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pro vyhledávání: '"Amanda J. H. Gilliam"'
Autor:
Dmitry A. Fishman, Gregory A. Weiss, Kevin M. Johnston, Amanda J. H. Gilliam, Joshua N. Smith, Mark Balk, Sudipta Majumdar, Joshua M. Edgar, Andrew M. Gansmiller, Dylan Flather
Publikováno v:
Gilliam, AJH; Smith, JN; Flather, D; Johnston, KM; Gansmiller, AM; Fishman, DA; et al.(2016). Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization. JOURNAL OF MEDICINAL CHEMISTRY, 59(8), 4019-4025. doi: 10.1021/acs.jmedchem.5b01536. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/84m9p0sc
Journal of medicinal chemistry, vol 59, iss 8
Journal of medicinal chemistry, vol 59, iss 8
Caveolin-1 is a target for academic and pharmaceutical research due to its many cellular roles and associated diseases. We report peptide WL47 (1), a small, high-affinity, selective disrupter of caveolin-1 oligomers. Developed and optimized through s