Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Amanda J, Bird"'
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007262 (2018)
Zinc is an essential trace element that is required for the function of a large number of proteins. As these zinc-binding proteins are found within the cytosol and organelles, all eukaryotes require mechanisms to ensure that zinc is delivered to orga
Externí odkaz:
https://doaj.org/article/c148a3582c6d4ec1af3cc57baaee115c
Autor:
Stevin Wilson, Amanda J. Bird
Publikováno v:
Curr Opin Chem Biol
It is estimated that up to 10% of proteins in eukaryotes require zinc for their function. Although the majority of these proteins are located in the nucleus and cytosol, a small subset is secreted from cells or is located within an intracellular comp
Autor:
Mark P. Foster, Stevin Wilson, Vibhuti Wadhwa, Amanda J. Bird, Yi-Hsuan Liu, Carlos Cardona-Soto
Publikováno v:
Mol Microbiol
In Schizosaccharomyces pombe, the expression of the zrt1 zinc uptake gene is tightly regulated by zinc status. When intracellular zinc levels are low, zrt1 is highly expressed. However, when zinc levels are high, transcription of zrt1 is blocked in a
Publikováno v:
Journal of Biological Chemistry. 294:12392-12404
Genome-wide analyses have revealed that during metal ion starvation, many cells undergo programmed changes in their transcriptome or proteome that lower the levels of abundant metalloproteins, conserving metal ions for more critical functions. Here w
Publikováno v:
Molecular nutritionfood research. 65(7)
Chlorophyll is the vivid chromophore which imparts the green color to plant leaves, and is consumed by humans through green vegetables. The basic porphyrin structure of chlorophyll binds magnesium in plants, but can bind different divalent metals (e.
Publikováno v:
Curr Dev Nutr
OBJECTIVES: Developing countries rely on poorly bioavailable plant-based sources of iron (i.e., FeSO(4)), leading to iron deficiency anemia. Heme iron is more bioavailable, but predominantly found in red meat. Iron chlorophyllin (IC) utilizes the por
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e447d512cad8e2ebf6ede18ec03edcb
https://europepmc.org/articles/PMC7259199/
https://europepmc.org/articles/PMC7259199/
Autor:
Avery G Frey, Amanda J Bird, Marguerite V Evans-Galea, Elizabeth Blankman, Dennis R Winge, David J Eide
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22535 (2011)
The Zap1 transcription factor of Saccharomyces cerevisiae plays a central role in zinc homeostasis by controlling the expression of genes involved in zinc metabolism. Zap1 is active in zinc-limited cells and repressed in replete cells. At the transcr
Externí odkaz:
https://doaj.org/article/378ee71af2bc401ebad0b514b564c4fa
Autor:
Amanda J. Bird, Simon Labbé
Publikováno v:
Molecular Microbiology. 106:673-677
The zinc-responsive transcription activator Zap1 plays a central role in zinc homeostasis in the budding yeast Saccharomyces cerevisiae. In zinc-deficient cells, Zap1 binds to zinc responsive elements in target gene promoters and activates gene expre
Publikováno v:
Journal of Biological Chemistry. 292:13823-13832
Glycolysis and the pentose phosphate pathway both play a central role in the degradation of glucose in all domains of life. Another metabolic route that can facilitate glucose breakdown is the gluconate shunt. In this shunt glucose dehydrogenase and
Autor:
Amanda J. Bird, Stevin Wilson
Publikováno v:
Archives of Biochemistry and Biophysics. 611:30-36
The Zap1 transcription factor of Saccharomyces cerevisiae and the Loz1 transcription factor of Schizosaccharomyces pombe both play a central role in zinc homeostasis by controlling the expression of genes necessary for zinc metabolism. Zap1 activates