Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amanda L Vegoe"'
Autor:
Lina E Tze, Brian R Schram, Kong-Peng Lam, Kristin A Hogquist, Keli L Hippen, Jiabin Liu, Susan A Shinton, Kevin L Otipoby, Peter R Rodine, Amanda L Vegoe, Manfred Kraus, Richard R Hardy, Mark S Schlissel, Klaus Rajewsky, Timothy W Behrens
Publikováno v:
PLoS Biology, Vol 3, Iss 3, p e82 (2005)
In developing B lymphocytes, a successful V(D)J heavy chain (HC) immunoglobulin (Ig) rearrangement establishes HC allelic exclusion and signals pro-B cells to advance in development to the pre-B stage. A subsequent functional light chain (LC) rearran
Externí odkaz:
https://doaj.org/article/fb872538aa824b9d9c88f9a8f5d24eae
Autor:
Peter A. Larsen, Ferenc Tóth, Yi Wen Chai, Juan E. Abrahante, Manci Li, Timothy O'Brien, Amanda L. Vegoe, Beth A. Lindborg
Despite holding great therapeutic potential, existing protocols for in vitro chondrogenesis and hyaline cartilage production from human induced pluripotent stem cells (hiPSC) are laborious and complex with unclear long-term consequences. Here, we dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8288998478bc43a907f291979c01577
https://doi.org/10.1101/2021.09.21.461213
https://doi.org/10.1101/2021.09.21.461213
Autor:
Timothy O'Brien, Weili Chen, Kerri T. Haider, Qi Wang, Efrosini Kokkoli, Amanda L. Vegoe, James R. Dutton, Beth A. Lindborg, Paul J. Orchard, Francisco Pelaez, John H. Brekke, Cindy R. Eide, Jakub Tolar, Scott L. Venhuizen, Connor B. Ulrich, Sandhya Subramaniam, Carolyn M. Scott, Susan A. Keirstead
Publikováno v:
Stem Cells Translational Medicine. 5:970-979
Tissue organoids are a promising technology that may accelerate development of the societal and NIH mandate for precision medicine. Here we describe a robust and simple method for generating cerebral organoids (cOrgs) from human pluripotent stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfeda95660d8b5dea9d18c59f770f386
https://doi.org/10.5966/sctm.2015-0305
https://doi.org/10.5966/sctm.2015-0305
Autor:
Richard R. Hardy, Lydia Najera, Jiabin Liu, Amanda L. Vegoe, Keli L. Hippen, Michael A. Farrar, Brian R. Schram, Timothy W. Behrens, Lina E. Tze, Laura B. Ramsey
Publikováno v:
Experts@Minnesota
BCR editing in the bone marrow contributes to B cell tolerance by orchestrating secondary Ig rearrangements in self-reactive B cells. We have recently shown that loss of the BCR or a pharmacologic blockade of BCR proximal signaling pathways results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e027d8f6ed7239e3903171fe7a94b2
https://doi.org/10.4049/jimmunol.180.7.4728
https://doi.org/10.4049/jimmunol.180.7.4728
Autor:
Matthew A. Burchill, Marc K. Jenkins, H. Hamlet Chu, Kieng B. Vang, Jianying Yang, Chan-Wang J. Lio, Chyi-Song Hsieh, Amanda L. Vegoe, Michael A. Farrar, James J. Moon
Publikováno v:
Immunity. 28(1):112-121
SummaryAppropriate development of regulatory T (Treg) cells is necessary to prevent autoimmunity. Neonatal mice, unlike adults, lack factors required for Treg cell development. It is unclear what these missing factors are. However, signals emanating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0888dad4ef7d68400cca257ae48aad77
Light chain receptor editing is an important mechanism that prevents B cell self-reactivity. We have previously shown that tonic signaling through the BCR represses RAG expression at the immature B cell stage, and that initiation of light chain rearr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601754b6289cfb5a4df194850e320470
https://europepmc.org/articles/PMC3026880/
https://europepmc.org/articles/PMC3026880/
Autor:
Timothy W. Behrens, Keli L. Hippen, Jiabin Liu, P. Ruiz, George Karypis, Amanda L. Vegoe, Gary S. Gilkeson
Publikováno v:
Genes and immunity. 7(2)
MRLlpr mice develop spontaneous systemic autoimmunity with many hallmarks of the human disease systemic lupus erythematosus. Although a variety of genes have been implicated in this model, disease pathogenesis is still poorly understood. In an effort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513b113dc84ec099449002c15c196380
https://pubmed.ncbi.nlm.nih.gov/16508641
https://pubmed.ncbi.nlm.nih.gov/16508641
Autor:
Timothy W. Behrens, Richard R. Hardy, Susan A. Shinton, Kong-Peng Lam, Mark S. Schlissel, Amanda L. Vegoe, Jiabin Liu, Klaus Rajewsky, Keli L. Hippen, Kristin A. Hogquist, Peter R. Rodine, Brian R. Schram, Kevin L. Otipoby, Manfred Kraus, Lina E. Tze
Publikováno v:
PLoS Biology
PLoS Biology, Vol 3, Iss 3, p e82 (2005)
PLoS Biology, Vol 3, Iss 3, p e82 (2005)
In developing B lymphocytes, a successful V(D)J heavy chain (HC) immunoglobulin (Ig) rearrangement establishes HC allelic exclusion and signals pro-B cells to advance in development to the pre-B stage. A subsequent functional light chain (LC) rearran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7b2cc8cd834475d8eb973a1a9b0948
https://pubmed.ncbi.nlm.nih.gov/15752064
https://pubmed.ncbi.nlm.nih.gov/15752064
Autor:
Matthew A. Burchill, Amanda L. Vegoe, Michael A. Farrar, Shawn A. Mahmud, Jianying Yang, Kieng B. Vang
Publikováno v:
Experts@Minnesota
Common gamma chain (gammac)-receptor dependent cytokines are required for regulatory T cell (Treg) development as gammac(-/-) mice lack Tregs. However, it is unclear which gammac-dependent cytokines are involved in this process. Furthermore, thymic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea13cbd9b37694e709c867c178fbf271
https://experts.umn.edu/portal/en/publications/il2-7-and-15-but-not-thymic-stromal-lymphopoeitin-redundantly-govern-cd4foxp3-regulatory-t-cell-development(f3746fdf-49ec-4631-ae66-8e8dd7b54b7b).html
https://experts.umn.edu/portal/en/publications/il2-7-and-15-but-not-thymic-stromal-lymphopoeitin-redundantly-govern-cd4foxp3-regulatory-t-cell-development(f3746fdf-49ec-4631-ae66-8e8dd7b54b7b).html