Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amanda J. L. Barton"'
Autor:
Peter R. Dodd, G.A.R. Johnston, John Hardy, Amanda J. L. Barton, S. C. Cheetham, Elisabeth Lofdahl
Publikováno v:
Journal of Neurochemistry. 47:460-467
Synaptosomes prepared from frozen postmortem human brain accumulated the neurotransmitter gamma-aminobutyric acid (GABA) and the conformationally restricted GABA analogue cis-3-aminocyclohexanecarboxylic acid (ACHC) by a sodium-dependent, temperature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371392c9d817f33d44e4a34abf3687a4
https://doi.org/10.1111/j.1471-4159.1986.tb04523.x
https://doi.org/10.1111/j.1471-4159.1986.tb04523.x
Autor:
Paul R. Murdock, Graham D Smith, Isro S Gloger, John Terrett, Kathryn Ellington, D.Malcolm Duckworth, Andrew D. Medhurst, Amanda J. L. Barton, Mark H Harries, Christopher D. Benham, Martin J. Gunthorpe, Andrew D. Randall, Helen J. Meadows, Simon Topp, David C. Harrison, Rab K. Prinjha, William Cairns, Catherine E. Clarke, Gareth J. Sanger, Owen Jenkins, John B. Davis, Philip David Hayes
Publikováno v:
Pain. 88:205-215
Capsaicin, resiniferatoxin, protons or heat have been shown to activate an ion channel, termed the rat vanilloid receptor-1 (rVR1), originally isolated by expression cloning for a capsaicin sensitive phenotype. Here we describe the cloning of a human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a232f7dc9ef6d689e3c5c246cf140a
https://doi.org/10.1016/s0304-3959(00)00353-5
https://doi.org/10.1016/s0304-3959(00)00353-5
Autor:
Mike Hutton, Vivienne F. Murphy, G.W. Roberts, Karen Duff, Matilde Caivano, John B. Davis, John Hardy, Amanda J. L. Barton, Laura G. Bresciani, Eric Karran, Carol W. Gray, Robin V. Ward
Publikováno v:
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. 5(4)
Presenilin-1 (PS-1) has been identified as the protein encoded by the chromosome 14 locus that, when mutated, leads to familial Alzheimer's disease (FAD). Using PS-1 transfected SHSY5Y neuroblastoma cells, we have demonstrated by immunodetection, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8064ef667ae820d4eb82dcca6bff846a
https://pubmed.ncbi.nlm.nih.gov/9117540
https://pubmed.ncbi.nlm.nih.gov/9117540
Autor:
Robert Clark, B Crook, Eric Karran, R.C.A. Pearson, John Hardy, D. M. A. Mann, George Roberts, Alison Goate, Deborah Dewar, Mike Hutton, Amanda J. L. Barton, Felix H Brown, David I. Graham, Karen Duff
Publikováno v:
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. 5(3)
The expression of the presenilin 1 (PS-1) gene has been investigated by in situ hybridization in early onset familial Alzheimer's disease (FAD), late onset Alzheimer's disease (AD) and normal control brain. Mutations in this gene are responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5829fe25abe10005d7bfa1e42281df7a
https://pubmed.ncbi.nlm.nih.gov/8910899
https://pubmed.ncbi.nlm.nih.gov/8910899
Autor:
Per Wester, Richard F. Cowburn, Anne-Marie O'Carroll, Elisabeth Lofdahl, John Hardy, Bengt Winblad, Amanda J. L. Barton, Peter R. Dodd, Gavin P. Reynolds
Publikováno v:
Neuroscience Letters. 73:192-196
Synaptosomal gamma-aminobutyric acid (GABA) uptake has been used as a biochemical marker for GABAergic terminals in controls and Alzheimer disease brains. Use of this marker suggests a large (ca. 70%) loss of cortical and hippocampal GABA terminals i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc8f9effd399d6050147f4b0335632c
https://doi.org/10.1016/0304-3940(87)90016-4
https://doi.org/10.1016/0304-3940(87)90016-4
Autor:
Anne-Marie O'Carroll, Per Wester, Richard F. Cowburn, Amanda J. L. Barton, Gavin P. Reynolds, Elisabeth Lofdahl, John Hardy, Bengt Winblad
Publikováno v:
Scopus-Elsevier
Synaptosomal D-aspartate has been used as a marker for glutamate neurons in control and in postmortem Alzheimer's disease brains. This technique shows a marked (60%) decrease of the glutamate uptake site in cortical and hippocampal regions. There wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c2bf5d9574b13a1afa802253f77194
https://pubmed.ncbi.nlm.nih.gov/2882446
https://pubmed.ncbi.nlm.nih.gov/2882446
Autor:
John Hardy, Amanda J. L. Barton
Publikováno v:
Biochemical Society Transactions. 15:558-559
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45c01d58839119f3c6ac121430010c77
https://doi.org/10.1042/bst0150558
https://doi.org/10.1042/bst0150558
Publikováno v:
Biochemical Society Transactions. 15:505-506
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1d2660835756e2b87f3782d994691a8
https://doi.org/10.1042/bst0150505
https://doi.org/10.1042/bst0150505