Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Amanda L, Roth"'
Autor:
Gladys C. Chemwor, Ben M. Andagalu, Irene A. Onyango, Benjamin H. Opot, Raphael O. Okoth, Redemptah A. Yedah, Jackline A. Juma, Edwin W. Mwakio, Dancan M. Wakoli, Joseph G. Amwoma, Agnes C. Cheruiyot, Dennis W. Juma, Bernhards R. Ogutu, Timothy E. Egbo, Eric C. Garges, Amanda L. Roth, Edwin Kamau, Oliver J. Watson, Hoseah M. Akala
Publikováno v:
International Journal of Infectious Diseases, Vol 132, Iss , Pp 17-25 (2023)
Objectives: This study examined the treatment response of mixed vs single-species Plasmodium falciparum infections to artemisinin-based combination therapies (ACTs). Methods: A total of 1211 blood samples collected on days 0, 7, 14, 21, 28, 35, and 4
Externí odkaz:
https://doaj.org/article/d19083ff7cf44a0d9b137282179c1b84
Autor:
Jackson M. Muema, James M. Mutunga, Meshack A. Obonyo, Merid N. Getahun, Ramadhan S. Mwakubambanya, Hoseah M. Akala, Agnes C. Cheruiyot, Redemptah A. Yeda, Dennis W. Juma, Ben Andagalu, Jaree L. Johnson, Amanda L. Roth, Joel L. Bargul
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background The unmet demand for effective malaria transmission-blocking agents targeting the transmissible stages of Plasmodium necessitates intensive discovery efforts. In this study, a bioactive bisbenzylisoquinoline (BBIQ), isoliensinine,
Externí odkaz:
https://doaj.org/article/be6482cc39094cfb87687c85f9ebef5d
Autor:
Dennis W. Juma, Benjamin H. Opot, Hosea M. Akala, Amanda L. Roth, Ben M. Andagalu, Jennifer M. Mutisya, Johnson K. Kinyua, Victor A. Mobegi, Raphael O. Okoth, Martha N. Kivecu, Edwin W. Mwakio, Gladys C. Chemwor, Redempta A. Yeda, Agnes C. Cheruiyot, Jackline A. Juma, Charles O. Okello
Publikováno v:
F1000Research, Vol 9 (2022)
Background: The emergence of artemisinin resistance in South East Asia calls for urgent discovery of new drug compounds that have antiplasmodial activity. Unlike the classical compound screening drug discovery methods, the rational approach involving
Externí odkaz:
https://doaj.org/article/3bfdfb6ffe72483bbaeeac0f7421e1cf
Autor:
Douglas O. Ochora, Esezah K. Kakudidi, Jane Namukobe, Perpetua Ipulet, Dancan M. Wakoli, Winnie Okore, Edwin W. Mwakio, Redempthah A. Yeda, Agnes C. Cheruiyot, Dennis W. Juma, Ben Andagalu, Amanda L. Roth, Bernhards R. Ogutu, Abiy Yenesew, Hoseah M. Akala
Publikováno v:
Plants, Vol 11, Iss 1, p 47 (2021)
Malaria is the most lethal parasitic disease in the world. The frequent emergence of resistance by malaria parasites to any drug is the hallmark of sustained malaria burden. Since the deployment of artemisinin-based combination therapies (ACTs) it is
Externí odkaz:
https://doaj.org/article/27b43c3627354952ad059357c663a37f
Publikováno v:
Viruses, Vol 10, Iss 11, p 617 (2018)
A potential concern with bacteriophage (phage) therapeutics is a host-versus-phage response in which the immune system may neutralize or destroy phage particles and thus impair therapeutic efficacy, or a strong inflammatory response to repeated phage
Externí odkaz:
https://doaj.org/article/25f02dd8bca4447c8d3752a150b14f76
Autor:
Gladys C. Chemwor, Ben M. Andagalu, Irene A. Onyango, Benjamin H. Opot, Raphael O. Okoth, Redemptah A. Yedah, Jackline A. Juma, Edwin W. Mwakio, Wakoli M. Duncan, Joseph G. Amwoma, Agnes C. Cheruiyot, Dennis W. Juma, Timothy E. Egbo, Eric C. Garges, Amanda L. Roth, Edwin A. Kamau, Bernhards Ogutu, Oliver J. Watson, Hoseah Akala
Publikováno v:
SSRN Electronic Journal.
Autor:
Steffanie L Solberg, Helen Crouch, Christopher Florez, Alice E Barsoumian, Tamara S Funari, Ashley S Hanhurst, Amanda L Roth, Clinton K. Murray
Publikováno v:
Military Medicine. 185:e818-e824
Introduction Up to 34% of combat trauma injuries are complicated by infection with multidrug-resistant organisms. Overutilization of antibiotics has been linked to increased multidrug-resistant organisms in combat-injured patients. Antimicrobial stew
Autor:
Jennifer M. Mutisya, Victor A. Mobegi, Johnson K. Kinyua, Martha N. Kivecu, Raphael O. Okoth, Gladys C. Chemwor, Edwin W. Mwakio, Agnes C. Cheruiyot, Redempta A. Yeda, Charles O. Okello, Jackline A. Juma, Benjamin H. Opot, Dennis W. Juma, Amanda L. Roth, Hosea M. Akala, Ben M. Andagalu
Publikováno v:
F1000Research. 9:1268
Background: The emergence of artemisinin resistance in South East Asia calls for urgent discovery of new drug compounds that have antiplasmodial activity. Unlike the classical compound screening drug discovery methods, the rational approach involving
Autor:
Douglas O. Ochora, Paolo Coghi, Vincent Kam Wai Wong, Edwin W. Mwakio, Matthias Heydenreich, Amanda L. Roth, Esezah Kakudidi, Li Jun Yang, Abiy Yenesew, Ben Andagalu, Jane Namukobe, Hoseah M. Akala
Extracts from Securidaca longipedunculata showed antiplasmodial activities against reference clones and clinical isolates using SYBR Green I method. A new benzophenone, 2,3,4,5-tetramethoxybenzophenone (1) was isolated and characterized along with se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4d892065f6a5fc473294f96ac15ae2
Autor:
Jennifer M, Mutisya, Victor A, Mobegi, Johnson K, Kinyua, Martha N, Kivecu, Raphael O, Okoth, Gladys C, Chemwor, Edwin W, Mwakio, Agnes C, Cheruiyot, Redempta A, Yeda, Charles O, Okello, Jackline A, Juma, Benjamin H, Opot, Dennis W, Juma, Amanda L, Roth, Hosea M, Akala, Ben M, Andagalu
Publikováno v:
F1000Research. 9