Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Amanda H Kahn-Kirby"'
Autor:
Amanda H Kahn-Kirby, Akiko Amagata, Celine I Maeder, Janet J Mei, Steve Sideris, Yuko Kosaka, Andrew Hinman, Stephanie A Malone, Joel J Bruegger, Leslie Wang, Virna Kim, William D Shrader, Kevin G Hoff, Joey C Latham, Euan A Ashley, Matthew T Wheeler, Enrico Bertini, Rosalba Carrozzo, Diego Martinelli, Carlo Dionisi-Vici, Kimberly A Chapman, Gregory M Enns, William Gahl, Lynne Wolfe, Russell P Saneto, Simon C Johnson, Jeffrey K Trimmer, Matthew B Klein, Charles R Holst
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214250 (2019)
BACKGROUND:Mitochondrial disease is a family of genetic disorders characterized by defects in the generation and regulation of energy. Epilepsy is a common symptom of mitochondrial disease, and in the vast majority of cases, refractory to commonly us
Externí odkaz:
https://doaj.org/article/8d6a4743a7c54e47b90913a261c70803
Autor:
Andrew Hinman, Charles R Holst, Joey C Latham, Joel J Bruegger, Gözde Ulas, Kevin P McCusker, Akiko Amagata, Dana Davis, Kevin G Hoff, Amanda H Kahn-Kirby, Virna Kim, Yuko Kosaka, Edgar Lee, Stephanie A Malone, Janet J Mei, Steve James Richards, Veronica Rivera, Guy Miller, Jeffrey K Trimmer, William D Shrader
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201369 (2018)
Ferroptosis is a form of programmed cell death associated with inflammation, neurodegeneration, and ischemia. Vitamin E (alpha-tocopherol) has been reported to prevent ferroptosis, but the mechanism by which this occurs is controversial. To elucidate
Externí odkaz:
https://doaj.org/article/1875891c4736481eb71993aa2c674781
Autor:
Seth I. Berger, Georgia Pitsava, Andrea J. Cohen, Emmanuèle C. Délot, Jonathan LoTempio, Erin Hallie Andrew, Gloria Mas Martin, Sofia Marmolejos, Jessica Albert, Beatrix Meltzer, Jamie Fraser, Debra S. Regier, Amanda H. Kahn‐Kirby, Erica Smith, Susan Knoblach, Arthur Ko, Vincent A. Fusaro, Eric Vilain
Publikováno v:
Clinical Genetics.
Autor:
Edgar Lee, Akiko Amagata, Yuko Kosaka, William D. Shrader, Jeffrey K. Trimmer, Joey C. Latham, Stephanie Malone, Joel J. Bruegger, Andrew W. Hinman, Janet J. Mei, Guy M. Miller, Kevin P. McCusker, Veronica Rivera, Gözde Ulas, Charles R. Holst, Steve James Richards, Dana A. Davis, Amanda H. Kahn-Kirby, Kevin G. Hoff, Virna Kim
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201369 (2018)
PLoS ONE
PLoS ONE
Ferroptosis is a form of programmed cell death associated with inflammation, neurodegeneration, and ischemia. Vitamin E (alpha-tocopherol) has been reported to prevent ferroptosis, but the mechanism by which this occurs is controversial. To elucidate
Autor:
Steven J. Husson, Liliane Schoofs, Kaveh Ashrafi, Geert Baggerman, Amanda H. Kahn-Kirby, Brigitte A Bogert, Tom Janssen
Publikováno v:
Journal of Neurochemistry. 102:246-260
Biologically active peptides are synthesized from inactive pre-proproteins or peptide precursors by the sequential actions of processing enzymes. Proprotein convertases cleave the precursor at pairs of basic amino acids, which are then removed from t
Publikováno v:
Annual Review of Physiology. 68:719-736
▪ Abstract The TRP (transient receptor potential) superfamily of cation channels is present in all eukaryotes, from yeast to mammals. Many TRP channels have been studied in the nematode Caenorhabditis elegans, revealing novel biological functions,
Autor:
John Browse, Amanda H. Kahn-Kirby, Jennifer L. Watts, Alfonso junior Apicella, Cornelia I. Bargmann, Jami L.M. Dantzker, William R Schafer
Publikováno v:
Cell. 119(6)
A variety of lipid and lipid-derived molecules can modulate TRP cation channel activity, but the identity of the lipids that affect TRP channel function in vivo is unknown. Here, we use genetic and behavioral analysis in the nematode C. elegans to im