Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Amanda L. Loshbaugh"'
Autor:
Julia Koehler Leman, Sergey Lyskov, Steven M. Lewis, Jared Adolf-Bryfogle, Rebecca F. Alford, Kyle Barlow, Ziv Ben-Aharon, Daniel Farrell, Jason Fell, William A. Hansen, Ameya Harmalkar, Jeliazko Jeliazkov, Georg Kuenze, Justyna D. Krys, Ajasja Ljubetič, Amanda L. Loshbaugh, Jack Maguire, Rocco Moretti, Vikram Khipple Mulligan, Morgan L. Nance, Phuong T. Nguyen, Shane Ó Conchúir, Shourya S. Roy Burman, Rituparna Samanta, Shannon T. Smith, Frank Teets, Johanna K. S. Tiemann, Andrew Watkins, Hope Woods, Brahm J. Yachnin, Christopher D. Bahl, Chris Bailey-Kellogg, David Baker, Rhiju Das, Frank DiMaio, Sagar D. Khare, Tanja Kortemme, Jason W. Labonte, Kresten Lindorff-Larsen, Jens Meiler, William Schief, Ora Schueler-Furman, Justin B. Siegel, Amelie Stein, Vladimir Yarov-Yarovoy, Brian Kuhlman, Andrew Leaver-Fay, Dominik Gront, Jeffrey J. Gray, Richard Bonneau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Computational methods are becoming an increasingly important part of biological research. Using the Rosetta framework as an example, the authors demonstrate how community-driven development of computational methods can be done in a reproducible and r
Externí odkaz:
https://doaj.org/article/7ccba8c202cd473d906c246ef7b2eb77
Autor:
Dominik Gront, Kresten Lindorff-Larsen, Jack Maguire, Jens Meiler, Christopher D. Bahl, Jason S. Fell, Chris Bailey-Kellogg, Andrew M. Watkins, Frank DiMaio, Daniel P. Farrell, Jared Adolf-Bryfogle, Julia Koehler Leman, Frank D. Teets, Vladimir Yarov-Yarovoy, Ajasja Ljubetič, Shannon T. Smith, William A. Hansen, Steven M. Lewis, Justyna Krys, Shourya S. Roy Burman, Amelie Stein, Rhiju Das, David Baker, Vikram Khipple Mulligan, Jason W. Labonte, Georg Kuenze, William R. Schief, Rebecca F. Alford, Shane Ó Conchúir, Hope Woods, Tanja Kortemme, Johanna K. S. Tiemann, Sagar D. Khare, Sergey Lyskov, Ziv Ben-Aharon, Ora Schueler-Furman, Amanda L. Loshbaugh, Richard Bonneau, Brahm J. Yachnin, Andrew Leaver-Fay, Kyle A. Barlow, Phuong T. Nguyen, Jeliazko R. Jeliazkov, Jeffrey J. Gray, Justin B. Siegel, Rocco Moretti, Ameya Harmalkar, Brian Kuhlman
Each year vast international resources are wasted on irreproducible research. The scientific community has been slow to adopt standard software engineering practices, despite the increases in high-dimensional data, complexities of workflows, and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae3b538a88ca76a15e111345bd76765
https://doi.org/10.1101/2021.04.04.438423
https://doi.org/10.1101/2021.04.04.438423
Autor:
Michael C. Thompson, Tanja Kortemme, Daniel J. Mandell, Kyle A. Barlow, Jenna Pellegrino, Yao-Ming Huang, James S. Fraser, Amanda L. Loshbaugh, Anum A. Glasgow, Noah Ollikainen, Mark J. S. Kelly, Ryan Ritterson, Cody Krivacic, Deborah Jeon, Roland A. Pache
Publikováno v:
Science
Science (New York, N.Y.), vol 366, iss 6468
Science (New York, N.Y.), vol 366, iss 6468
Sense and respond Many signaling pathways start with cellular proteins sensing and responding to small molecules. Despite advances in protein design, creating a protein-based sense-and-respond system remains challenging. Glasgow et al. designed bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3b5ab92ce33debbe89d63e90254e35
https://europepmc.org/articles/PMC7343396/
https://europepmc.org/articles/PMC7343396/
Comparison of Rosetta flexible-backbone computational protein design methods on binding interactions
Autor:
Tanja Kortemme, Amanda L. Loshbaugh
Publikováno v:
Proteins
Computational design of binding sites in proteins remains difficult, in part due to limitations in our current ability to sample backbone conformations that enable precise and accurate geometric positioning of side chains during sequence design. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b11461db52f83fd8e4b23b55ebf017
https://europepmc.org/articles/PMC6901717/
https://europepmc.org/articles/PMC6901717/
Autor:
Klaus M. Hahn, Mayumi Nakamura, Amanda L. Loshbaugh, Fukutoshi Shirai, Brian Kuhlman, Yi I. Wu, Akiko Hayashi-Takagi, Haruo Kasai, Sho Yagishita
Publikováno v:
Nature
Summary Dendritic spines are the major loci of synaptic plasticity and are considered as possible structural correlates of memory. Nonetheless, systematic manipulation of specific subsets of spines in the cortex has been unattainable, and thus, the l