Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Amanda Gatesman Ammer"'
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13847 (2010)
Tumor cell motility and invasion is governed by dynamic regulation of the cortical actin cytoskeleton. The actin-binding protein cortactin is commonly upregulated in multiple cancer types and is associated with increased cell migration. Cortactin reg
Externí odkaz:
https://doaj.org/article/5ae17c1d7b5343819490f18fd8aebf7d
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Analysis of the biomedical workforce and graduate education have produced recommendations for modifications of pre-doctoral training to broadly prepare trainees for wider ranging scientific careers. Development of training in prof
Externí odkaz:
https://doaj.org/article/5f6610bf3a53402ab3f435d508674975
Autor:
Ethan Meadows, Debbie Piktel, John M. Hollander, Karen H. Martin, Javohn C. Moore, Mark V. Pinti, Laura F. Gibson, Stephanie L. Rellick, Amanda Gatesman Ammer, Werner J. Geldenhuys
Publikováno v:
Free Radic Biol Med
B-cell acute lymphoblastic leukemia (ALL) affects both pediatric and adult patients. Chemotherapy resistant tumor cells that contribute to minimal residual disease (MRD) underlie relapse and poor clinical outcomes in a sub-set of patients. Targeting
Autor:
Courtney D. Amend, Edwin C. K. Wan, Heng Hu, James E. Coad, Xuefang Ren, Breanne Y. Farris, Wen Zheng, Kelly L. Monaghan, Amanda Gatesman Ammer
Publikováno v:
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 326-341 (2019)
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 326-341 (2019)
Introduction Stroke‐associated pneumonia (SAP) is a major cause of mortality in patients who have suffered from severe ischemic stroke. Although multifactorial in nature, stroke‐induced immunosuppression plays a key role in the development of SAP
Autor:
Kathleen M. Brundage, Mackenzie Newman, Quincy A. Hathaway, Peter H. Mathers, David P. Siderovski, B. J. P. Gall, Amanda Gatesman Ammer, Robert Hull, Han-Gang Yu
Publikováno v:
Journal of Arrhythmia
Journal of Arrhythmia, Vol 37, Iss 5, Pp 1337-1347 (2021)
Journal of Arrhythmia, Vol 37, Iss 5, Pp 1337-1347 (2021)
Background Missense mutations in the hyperpolarization‐activated cyclic nucleotide‐modulated (HCN) channel 4 (HCN4) are one of the genetic causes of cardiac sinus bradycardia. Objective To investigate possible HCN4 channel mutation in a young pat
Autor:
Amanda Gatesman Ammer, Kathleen M. Brundage, James E. Coad, Elena N. Pugacheva, Malcolm D. Mattes, Karen H. Martin, Mackenzie Newman, Gina Sizemore, Sarah L. McLaughlin, Han-Gang Yu
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Background Unlike other breast cancer subtypes that may be treated with a variety of hormonal or targeted therapies, there is a need to identify new, effective targets for triple-negative breast cancer (TNBC). It has recently been recognized that mem
Autor:
Ryan Percifield, Nik Kovinich, Aniello M. Infante, Amanda Gatesman Ammer, Brianna Harris, Matthew Lowery, Katie Coburn, Asraful Jahan
Publikováno v:
BMC Genomics
BMC Genomics, Vol 20, Iss 1, Pp 1-21 (2019)
BMC Genomics, Vol 20, Iss 1, Pp 1-21 (2019)
Background Glyceollins are isoflavonoid-derived pathogen-inducible defense metabolites (phytoalexins) from soybean (Glycine max L. Merr) that have important roles in providing defense against pathogens. They also have impressive anticancer and neurop
Autor:
Jessica L. Allen, Erik T. Interval, Scott A. Weed, Brenen W. Papenberg, River A. Hames, Dorothy A. Schafer, Johnathan E. Castaño, Amanda Gatesman Ammer, Steven M. Markwell
Publikováno v:
Molecular cancer research : MCR. 17(4)
Malregulation of the actin cytoskeleton enhances tumor cell motility and invasion. The actin-binding protein cortactin facilitates branched actin network formation through activation of the actin-related protein (Arp) 2/3 complex. Increased cortactin
Autor:
Han-Gang Yu, Mackenzie Newman, James E. Coad, Karen H. Martin, Kathleen M. Brundage, Amanda Gatesman Ammer, Sarah L. McLaughlin
Publikováno v:
BMC Cancer
Background Human triple-negative breast cancer has limited therapeutic choices. Breast tumor cells have depolarized plasma membrane potential. Using this unique electrical property, we aim to develop an effective selective killing of triple-negative
Autor:
Yon Rojansakul, Amruta Manke, Amanda Gatesman Ammer, Vincent Castranova, Liying Wang, Yong Yang, Karen H. Martin, Sudjit Luanpitpong
Publikováno v:
Nano Letters
We developed a three-dimensional fibroblastic nodule model for fibrogenicity testing of nanomaterials and investigated the role of fibroblast stemlike cells (FSCs) in the fibrogenic process. We showed that carbon nanotubes (CNTs) induced fibroblastic