Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amanda K. F. Oxbrow"'
Autor:
Lindsay K. Shuttleworth, Andrew J. Beavil, Amanda K. F. Oxbrow, Alistair James Henry, Michael W-P Kao, James M. McDonnell, Benjamin P. Cossins, Jean Delgado, Hanna Hailu, Michael John Wright, Nyssa Drinkwater, Brian J. Sutton, Katharine Cain, Anthony H. Keeble
Publikováno v:
Nature structural & molecular biology
Crystallographic and solution studies have shown that IgE molecules are acutely bent in their Fc region. Crystal structures reveal the Cɛ2 domain pair folded back onto the Cɛ3-Cɛ4 domains, but is the molecule exclusively bent or can the Cɛ2 domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4283914b99886c6d46916dd391611eab
http://europepmc.org/articles/PMC3977038
http://europepmc.org/articles/PMC3977038
Autor:
Amanda S. Cross, Brendon MacKenzie, Louis Christodoulou, James T. Heads, Carl Brendan Doyle, Matthew Page, Hanna Hailu, Karine Jeannine Madeleine Hervé, Mark Ellis, Sarah L. Dugdale, Victoria O’Dowd, Nicola L. Davies, Alison Turner, Daniel John Lightwood, Adrian Moore, David Edward Ormonde Knight, Marco Kriek, Kaushik Sarkar, Mark Jairaj, David P. Humphreys, Matthew Cox, Kerry Louise Tyson, Joanne E. Compson, Amanda K. F. Oxbrow
Publikováno v:
Clinical and Vaccine Immunology. 20:377-390
Clostridium difficile infections are a major cause of antibiotic-associated diarrhea in hospital and care facility patients. In spite of the availability of effective antibiotic treatments, C. difficile infection (CDI) is still a major cause of patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502a01b494632943b9983cbcfab8a7ed
https://doi.org/10.1128/cvi.00625-12
https://doi.org/10.1128/cvi.00625-12
Autor:
B. Dhaliwal, Amanda K. F. Oxbrow, Brian J. Sutton, Daopeng Yuan, Stella M. Fabiane, James M. McDonnell, Katharine Cain, Marie O. Y. Pang, Andrew J. Beavil, Hannah J. Gould, Alistair James Henry
Publikováno v:
Proceedings of the National Academy of Sciences. 109:12686-12691
The role of IgE in allergic disease mechanisms is performed principally through its interactions with two receptors, FcεRI on mast cells and basophils, and CD23 (FcεRII) on B cells. The former mediates allergic hypersensitivity, the latter regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebcd416e7d7442b445361cb34169f1f
https://doi.org/10.1073/pnas.1207278109
https://doi.org/10.1073/pnas.1207278109