Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Amanda K. Wiggins"'
Autor:
Amanda K. Wiggins, Wai Y. Chan, Sang Won Suh, Eric J. Huang, Raymond A. Swanson, Tiina M. Kauppinen
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7136-7141
Sustained activation of poly(ADP-ribose) polymerase-1 (PARP-1) and extracellular signal-regulated kinases 1/2 (ERK1/2) both promote neuronal death. Here we identify a direct link between these two cell death pathways. In a rat model of hypoglycemic b
Publikováno v:
Journal of Neurochemistry. 87:1368-1380
Cortical spreading depression (CSD) is characterized by slowly propagating waves of neuronal/astrocytic depolarization and metabolic changes, followed by a period of quiescent neuronal and electroencephalographic activity. CSD acts as a preconditioni
Publikováno v:
Molecular Brain Research. 114:20-30
Clusterin is a sulfated glycoprotein produced by neurons and by resting and activated astrocytes that has several putative functions, including protective responses to brain injury. Cortical spreading depression (CSD) is a powerful yet largely benign
Autor:
Eric J. Huang, Huashun Li, Rachael L. Neve, Lily Yeh Jan, Yuh Nung Jan, Amy A. Tang, Weimin Zhong, Amanda K. Wiggins
Publikováno v:
Genesdevelopment. 19(1)
Mouse Numb homologs antagonize Notch1 signaling pathways through largely unknown mechanisms. Here we demonstrate that conditional mouse mutants with deletion of numb and numblike in developing sensory ganglia show a severe reduction in axonal arboriz
Autor:
Amanda K. Wiggins, Rachael L. Neve, Eric J. Huang, Keling Zang, Connie Wong, Esther J. Luo, Amy A. Tang, Louis F. Reichardt, Guangwei Wei, Epaminondas Doxakis
Publikováno v:
The Journal of Cell Biology
The Pit1-Oct1-Unc86 domain (POU domain) transcription factor Brn3a controls sensory neuron survival by regulating the expression of Trk receptors and members of the Bcl-2 family. Loss of Brn3a leads to a dramatic increase in apoptosis and severe loss
Publikováno v:
Journal of neurochemistry. 87(6)
Cortical spreading depression (CSD) is characterized by slowly propagating waves of neuronal/astrocytic depolarization and metabolic changes, followed by a period of quiescent neuronal and electroencephalographic activity. CSD acts as a preconditioni
Publikováno v:
Journal of Neurochemistry; 12/15/2003, Vol. 87 Issue 6, p1368-1380, 13p