Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amanda Jurgelewicz"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is associated with metabolic syndrome (MetS) in humans and elicits pathologies in rodents that resemble non-alcoholic fatty liver disease (NAFLD) in humans through activation of the aryl hydrocarbon
Externí odkaz:
https://doaj.org/article/6ca555dc30684b499a04f452103b3251
Autor:
David W. Threadgill, Peter Dornbos, Rance Nault, Amanda Jurgelewicz, Melanie Warren, Hui Lin, Anooj A Arkatkar, Timothy R. Zacharewski, John J. LaPres
Publikováno v:
Toxicol Sci
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor in the Per-Arnt-Sim superfamily of environmental sensors that is linked to several metabolic diseases, including nonalcoholic fatty liver disease. Much remains unknown reg
Autor:
Peter Dornbos, John J. LaPres, Kelly A. Fader, Kurt J. Williams, Amanda Jurgelewicz, Timothy R. Zacharewski
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor. The prototypical ligand of the AHR is an environmental contaminant called 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD exposure is associated with many adverse health