Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Amanda J. Wood"'
Autor:
Jillian McEwan, Reza J. Rasoulpour, B. Bhaskar Gollapudi, Amanda J. Wood, David R. Geter, Audrey Vardy, Matthew J. LeBaron, Jennifer A. Murray, Claire Terry, Johnson Thomas, Cliff Elcombe, Richard Billington, H. Lynn Kan
Publikováno v:
Toxicology and Applied Pharmacology. 270:164-173
Registration of new plant protection products (e.g., herbicide, insecticide, or fungicide) requires comprehensive mammalian toxicity evaluation including carcinogenicity studies in two species. The outcome of the carcinogenicity testing has a signifi
Autor:
Michael J. Bartels, B. Bhaskar Gollapudi, Melissa R. Schisler, Amanda J. Wood, Fagen Zhang, Yo-Chan Jeong, David R. Geter
Publikováno v:
Toxicology Letters. 214:226-233
Adenosine deaminases (ADA) are key enzymes that deaminate adenosine (A) or deoxyadenosine (dA) and produce inosine or deoxyinosine (dI), respectively. While ADA only deaminates free dA, reactive nitrogen species (RNS) or reactive oxygen species (ROS)
Autor:
Amanda J. Wood, Yo-Chan Jeong, David R. Geter, Lisa G. McFadden, Michael J. Bartels, H. Lynn Kan, Fagen Zhang, Melissa R. Schisler, B. Bhaskar Gollapudi
Publikováno v:
Toxicology mechanisms and methods. 22(7)
Depletion of glutathione (GSH) in cells exposed to certain xenobiotics has been proposed to result in oxidative stress, which could lead to damage of cellular macromolecules such as proteins, lipids, and DNA. Diethyl maleate (DEM) is known to conjuga
Autor:
Yo-Chan Jeong, Fagen Zhang, B. Bhaskar Gollapudi, Michael J. Bartels, Lynn Kan, David R. Geter, Amanda J. Wood, Melissa R. Schisler
Publikováno v:
Rapid communications in mass spectrometry : RCM. 22(22)
Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine. It is present in practically all cells and has several important roles, such as preventing the oxidation of the sulfhydryl groups of proteins within a cell. Evidence for