Chemokines form complex signals during inflammation and disease that can be decoded by extracellular matrix proteoglycans

Autor: Amanda JL Ridley, Yaqing Ou, Richard Karlsson, Nabina Pun, Holly L Birchenough, Thomas A Jowitt, Craig Lawless, Rebecca L Miller, Douglas P Dyer

Chemokine driven leukocyte recruitment is a key component of the immune response and is central to a wide range of diseases. However, there has yet to be a clinically successful therapeutic approach that targets the chemokine system during inflammato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::245a772df5d8f80f5dcc92cbb0c64d4c
https://doi.org/10.1101/2022.09.20.508420

Chemokine redundancy versus specificity in the context of CXCR3 and its ligands

Autor: Amanda JL Ridley, Douglas P Dyer

Publikováno v: Ridley, A J & Dyer, D P 2022, ' Chemokine redundancy versus specificity in the context of CXCR3 and its ligands ', Immunology and cell biology, vol. 100, no. 6, pp. 387-389 . https://doi.org/10.1111/imcb.12553

In a recent article published in Immunology & Cell Biology, Dalit et al. describe how correcting mutations in the C57BL/6 mouse strain can restore production of the chemokine CXCL11, although surprisingly, this expression of CXCL11 had little effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb8e941462967503928d771b99bf490
https://www.research.manchester.ac.uk/portal/en/publications/chemokine-redundancy-versus-specificity-in-the-context-of-cxcr3-and-its-ligands(759ad280-b58d-4bff-bbae-37d90aee3f28).html