Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amanda L Cleaver"'
Autor:
Robbert G van der Most, Andrew J Currie, Amanda L Cleaver, Joanne Salmons, Anna K Nowak, Sathish Mahendran, Irma Larma, Amy Prosser, Bruce W S Robinson, Mark J Smyth, Anthony A Scalzo, Mariapia A Degli-Esposti, Richard A Lake
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6982 (2009)
BACKGROUND:Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized t
Externí odkaz:
https://doaj.org/article/13dc5af7b53147ddaccffeb6b7996fb7
Autor:
Wayne J. Aston, W. Joost Lesterhuis, Louis Boon, Ian M. Dick, Jenette Creaney, Robert A. Holt, Bruce W. S. Robinson, Andrea Khong, Jonathan Chee, Scott A. Fisher, Shaokang Ma, Richard A. Lake, Amanda L. Cleaver, Jessica N Solin
Publikováno v:
Immunity, Inflammation and Disease. 5:16-28
Introduction Regulatory T cells (Treg) play an important role in suppressing anti- immunity and their depletion has been linked to improved outcomes. To better understand the role of Treg in limiting the efficacy of anti-cancer immunity, we used a Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e4fda05a74492c222f7990253a7c8f8
https://doi.org/10.1002/iid3.136
https://doi.org/10.1002/iid3.136
Autor:
Shaohua H. Ren, Amanda Segal, Julius F. Varano della Vergiliana, Ming Yan Xu, Y. C. Gary Lee, Sally M. Lansley, Amanda L. Cleaver
Publikováno v:
Respirology. 19:1025-1033
Background and objective Mesothelioma is an incurable cancer with a rising global incidence. Intrapleural delivery of a commercially available compound made up of proteins produced by Staphylococcus aureus has been used clinically to induce pleurodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ebe43274493a843a175730680f98686
https://doi.org/10.1111/resp.12351
https://doi.org/10.1111/resp.12351
Autor:
Scott A, Fisher, Wayne J, Aston, Jonathan, Chee, Andrea, Khong, Amanda L, Cleaver, Jessica N, Solin, Shaokang, Ma, W Joost, Lesterhuis, Ian, Dick, Robert A, Holt, Jenette, Creaney, Louis, Boon, Bruce, Robinson, Richard A, Lake
Publikováno v:
Immunity, Inflammation and Disease
Introduction Regulatory T cells (Treg) play an important role in suppressing anti‐ immunity and their depletion has been linked to improved outcomes. To better understand the role of Treg in limiting the efficacy of anti‐cancer immunity, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d64078f9062b2a31d86581da29d3cde3
https://pubmed.ncbi.nlm.nih.gov/28250921
https://pubmed.ncbi.nlm.nih.gov/28250921
Autor:
Ben Wylie, Alison M. McDonnell, Amanda L. Cleaver, Andrew J. Currie, Richard A. Lake, Matthew Brown, Bruce W. S. Robinson, Kasia Kania
Publikováno v:
Oncoimmunology
It is widely accepted that generation of tumor specific CD8+ T-cell responses occur via cross-priming; however the source of tumor antigen for this event is unknown. We examined the source and form of tumor antigen required for cross-presentation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ea1dcccca0de3acc514b9a97acdefd
http://europepmc.org/articles/PMC3489739
http://europepmc.org/articles/PMC3489739
Autor:
Amanda L. Cleaver, Amy Prosser, Robbert van der Most, Bruce W. S. Robinson, Andrew J. Currie, Gordon J. Freeman, Alison M. McDonnell
Publikováno v:
The Journal of Immunology. 183:7898-7908
Tumors have evolved multiple mechanisms to evade immune destruction. One of these is expression of T cell inhibitory ligands such as programmed death-ligand 1 (PD-L1; B7-H1). In this study, we show that PD-L1 is highly expressed on mesothelioma tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333c1a3bfaf8895a5b1bd6d0ed4f30b4
https://doi.org/10.4049/jimmunol.0901060
https://doi.org/10.4049/jimmunol.0901060
Autor:
Amanda L. Cleaver, Muhammad Fahmi Alatas, Bruce W. S. Robinson, Theresa Connor, Andrew J. Currie, Richard A. Lake, Andrea Khong, S. Broomfield, Willem Joost Lesterhuis, Scott A. Fisher, Ben Wylie
Publikováno v:
BMC Cancer
Background Tumor debulking surgery followed by adjuvant chemotherapy or radiotherapy is a standard treatment for many solid malignancies. Although this approach can be effective, it often has limited success against recurrent or metastatic cancers an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e4f699c0050116a95eff8d26aea0c0
https://doi.org/10.1186/1471-2407-14-969
https://doi.org/10.1186/1471-2407-14-969
Autor:
Bruce W. S. Robinson, W. Joost Lesterhuis, Amanda L. Cleaver, Richard A. Lake, Devina D. Lakhiani, Theresa Connor, Scott A. Fisher, Andrea Khong, Ben Wylie
Publikováno v:
Journal of Translational Medicine
Background: This study was conducted to determine if anti-tumor vaccination administered prior to partial debulking surgery could improve survival using a murine solid tumour model. Methods: Tumor incidence and survival rates were compared in mice be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cec7d3c000f6ef93bba3682887df53
https://doi.org/10.1186/s12967-014-0245-7
https://doi.org/10.1186/s12967-014-0245-7
Autor:
Sally M, Lansley, Julius F, Varano Della Vergiliana, Amanda L, Cleaver, Shaohua H, Ren, Amanda, Segal, Ming Yan, Xu, Y C Gary, Lee
Publikováno v:
Respirology (Carlton, Vic.). 19(7)
Mesothelioma is an incurable cancer with a rising global incidence. Intrapleural delivery of a commercially available compound made up of proteins produced by Staphylococcus aureus has been used clinically to induce pleurodesis. We investigate if thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::013057c49cbddc5813ce25ace3ddf9c6
https://pubmed.ncbi.nlm.nih.gov/25139703
https://pubmed.ncbi.nlm.nih.gov/25139703
Autor:
Stephen P. Hunger, Ursula R. Kees, Alex H. Beesley, David L. Baker, Martin J. Firth, Nina C. Sturges, Rebecca A O'Leary, Amanda L. Cleaver
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 9, Iss 1, p 105 (2010)
Molecular Cancer, Vol 9, Iss 1, p 105 (2010)
Background Continuous complete clinical remission in T-cell acute lymphoblastic leukemia (T-ALL) is now approaching 80% due to the implementation of aggressive chemotherapy protocols but patients that relapse continue to have a poor prognosis. Such p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c154d5a31bccdf640b4829571dcfba
https://doi.org/10.1186/1476-4598-9-105
https://doi.org/10.1186/1476-4598-9-105