Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Amanda L, Johnson"'
Autor:
Amanda L. Johnson, Sonia S. Elder, John G. McKendrick, Lizi M. Hegarty, Ella Mercer, Elaine Emmerson
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/60d13ab2802742ffa72c73d92bf0b925
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The current median survival for glioblastoma (GBM) patients is only about 16 months, with many patients succumbing to the disease in just a matter of months, making it the most common and aggressive primary brain cancer in adults. This poor outcome i
Externí odkaz:
https://doaj.org/article/79ddda6b0fa9404fb7a201e22fb63f43
Use of a Novel Hypercrosslinked Carbohydrate Scaffold for Vocal Fold Medialization in an Ovine Model
Publikováno v:
OTO Open, Vol 7, Iss 4, Pp n/a-n/a (2023)
Abstract Objectives Vocal fold medialization is commonly performed for glottic insufficiency and vocal fold immobility. Currently available materials are temporary injectables or synthetic implants. Acellular scaffolds may allow vocal fold augmentati
Externí odkaz:
https://doaj.org/article/bf489bbbc017480f86649ae1a0b39cda
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Despite its growing use in cancer treatment, immunotherapy has been virtually ineffective in clinical trials for gliomas. The inherently cold tumor immune microenvironment (TIME) in gliomas, characterized by a high ratio of pro-tumor to anti-tumor im
Externí odkaz:
https://doaj.org/article/5cf6b9a7d58a4246a2ecba8d6af7169f
Publikováno v:
Cells, Vol 12, Iss 15, p 1968 (2023)
Skeletal muscle has a high capacity to repair and remodel in response to damage, largely through the action of resident muscle stem cells, termed satellite cells. Satellite cells are required for the proper repair of skeletal muscle through a process
Externí odkaz:
https://doaj.org/article/67bf30e6df6c443c90e9a3c1578828f1
Autor:
Larry S. Sherman, Weiping Su, Amanda L. Johnson, Samuel M. Peterson, Cassandra Cullin, Tiffany Lavinder, Betsy Ferguson, Anne D. Lewis
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105465- (2021)
Pelizaeus-Merzbacher disease (PMD) is a severe hypomyelinating disorder of the central nervous system (CNS) linked to mutations in the proteolipid protein-1 (PLP1) gene. Although there are multiple animal models of PMD, few of them fully mimic the hu
Externí odkaz:
https://doaj.org/article/2d2d3e20c3af4b85b3ae0e3f5c95a2cb
Autor:
Matthew G. McDonald, Catherine K. Yeung, Aaron M. Teitelbaum, Amanda L. Johnson, Shinya Fujii, Hiroyuki Kagechika, Allan E. Rettie
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 4, Pp 892-899 (2019)
Vitamin K (VK), in both its phylloquinone and menaquinone forms, has been hypothesized to undergo ω- and β-oxidation on its hydrophobic side chain in order to generate the observed urinary metabolites, K acid I and K acid II, which are excreted pri
Externí odkaz:
https://doaj.org/article/f76ce9485fad4bcdba19644badf8ed00
Autor:
John G. McKendrick, Gareth-Rhys Jones, Sonia S. Elder, Ella Mercer, Marlene S. Magalhaes, Cecilia Rocchi, Lizi M. Hegarty, Amanda L. Johnson, Christoph Schneider, Burkhard Becher, Clare Pridans, Neil Mabbott, Zhaoyuan Liu, Florent Ginhoux, Marc Bajenoff, Rebecca Gentek, Calum C. Bain, Elaine Emmerson
The salivary glands often become damaged in individuals receiving radiotherapy for head and neck cancer, resulting in xerostomia, or chronic dry mouth. This leads to detrimental effects on their health and quality of life, for which there is no regen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f4535b51b09e73c3110ed64f3d6510
https://doi.org/10.1101/2022.06.12.495803
https://doi.org/10.1101/2022.06.12.495803
Synthesis and Evaluation of Functionalized Aryl and Biaryl Isothiocyanates against Human MCF‐7 Cells
Autor:
Claire C. Fanta, Kaitlyn J. Tlusty, Sarah E. Pauley, Amanda L. Johnson, Genevieve A. Benjamin, Taylor K. Yseth, Michaela M. Bunde, Paul T. Pierce, Shirley Wang, Peter F. Vitiello, Jared R. Mays
Publikováno v:
ChemMedChem. 17
Organic isothiocyanates (ITCs) are a class of anticancer agents which naturally result from the enzymatic degradation of glucosinolates produced by Brassica vegetables. Previous studies have demonstrated that the structure of an ITC impacts its poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfea5298fe62565965b813dbeff8259f
https://doi.org/10.1002/cmdc.202200250
https://doi.org/10.1002/cmdc.202200250
Publikováno v:
Journal of the American Association for Laboratory Animal Science. 60:329-336
Subcutaneous injection site reactions to sustained-release buprenorphine hydrochloride (Buprenorphine SR) in macaques have been reported in only a single case report. In the current study, we evaluated the incidence rate and predictors of buprenorphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d82da41a9cf15d43492d67d2b5e70b3
https://doi.org/10.30802/aalas-jaalas-20-000118
https://doi.org/10.30802/aalas-jaalas-20-000118