Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Amanda L. Wacker"'
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Akademický článek
Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts
Autor: Maicon Landim-Vieira, Matthew C Childers, Amanda L Wacker, Michelle Rodriquez Garcia, Huan He, Rakesh Singh, Elizabeth A Brundage, Jamie R Johnston, Bryan A Whitson, P Bryant Chase, Paul ML Janssen, Michael Regnier, Brandon J Biesiadecki, J Renato Pinto, Michelle S Parvatiyar
Publikováno v: eLife, Vol 11 (2022)
Phosphorylation and acetylation of sarcomeric proteins are important for fine-tuning myocardial contractility. Here, we used bottom-up proteomics and label-free quantification to identify novel post-translational modifications (PTMs) on β-myosin hea
Externí odkaz: https://doaj.org/article/38e39ac9728c48009835c5d2747080b4
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2
Long-read sequencing reveals increased occurrence of genomic variants and adenosine methylation in Bacillus pumilus SAFR-032 after long-duration flight exposure onboard the International Space Station
Autor: S. Marshall Ledford, Bianca M. Serda, Samantha M. Waters, Jordan M. McKaig, Amanda L. Wacker, Joseph Varelas, Patrick M. Nicoll, Sonali Verma, David J. Smith, Kasthuri Venkateswaran
Publikováno v: International Journal of Astrobiology. 20:435-444
Bacillus pumilus SAFR-032, an endospore-forming bacterial strain, was investigated to determine its methylation pattern (methylome) change, compared to ground control, after direct exposure to space conditions onboard the International Space Station
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::806212ce0d02634c8001ba92d8338e8c
https://doi.org/10.1017/s1473550421000343
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3
Essential roles of the dystrophin-glycoprotein complex in different cardiac pathologies
Autor: Isela C. Valera, Andrew P. Landstrom, Amanda L. Wacker, Michelle S. Parvatiyar, Hyun Seok Hwang, Christina Holmes, Orlando Laitano
Publikováno v: Advances in Medical Sciences. 66:52-71
The dystrophin-glycoprotein complex (DGC), situated at the sarcolemma dynamically remodels during cardiac disease. This review examines DGC remodeling as a common denominator in diseases affecting heart function and health. Dystrophin and the DGC ser
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57dc0233d08ad7cf89dd5777b9073ffc
https://doi.org/10.1016/j.advms.2020.12.004
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6
Systems analysis of benign bladder disorders: insights from omics analysis
Autor: Ali Hashemi Gheinani, Rosalyn M. Adam, Amanda L. Wacker, Alexander Bigger-Allen
Publikováno v: American Journal of Physiology-Renal Physiology. 318:F901-F910
The signaling pathways and effectors that drive the response of the bladder to nonmalignant insults or injury are incompletely defined. Interrogation of biological systems has been revolutionized by the ability to generate high-content data sets that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d028320c475c61e9bba644bed78f769a
https://doi.org/10.1152/ajprenal.00496.2019
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7
Abstract P421: Analysis Of The Functional Relevance Of Human Beta-myosin Heavy Chain Post-translational Modifications
Autor: Michelle S. Parvatiyar, P.B. Chase, Maicon Landim-Vieira, J. Renato Pinto, Matthew C. Childers, Bryan A. Whitson, Brandon J. Biesiadecki, Rakesh K. Singh, Elizabeth A. Brundage, Amanda L. Wacker, Paul M.L. Janssen, Michelle C. Rodriguez Garcia, Michael Regnier
Publikováno v: Circulation Research. 129
Sarcomeric proteins have been shown to be a target of post-translational modifications (PTMs). Phosphorylation and acetylation of several sarcomeric proteins have been reported to be important for fine-tuning of myocardial contractility. Given the em
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b34f509fa4704926494b61bd0e80c287
https://doi.org/10.1161/res.129.suppl_1.p421
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9
A Single Cell Dissociation Approach for Molecular Analysis of Urinary Bladder in the Mouse Following Spinal Cord Injury
Autor: Yao Gao, Amanda L. Wacker, Rosalyn M. Adam, Diane R. Bielenberg, Yaser Heshmati, Ali Hashemi Gheinani, George Lambrinos, Hussein Atta, Alex Bigger-Allen
Publikováno v: Journal of visualized experiments : JoVE. (160)
We describe the implementation of spinal cord injury in mice to elicit detrusor-sphincter dyssynergia, a functional bladder outlet obstruction, and subsequent bladder wall remodeling. To facilitate assessment of the cellular composition of the bladde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19079bdac98fcd26f6cfc67ebebd32e1
https://pubmed.ncbi.nlm.nih.gov/32628176
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