Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Amanda Jane Tristram"'
Autor:
Samantha Jayne Hibbitts, Ned George Powell, Alison Nina Fiander, Dean Bryant, Sadie Jones, Amanda Jane Tristram, Chris Nicholas Hurt
Publikováno v:
Clinical Cancer Research. 23:5460-5468
Purpose: Response rates to treatment of vulval intraepithelial neoplasia (VIN) with imiquimod and cidofovir are approximately 57% and 61%, respectively. Treatment is associated with significant side effects and, if ineffective, risk of malignant prog
Autor:
Maribel Almonte, Samantha Jayne Hibbitts, Amanda Jane Tristram, Ned George Powell, Dean Bryant, Alison Nina Fiander
Publikováno v:
Journal of Clinical Virology. 66:66-71
Background Persistent infection with human papillomavirus (HPV) type 16 causes the majority of cervical cancers. Genital HPV infection is very common, but neoplastic progression is uncommon. There is an urgent need for biomarkers associated with cerv
Autor:
Rachel Raybould, Sadie Jones, Tiffany Onions, Ned George Powell, Dean Bryant, Amanda Jane Tristram, Alison Nina Fiander, Samantha Jayne Hibbitts
Publikováno v:
Journal of Clinical Virology. 61:393-399
Background: Methylation of HPV16 DNA is a promising biomarker for triage of HPV positive cervical screening samples but the biological basis for the association between HPV-associated neoplasia and increased methylation is unclear. Objectives: To det
Autor:
Peter Dutton, Andrew J. Nordin, Sam Hibbitts, Gareth Griffiths, Stephen Man, Sadie Jones, Raj Naik, Ned George Powell, Alison Nina Fiander, Tracie Madden, Chris Nicholas Hurt, Amanda Jane Tristram
Publikováno v:
The Lancet Oncology. 15(12):1361-1368
Summary Background Vulval intraepithelial neoplasia is a skin disorder affecting the vulva that, if left untreated, can become cancerous. Currently, the standard treatment for patients with vulval intraepithelial neoplasia is surgery, but this approa
Autor:
Áine Sinéad Flynn, Alison Nina Fiander, Rachel Raybould, Dean Bryant, Kevin E. Ashelford, Tiffany Onions, Amanda Jane Tristram, Peter Giles, Samantha Jayne Hibbitts, Ned George Powell, Sian Meyrick
Publikováno v:
Journal of Medical Virology. 86:1534-1541
Vulval intraepithelial neoplasia is a precursor of vulval cancer and is commonly caused by infection with Human Papillomavirus (HPV). Development of topical treatments for vulval intraepithelial neoplasia requires appropriate in vitro models. This st
Autor:
Samantha Jayne Hibbitts, Anne Hildegard Hauke, Nick Dallimore, Robert G. Newcombe, Jane McRea, H. Beer, Alison Nina Fiander, Bryan Rose, Dave Nuttall, Amanda Jane Tristram
Publikováno v:
Journal of Clinical Virology. 59:109-114
Background: In 2008 a human papillomavirus (HPV) vaccination programme for cervical cancer prevention was implemented in the UK. Surveillance of vaccine uptake, impact on prevalence of HPV infection and cervical cancer incidence were identified as ke
Publikováno v:
The Obstetrician & Gynaecologist. 15:221-226
Key content Human papillomavirus (HPV) is associated with neoplastic disease at sites other than the cervix. Cancer caused by HPV may behave differently to other cancers at the same site. The presence of HPV alone is not sufficient to demonstrate a c
Autor:
Amanda Jane Tristram
Publikováno v:
British Journal of Cancer
Background: Human papillomavirus (HPV) testing is more sensitive than cytology for detecting high-grade cervical intraepithelial neoplasia (CIN). We evaluated the performance of high-risk HPV (hrHPV) testing in routine screening. Methods: In all, 25
Autor:
Azka Saleem, Kate Gregory, Samantha Jayne Hibbitts, T. S. Shylasree, Ned George Powell, Nima Rai, Suzanne Ashman, Amanda Jane Tristram, Alison Nina Fiander, Joanne Jones
Publikováno v:
Journal of Clinical Virology. 52:88-92
Background Human Papillomavirus (HPV) testing has been evaluated as a test of cure in patients following treatment of high-grade cervical intraepithelial neoplasia (CIN2+). Studies show that women who are HPV and cytology negative post treatment can
Autor:
Samantha Jayne Hibbitts, Ned George Powell, Alison Nina Fiander, Joanne Jones, Amanda Jane Tristram
Publikováno v:
Journal of Clinical Virology. 45:100-104
Background Cervical screening detects precancerous cells and routine screening could be improved by testing for Human Papillomavirus (HPV), the virus that causes cervical cancer. HPV infection is common and the benefit of HPV testing would be identif