Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amanda Hamze"'
Autor:
Kimberly Stegmaier, Stuart H. Orkin, Nathanael S. Gray, Behnam Nabet, Yana Pikman, Lina Benajiba, Mark Wunderlich, Jennifer A. Perry, Delan Khalid, Amy Saur Conway, Amanda L. Robichaud, Neekesh V. Dharia, Linda S. Ross, Maxim Pimkin, Philipp J. Rauch, Hannah J. Uckelmann, Shan Lin, Amanda Hamze, Gabriela Alexe, Jana M. Ellegast
Leukemic blasts are immune cells gone awry. We hypothesized that dysregulation of inflammatory pathways contributes to the maintenance of their leukemic state and can be exploited as cell-intrinsic, self-directed immunotherapy. To this end, we applie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba948aac00d83e6eb1459f42fd9c93e6
https://doi.org/10.1158/2159-8290.c.6549664
https://doi.org/10.1158/2159-8290.c.6549664
Autor:
Kimberly Stegmaier, Stuart H. Orkin, Nathanael S. Gray, Behnam Nabet, Yana Pikman, Lina Benajiba, Mark Wunderlich, Jennifer A. Perry, Delan Khalid, Amy Saur Conway, Amanda L. Robichaud, Neekesh V. Dharia, Linda S. Ross, Maxim Pimkin, Philipp J. Rauch, Hannah J. Uckelmann, Shan Lin, Amanda Hamze, Gabriela Alexe, Jana M. Ellegast
Supplementary Table from Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618ca88f8ca45259be8f65cbb954e290
https://doi.org/10.1158/2159-8290.22541509
https://doi.org/10.1158/2159-8290.22541509
Autor:
Jana M. Ellegast, Gabriela Alexe, Amanda Hamze, Shan Lin, Hannah J. Uckelmann, Philipp J. Rauch, Maxim Pimkin, Linda S. Ross, Neekesh V. Dharia, Amanda L. Robichaud, Amy Saur Conway, Delan Khalid, Jennifer A. Perry, Mark Wunderlich, Lina Benajiba, Yana Pikman, Behnam Nabet, Nathanael S. Gray, Stuart H. Orkin, Kimberly Stegmaier
Publikováno v:
Cancer discovery. 12(7)
Leukemic blasts are immune cells gone awry. We hypothesized that dysregulation of inflammatory pathways contributes to the maintenance of their leukemic state and can be exploited as cell-intrinsic, self-directed immunotherapy. To this end, we applie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7711f13fafbbaf23d540489744c6acc
https://pubmed.ncbi.nlm.nih.gov/35791696
https://pubmed.ncbi.nlm.nih.gov/35791696
Autor:
Jana M. Ellegast, Gabriela Alexe, Amanda Hamze, Shan Lin, Hannah J. Uckelmann, Philipp J. Rauch, Maxim Pimkin, Linda Ross, Neekesh V. Dharia, Amanda L. Robichaud, Amy Conway Saur, Delan Khalid, Mark Wunderlich, Lina Benajiba, Behnam Nabet, Nathanael S. Gray, Stuart H. Orkin, Kimberly Stegmaier
Publikováno v:
Cancer Research. 82:LB076-LB076
Leukemic blasts are immune cells gone awry. We thus hypothesized that dysregulation of inflammatory pathways can maintain a leukemic state. In contrast to traditional cancer immunotherapy, we exploited inflammatory signaling within AML blasts as cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b8900373938e3e2cee9e71f5d4a2315
https://doi.org/10.1158/1538-7445.am2022-lb076
https://doi.org/10.1158/1538-7445.am2022-lb076
Autor:
Neekesh V. Dharia, Katherine A. Donovan, Amanda Hamze, Nathanael S. Gray, Amy Saur Conway, Björn Stolte, Kimberly Stegmaier, Shan Lin, Federica Piccioni, Xavier Darzacq, Biniam Adane, Amanda L. Robichaud, Jialin Sun, Bo Kyung A. Seong, Eric S. Fischer, Behnam Nabet, Emily Jue Wang, Shasha Chong, Gabriela Alexe, Linda Ross, Fleur M. Ferguson
Publikováno v:
Cancer Cell
Summary Fusion-transcription factors (fusion-TFs) represent a class of driver oncoproteins that are difficult to therapeutically target. Recently, protein degradation has emerged as a strategy to target these challenging oncoproteins. The mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7f719200606a8617d43dfb33b0c110
https://pubmed.ncbi.nlm.nih.gov/34329586
https://pubmed.ncbi.nlm.nih.gov/34329586
Autor:
Mark Wunderlich, Behnam Nabet, Linda Ross, Kimberly Stegmaier, Amanda L Robinchaud, Amy Saur Conway, Delan Khalid, Neekesh V. Dharia, Lina Benajiba, Stuart H. Orkin, Shan Lin, Jana M. Ellegast, Amanda Hamze, Nathanael S. Gray, Gabriela Alexe, Maxim Pimkin
Publikováno v:
Blood. 138:3305-3305
Leukemic blasts are immune cells gone awry. We hypothesized that dysregulation of inflammatory pathways contributes to the maintenance of their leukemic state and can be exploited as cell-intrinsic, self-directed immunotherapy. To test the hypothesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::353164a4476e3160aa0b09d573065dba
https://doi.org/10.1182/blood-2021-151511
https://doi.org/10.1182/blood-2021-151511