Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Amanda Kirkham"'
Autor:
Gideon M. Hirschfield, Katherine Arndtz, Amanda Kirkham, Yung-Yi Chen, Richard Fox, Anna Rowe, Jessica Douglas-Pugh, Douglas Thorburn, Eleanor Barnes, Guruprasad P. Aithal, Diana Hull, Khushpreet Bhandal, Kathryn Olsen, Paul Woodward, Siân Lax, Philip Newsome, David J. Smith, Antero Kallio, David H. Adams, Victoria Homer, Chris J. Weston
Publikováno v:
Hepatology Communications, Vol 8, Iss 5 (2024)
Background:. Primary sclerosing cholangitis is a progressive inflammatory liver disease characterized by biliary and liver fibrosis. Vascular adhesion protein-1 (VAP-1) is important in the inflammatory process driving liver fibrosis. We evaluated the
Externí odkaz:
https://doaj.org/article/1b222fe6ac3c4e409c92ca04f98f474a
Autor:
Julia Chisholm, Henry Mandeville, Madeleine Adams, Veronique Minard-Collin, Timothy Rogers, Anna Kelsey, Janet Shipley, Rick R. van Rijn, Isabelle de Vries, Roelof van Ewijk, Bart de Keizer, Susanne A. Gatz, Michela Casanova, Lisa Lyngsie Hjalgrim, Charlotte Firth, Keith Wheatley, Pamela Kearns, Wenyu Liu, Amanda Kirkham, Helen Rees, Gianni Bisogno, Ajla Wasti, Sara Wakeling, Delphine Heenen, Deborah A. Tweddle, Johannes H. M. Merks, Meriel Jenney
Publikováno v:
Cancers, Vol 16, Iss 5, p 998 (2024)
The Frontline and Relapsed Rhabdomyosarcoma (FaR-RMS) clinical trial is an overarching, multinational study for children and adults with rhabdomyosarcoma (RMS). The trial, developed by the European Soft Tissue Sarcoma Study Group (EpSSG), incorporate
Externí odkaz:
https://doaj.org/article/2d171c4564c54dfba3bfaef91bcef0d6
Autor:
Katherine Arndtz, Yung-Yi Chen, Anna Rowe, Victoria Homer, Amanda Kirkham, Jessica Douglas-Pugh, Daniel Slade, Douglas Thorburn, Eleanor Barnes, Guruprasad Aithal, Philip Newsome, David Smith, David Adams, Christopher Weston, Gideon Hirschfield
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 9, Iss 1 (2022)
Background: Primary sclerosing cholangitis is a progressive and fibrotic liver disease. Treatments remain inadequate, and patients with persistent elevations in activity of alkaline phosphatase are at greatest risk of disease progression. Studies in
Externí odkaz:
https://doaj.org/article/3861c15d56054a6882cf103a0170f68a
Autor:
Stuart A. McIntosh, Charlotte E. Coles, David Dodwell, Kenneth Elder, Jessica Foster, Claire Gaunt, Amanda Kirkham, Iain Lyburn, Jenna Morgan, Sangeetha Paramasivan, Sarah E. Pinder, Sarah Pirrie, Shelley Potter, Tracy Roberts, Nisha Sharma, Hilary Stobart, Elizabeth Southgate, Sian Taylor-Phillips, Matthew Wallis, Daniel Rea
Publikováno v:
Cancer Research. 83:OT3-20
Background: Mammographic screening programmes reduce breast cancer mortality, but detect many small tumours with favourable biological features which may not progress during a woman’s lifetime. Screen-detected cancers are treated with standard surg
Autor:
Isaac Nay, Doug Hutchinson, Matthew Rondina, Kibum Kim, Rachel Kroencke, Amanda Kirkham, Toby Trujillo, Neal D. Tolley, Mark Munger
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 43:215-225
Autor:
Stuart A McIntosh, Charlotte E Coles, Carmel Conefrey, David Dodwell, Kenneth Elder, Jessica Foster, Claire Gaunt, Amanda Kirkham, Iain Lyburn, Jenna Morgan, Sangeetha Paramasivan, Sarah Pinder, Sarah Pirrie, Shelley Potter, Tracy Roberts, Nisha Sharma, Hilary Stobart, Elizabeth Southgate, Sian Taylor-Phillips, Matthew Wallis, Daniel Rea
Publikováno v:
Cancer Research. 82:OT1-06
Background:. Mammographic screening programmes have been shown to reduce breast cancer mortality. However, they detect many small tumours with favourable biological features which may not progress during a woman’s lifetime. These are treated with s
Autor:
Rachel Phillips, Suzie Cro, Graham Wheeler, Simon Bond, Tim P Morris, Siobhan Creanor, Catherine Hewitt, Sharon Love, Andre Lopes, Iryna Schlackow, Carrol Gamble, Graeme MacLennan, Chris Habron, Anthony C Gordon, Nikhil Vergis, Tianjing Li, Riaz Qureshi, Colin C Everett, Jane Holmes, Amanda Kirkham, Clare Peckitt, Sarah Pirrie, Norin Ahmed, Laura Collett, Victoria Cornelius
Publikováno v:
BMJ (Clinical research ed.). 377
ObjectiveTo improve communication of harm in publications of randomised controlled trials via the development of recommendations for visually presenting harm outcomes.DesignConsensus study.Setting15 clinical trials units registered with the UK Clinic
Autor:
Stuart A. McIntosh, Charlotte E. Coles, David Dodwell, Kenneth Elder, Jessica Foster, Claire Gaunt, Amanda Kirkham, Iain Lyburn, Jenna Morgan, Sarah E. Pinder, Sarah Pirrie, Shelley Potter, Tracy Roberts, Nisha Sharma, Hilary Stobart, Elizabeth Southgate, Sian Taylor-Phillips, Matthew Wallis, Daniel Rea, Sangeetha Paramasivan
Publikováno v:
Cancer Research. 83:P6-05
Background SMALL (ISRCTN 12240119) is a novel UK phase III multicentre randomised trial comparing vacuum-assisted excision (VAE) to surgery for small screen-detected breast cancers with biologically favourable characteristics. Acceptance by the clini
Autor:
Stuart McIntosh, Charlotte E. Coles, Carmel Conefrey, David John Dodwell, Jessica Foster, Claire Gaunt, Amanda Kirkham, Iain Lyburn, Jenna Morgan, Sangeetha Paramasivan, Sarah E. Pinder, Sarah Pirrie, Shelley Potter, Tracy Roberts, Nisha Sharma, Hilary Stobart, Elizabeth Southgate, Sian Taylor-Phillips, Matthew Wallis, Dan Rea
Publikováno v:
Journal of Clinical Oncology. 40:TPS614-TPS614
TPS614 Background: Mammographic screening programmes reduce breast cancer mortality but detect many small tumours with favourable biology which may not progress. These are treated with surgery and adjuvant therapies, but associated morbidities mean t
Autor:
Thomas Marjot, Pamela Kearns, Ana Hughes, Thushan I de Silva, Michelle Willicombe, Sarah Pirrie, Amanda Kirkham, Georgina Meacham, Daniel Rea, Stefan Siebert, Sophie L. Irwin, Susanna Dunachie, Lance Turtle, Sophia Magwaro, Zixiang Lim, Carl S. Goodyear, David B. Thomas, Stavros I. Dimitriadis, Alex G. Richter, Jack Satsangi, Charlotte Gaskell, Iain B. McInnes, Peter Kelleher, Paul B. Miller, Eleanor Barnes, Sarah Bowden, Zay Win, Neil Basu, Paul Klenerman, Gordon Cook, Sam M. Murray
Publikováno v:
SSRN Electronic Journal.
SARS-COV-2 vaccines have been shown to be efficacious primarily in healthy volunteer populations and population level studies. Immune responses following SARS-CoV-2 vaccination are less well characterised in potentially immune vulnerable patient grou