Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Amanda J. Russell"'
Autor:
Jayne E. Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J. Gifford, Jamie I. Fletcher, Chengyuan Xue, Nisitha Jayatilleke, Firoozeh Salehzadeh, Laura D. Gamble, Jourdin R. C. Rouaen, Daniel R. Carter, Helen Forgham, Eric O. Sekyere, Joanna Keating, Georgina Eden, Sophie Allan, Stephanie Alfred, Frances K. Kusuma, Ashleigh Clark, Hannah Webber, Amanda J. Russell, Antoine de Weck, Benjamin T. Kile, Martina Santulli, Piergiuseppe De Rosa, Emmy D. G. Fleuren, Weiman Gao, Lorna Wilkinson-White, Jason K. K. Low, Joel P. Mackay, Glenn M. Marshall, Douglas J. Hilton, Federico M. Giorgi, Jan Koster, Giovanni Perini, Michelle Haber, Murray D. Norris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract MYCN oncogene amplification is frequently observed in aggressive childhood neuroblastoma. Using an unbiased large-scale mutagenesis screen in neuroblastoma-prone transgenic mice, we identify a single germline point mutation in the transcript
Externí odkaz:
https://doaj.org/article/ee532e0c05a8415d9de099a04d9f475c
Autor:
Jixuan Gao, MoonSun Jung, Rebekka T. Williams, Danica Hui, Amanda J. Russell, Andrea J. Naim, Alvin Kamili, Molly Clifton, Angelika Bongers, Chelsea Mayoh, Gwo Ho, Clare L. Scott, Wendy Jessup, Michelle Haber, Murray D. Norris, Michelle J. Henderson, on behalf of Australian Ovarian Cancer Study
Publikováno v:
Cancers, Vol 14, Iss 8, p 1878 (2022)
Background: Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy with over 80% of cases already disseminated at diagnosis and facing a dismal five-year survival rate of 35%. EOC cells often spread to the greater omentum where
Externí odkaz:
https://doaj.org/article/309943b0c0a94d9d915568cbc9872776
Autor:
Laura D. Gamble, Stefania Purgato, Michelle J. Henderson, Simone Di Giacomo, Amanda J. Russell, Paolo Pigini, Jayne Murray, Emanuele Valli, Giorgio Milazzo, Federico M. Giorgi, Mark Cowley, Lesley J. Ashton, Jaydutt Bhalshankar, Gudrun Schleiermacher, Ali Rihani, Tom Van Maerken, Jo Vandesompele, Frank Speleman, Rogier Versteeg, Jan Koster, Angelika Eggert, Rosa Noguera, Raymond L. Stallings, Gian Paolo Tonini, Kwun Fong, Zalman Vaksman, Sharon J. Diskin, John M. Maris, Wendy B. London, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Giovanni Perini, Murray D. Norris, Michelle Haber
Publikováno v:
Cancers, Vol 13, Iss 8, p 1807 (2021)
Ornithine decarboxylase (ODC1), a critical regulatory enzyme in polyamine biosynthesis, is a direct transcriptional target of MYCN, amplification of which is a powerful marker of aggressive neuroblastoma. A single nucleotide polymorphism (SNP), G316A
Externí odkaz:
https://doaj.org/article/d53bfb862d414aec9d647c76d3457b58
Autor:
Michelle J. Henderson, Murray D. Norris, Michelle Haber, Jamie I. Fletcher, Wendy B. London, André Oberthuer, David D.L. Bowtell, Anna DeFazio, Tao Liu, Pei Yan Liu, Joshy George, Bing Liu, Amanda J. Russell, MoonSun Jung
A list of cancer cell lines and culture conditions (S1); Clinicopathological characteristics of primary neuroblastoma cohort (S2); Taqman gene expression assay IDs (S3); Gene Ontology biological process terms for the 18 Myc activity signature genes (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87b0f8b076b19bbb95e02178a5bfb7c
https://doi.org/10.1158/0008-5472.22411122.v1
https://doi.org/10.1158/0008-5472.22411122.v1
Autor:
Michelle J. Henderson, Murray D. Norris, Michelle Haber, Jamie I. Fletcher, Wendy B. London, André Oberthuer, David D.L. Bowtell, Anna DeFazio, Tao Liu, Pei Yan Liu, Joshy George, Bing Liu, Amanda J. Russell, MoonSun Jung
Myc transcriptional activity is frequently deregulated in human cancers, but a Myc-driven gene signature with prognostic ability across multiple tumor types remains lacking. Here, we selected 18 Myc-regulated genes from published studies of Myc famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d84b5adbfc7479ae3675f7c54b1640e
https://doi.org/10.1158/0008-5472.c.6508161.v1
https://doi.org/10.1158/0008-5472.c.6508161.v1
Autor:
Michelle J. Henderson, Murray D. Norris, Michelle Haber, Jamie I. Fletcher, Wendy B. London, André Oberthuer, David D.L. Bowtell, Anna DeFazio, Tao Liu, Pei Yan Liu, Joshy George, Bing Liu, Amanda J. Russell, MoonSun Jung
Comparison of MYCN and MYC expression levels between MYCN amplified and non-MYCN amplified (non-MNA) neuroblastomas (S1); Prognostic significance of MYCN and MYC genes in non-MYCN amplified neuroblastoma (S2); Relationship between signature score and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8b01b037b12764f93d5352f56e0992
https://doi.org/10.1158/0008-5472.22411125
https://doi.org/10.1158/0008-5472.22411125
Autor:
Michelle J. Henderson, Murray D. Norris, Michelle Haber, Jamie I. Fletcher, Wendy B. London, André Oberthuer, David D.L. Bowtell, Anna DeFazio, Tao Liu, Pei Yan Liu, Joshy George, Bing Liu, Amanda J. Russell, MoonSun Jung
Legends for Supplementary Figures S1-S5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125f006ad836c8d53dd879ee7298ef01
https://doi.org/10.1158/0008-5472.22411128.v1
https://doi.org/10.1158/0008-5472.22411128.v1
Autor:
Karen L. MacKenzie, Jamie I. Fletcher, Giovanni Perini, Murray D. Norris, Preethi H. Gunaratne, Michelle Haber, Wendy B. London, Hilda A. Pickett, Georg von Jonquieres, Claudia L. Flemming, Amanda J. Russell, Jayne Murray, Chen Yang, Stefania Purgato, Cheng Fei Kong, Bing Liu, Michelle F. Maritz, Sieu L. Tran, Rosemary O'Brien
Supplementary Table 1: siRNA sequences Supplementary Table 2: qRT-PCR primers Supplementary Table 3: Primers for chromatin immunoprecipitation Supplementary Table 4: Multivariate analysis of event free survival and overall survival of neuroblastoma p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3ec84b0ce4a494d58db2967c5528d5
https://doi.org/10.1158/0008-5472.22410269.v1
https://doi.org/10.1158/0008-5472.22410269.v1
Autor:
Karen L. MacKenzie, Jamie I. Fletcher, Giovanni Perini, Murray D. Norris, Preethi H. Gunaratne, Michelle Haber, Wendy B. London, Hilda A. Pickett, Georg von Jonquieres, Claudia L. Flemming, Amanda J. Russell, Jayne Murray, Chen Yang, Stefania Purgato, Cheng Fei Kong, Bing Liu, Michelle F. Maritz, Sieu L. Tran, Rosemary O'Brien
Supporting data; Supplementary Figure 1:Correlation analysis of DKC1 mRNA and dyskerin protein quantity in neuroblastoma cell lines Supplementary Figure 2:Correlation analysis of telomerase activity gene expression in neuroblastoma cells Supplementar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794cfbdb3bcad0e4b5ee232834ca8996
https://doi.org/10.1158/0008-5472.22410275.v1
https://doi.org/10.1158/0008-5472.22410275.v1
Autor:
Karen L. MacKenzie, Jamie I. Fletcher, Giovanni Perini, Murray D. Norris, Preethi H. Gunaratne, Michelle Haber, Wendy B. London, Hilda A. Pickett, Georg von Jonquieres, Claudia L. Flemming, Amanda J. Russell, Jayne Murray, Chen Yang, Stefania Purgato, Cheng Fei Kong, Bing Liu, Michelle F. Maritz, Sieu L. Tran, Rosemary O'Brien
Text file containing detailed methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d0ed20dbd1ebc233186422ff2edeb1
https://doi.org/10.1158/0008-5472.22410272.v1
https://doi.org/10.1158/0008-5472.22410272.v1