Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Amanda L. Rinkenbaugh"'
Autor:
Reid T. Powell, Amanda L. Rinkenbaugh, Lei Guo, Shirong Cai, Jiansu Shao, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Chunxiao Fu, Yuan Qi, Faiza Baameur Hancock, Jason B. White, Clifford Stephan, Peter J. Davies, Stacy Moulder, W. Fraser Symmans, Jeffrey T. Chang, Helen Piwnica-Worms
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Triple negative breast cancer (TNBC) accounts for 15–20% of breast cancer cases in the United States. Systemic neoadjuvant chemotherapy (NACT), with or without immunotherapy, is the current standard of care for patients with early-stage TN
Externí odkaz:
https://doaj.org/article/388c05310d9142b793c6b22617755d55
Autor:
Gloria V. Echeverria, Shirong Cai, Yizheng Tu, Jiansu Shao, Emily Powell, Abena B. Redwood, Yan Jiang, Aaron McCoy, Amanda L. Rinkenbaugh, Rosanna Lau, Alexander J. Trevarton, Chunxiao Fu, Rebekah Gould, Elizabeth E. Ravenberg, Lei Huo, Rosalind Candelaria, Lumarie Santiago, Beatriz E. Adrada, Deanna L. Lane, Gaiane M. Rauch, Wei T. Yang, Jason B. White, Jeffrey T. Chang, Stacy L. Moulder, W. Fraser Symmans, Susan G. Hilsenbeck, Helen Piwnica-Worms
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Patient-derived xenograft (PDX) models of breast cancer are an effective discovery platform and tool for preclinical pharmacologic testing and biomarker identification. We established orthotopic PDX models of triple negative breast cancer (T
Externí odkaz:
https://doaj.org/article/1aeaec90b47b427c8b0d10b0dad9ddf6
Autor:
Vidya C. Sinha, Amanda L. Rinkenbaugh, Mingchu Xu, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Jiansu Shao, Yuan Qi, John A. Zebala, Dean Y. Maeda, Florencia McAllister, Helen Piwnica-Worms
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The classification of breast lesions as indolent or aggressive to tailor treatment is crucial. Here, the authors use single-cell transcriptomics and multiparametric imaging of a breast cancer mouse model, report distinct tumor-immune features for the
Externí odkaz:
https://doaj.org/article/edf450673bba4946ad0410cdc2344397
Publikováno v:
Cells, Vol 5, Iss 2, p 16 (2016)
The NF-κB transcription factor pathway is a crucial regulator of inflammation and immune responses. Additionally, aberrant NF-κB signaling has been identified in many types of cancer. Downstream of key oncogenic pathways, such as RAS, BCR-ABL, and
Externí odkaz:
https://doaj.org/article/87495ce84b1d416e9004f01fc712f906
Publikováno v:
Cancer Research. 79:P3-07
This abstract was withdrawn by the authors. Citation Format: Rinkenbaugh AL, Sinha VC, Zhang X, Shao J, Piwnica-Worms H. Withdrawn [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 Dec 4-8; San Antonio, TX. Philadelphi
Autor:
Amanda L. Rinkenbaugh, Vidya C. Sinha, Pankaj Singh, Yuan Qi, Jiansu Shao, Xiaomei Zhang, Gloria V. Echeverria, W. Fraser Symmans, Stacy L. Moulder, Helen Piwnica-Worms
Publikováno v:
Cancer Research. 82:1595-1595
Shifts in tumor cell phenotype in response to selective pressures (i.e. changing microenvironments, drug treatments) pose one of the biggest obstacles to successful breast cancer therapies. Phenotypically diverse breast tumor and stroma subpopulation
Autor:
Mingchu Xu, Florencia McAllister, John A. Zebala, Jiansu Shao, Sabrina Jeter-Jones, Helen Piwnica-Worms, Xinhui Zhou, Amanda L. Rinkenbaugh, Dean Y. Maeda, Yuan Qi, Vidya C. Sinha, Xiaomei Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
There is an unmet clinical need for stratification of breast lesions as indolent or aggressive to tailor treatment. Here, single-cell transcriptomics and multiparametric imaging applied to a mouse model of breast cancer reveals that the aggressive tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b4f5dfab286ef1adf1a7aad963bb77
https://doi.org/10.21203/rs.3.rs-179498/v1
https://doi.org/10.21203/rs.3.rs-179498/v1
Autor:
Amanda L. Rinkenbaugh, Jiansu Shao, Xiaomei Zhang, Gloria V. Echeverria, Helen Piwnica-Worms, Stacy L. Moulder, W. Fraser Symmans, Vidya C. Sinha
Publikováno v:
Cancer Research. 80:PR01-PR01
Shifts in tumor phenotype in response to selective pressures (i.e. changing microenvironments, drug treatments) pose one of the biggest obstacles to successful cancer therapies. Phenotypically diverse tumor and stroma subpopulations, and interactions
Autor:
Albert S. Baldwin, Denise E. Dunn, William A. Weiss, Anders Persson, Barbara Calamini, Patricia C. Cogswell, Donald C. Lo, Amanda L. Rinkenbaugh
Publikováno v:
Oncotarget
Oncotarget, vol 7, iss 43
Oncotarget, vol 7, iss 43
// Amanda L. Rinkenbaugh 1,2 , Patricia C. Cogswell 2,3 , Barbara Calamini 4 , Denise E. Dunn 4 , Anders I. Persson 5,6 , William A. Weiss 5,6 , Donald C. Lo 4 and Albert S. Baldwin 2 1 Department of Pathology and Laboratory Medicine, University of N
Autor:
Vidya C. Sinha, Xiaomei Zhang, Helen Piwnica-Worms, Amanda L. Rinkenbaugh, Xinhui Zhou, Mingchu Xu
Publikováno v:
Cancer Research. 80:2822-2822
Introduction: Ductal carcinoma in situ is a non-invasive lesion of the breast that comprises ~20% of newly diagnosed breast cancers in the United States. Prospectively distinguishing indolent from aggressive lesions has been a major clinical challeng