
Molecular Oncology. 8:1043-1053
Ral (Ras like) leads an important proto‐oncogenic signaling pathway down‐stream of Ras. In this work, RalA was found to be significantly overactivated in hepatocellular carcinoma (HCC) cells and tissues as compared to non‐malignant samples. Oth
Autor:
Devon Koestler, Tara L. Lin, Amanda L. Wise, Stefan Graw, Omar S. Aljitawi, Andrew K. Godwin, Brea Lipe
Publikováno v:
Blood. 128:4411-4411
Introduction: Multiple Myeloma (MM) is an incurable cancer characterized by a pre-malignant clonal phase of disease called monoclonal gammopathy of undetermined significance (MGUS). Most patients with MGUS do not develop overt MM and the biology unde
Autor:
Sunil Abhyankar, Dennis Allin, Joseph McGuirk, Leyla Shune, Omar S. Aljitawi, Siddhartha Ganguly, Alain Mina, Amy Cantilena, Anurag K. Singh, Tara L. Lin, Amanda L. Wise
Publikováno v:
Journal of Clinical Oncology. 34:7048-7048
7048Background: Umbilical cord blood (UCB) transplantation has a major drawback related to delayed or failed engraftment which increases post-transplant mortality. In a pilot clinical trial, we hav...
Autor:
Omar S. Aljitawi, Joseph D. Fontes, Tara L. Lin, Amanda L. Wise, Hemantkumar Chavan, Partha Kasturi, Abigale Berry, Brea Lipe
Publikováno v:
Journal of Clinical Oncology. 34:e18518-e18518
e18518Background: Insights into the biology of chemotherapy resistance may suggest novel strategies to treat Acute Myeloid Leukemia (AML). We examined the role of hyperbaric oxygen (HBO) in AML sen...
Autor:
Partha Kasturi, Omar S. Aljitawi, Abigale Berry, Brea Lipe, Tara L. Lin, Amanda L. Wise, Joseph D. Fontes
Publikováno v:
Blood. 126:1399-1399
Introduction: Chemotherapy resistance remains a significant challenge in the treatment of adults with Acute Myeloid Leukemia (AML). Although new targets and novel agents are under clinical investigation, the majority of AML patients are treated with
Autor:
Maegan L. Capitano, Aaron Cheung, Amanda L. Wise, Hal E. Broxmeyer, Dandan Li, George A. Vielhauer, Tara L. Lin, Omar S. Aljitawi, Brea Lipe, Soumen Paul, Mary J. Laughlin
Publikováno v:
Blood. 126:1870-1870
Background: Previously, we demonstrated that host pre-treatment with hyperbaric oxygen (HBO) improves engraftment of umbilical cord blood (UCB) CD34+ cells in a transplant murine model. Recent data suggest that erythropoietin (EPO) determines the fat
Autor:
Tuba Esfandyari, Victor F. Mautner, Kaoru Terai, Luis F. Parada, Emma Borrego-Diaz, Amanda L. Wise, Sarah A. Taylor, Fariba Behbod, Faris Farassati, Melanie Spyra, Kristina Lialyte, Meena Upadhyaya
Publikováno v:
Journal of neuro-oncology. 108(3)
Cancer stem cells (CSCs) are believed to be the regenerative pool of cells responsible for repopulating tumors. Gaining knowledge about the signaling characteristics of CSCs is important for understanding the biology of tumors and developing novel an