Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Amanda Gatesman Ammer"'
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Analysis of the biomedical workforce and graduate education have produced recommendations for modifications of pre-doctoral training to broadly prepare trainees for wider ranging scientific careers. Development of training in prof
Externí odkaz:
https://doaj.org/article/5f6610bf3a53402ab3f435d508674975
Autor:
Courtney D. Amend, Edwin C. K. Wan, Heng Hu, James E. Coad, Xuefang Ren, Breanne Y. Farris, Wen Zheng, Kelly L. Monaghan, Amanda Gatesman Ammer
Publikováno v:
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 326-341 (2019)
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 326-341 (2019)
Introduction Stroke‐associated pneumonia (SAP) is a major cause of mortality in patients who have suffered from severe ischemic stroke. Although multifactorial in nature, stroke‐induced immunosuppression plays a key role in the development of SAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc5a25f220e6cf9dfa488025d82085f
https://doi.org/10.1002/iid3.277
https://doi.org/10.1002/iid3.277
Autor:
Kathleen M. Brundage, Mackenzie Newman, Quincy A. Hathaway, Peter H. Mathers, David P. Siderovski, B. J. P. Gall, Amanda Gatesman Ammer, Robert Hull, Han-Gang Yu
Publikováno v:
Journal of Arrhythmia
Journal of Arrhythmia, Vol 37, Iss 5, Pp 1337-1347 (2021)
Journal of Arrhythmia, Vol 37, Iss 5, Pp 1337-1347 (2021)
Background Missense mutations in the hyperpolarization‐activated cyclic nucleotide‐modulated (HCN) channel 4 (HCN4) are one of the genetic causes of cardiac sinus bradycardia. Objective To investigate possible HCN4 channel mutation in a young pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58eef8b0dae995c4afcf8e80a783cddd
https://pubmed.ncbi.nlm.nih.gov/34621433
https://pubmed.ncbi.nlm.nih.gov/34621433
Autor:
Amanda Gatesman Ammer, Kathleen M. Brundage, James E. Coad, Elena N. Pugacheva, Malcolm D. Mattes, Karen H. Martin, Mackenzie Newman, Gina Sizemore, Sarah L. McLaughlin, Han-Gang Yu
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Background Unlike other breast cancer subtypes that may be treated with a variety of hormonal or targeted therapies, there is a need to identify new, effective targets for triple-negative breast cancer (TNBC). It has recently been recognized that mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ba6f45c2859052362e2d2d650c7a7d
https://pubmed.ncbi.nlm.nih.gov/32586284
https://pubmed.ncbi.nlm.nih.gov/32586284
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13847 (2010)
Tumor cell motility and invasion is governed by dynamic regulation of the cortical actin cytoskeleton. The actin-binding protein cortactin is commonly upregulated in multiple cancer types and is associated with increased cell migration. Cortactin reg
Externí odkaz:
https://doaj.org/article/5ae17c1d7b5343819490f18fd8aebf7d
Autor:
Ryan Percifield, Nik Kovinich, Aniello M. Infante, Amanda Gatesman Ammer, Brianna Harris, Matthew Lowery, Katie Coburn, Asraful Jahan
Publikováno v:
BMC Genomics
BMC Genomics, Vol 20, Iss 1, Pp 1-21 (2019)
BMC Genomics, Vol 20, Iss 1, Pp 1-21 (2019)
Background Glyceollins are isoflavonoid-derived pathogen-inducible defense metabolites (phytoalexins) from soybean (Glycine max L. Merr) that have important roles in providing defense against pathogens. They also have impressive anticancer and neurop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5dfeb1efc8a16acba733248ab1b6620
https://pubmed.ncbi.nlm.nih.gov/30786857
https://pubmed.ncbi.nlm.nih.gov/30786857
Autor:
Jessica L. Allen, Erik T. Interval, Scott A. Weed, Brenen W. Papenberg, River A. Hames, Dorothy A. Schafer, Johnathan E. Castaño, Amanda Gatesman Ammer, Steven M. Markwell
Publikováno v:
Molecular cancer research : MCR. 17(4)
Malregulation of the actin cytoskeleton enhances tumor cell motility and invasion. The actin-binding protein cortactin facilitates branched actin network formation through activation of the actin-related protein (Arp) 2/3 complex. Increased cortactin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f90e568c8519780513238fb80f390d
https://pubmed.ncbi.nlm.nih.gov/30610108
https://pubmed.ncbi.nlm.nih.gov/30610108
Autor:
Han-Gang Yu, Mackenzie Newman, James E. Coad, Karen H. Martin, Kathleen M. Brundage, Amanda Gatesman Ammer, Sarah L. McLaughlin
Publikováno v:
BMC Cancer
Background Human triple-negative breast cancer has limited therapeutic choices. Breast tumor cells have depolarized plasma membrane potential. Using this unique electrical property, we aim to develop an effective selective killing of triple-negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f765f8f37b97be85e409bab821dc70
https://doi.org/10.1186/s12885-017-3168-x
https://doi.org/10.1186/s12885-017-3168-x
Autor:
Yon Rojansakul, Amruta Manke, Amanda Gatesman Ammer, Vincent Castranova, Liying Wang, Yong Yang, Karen H. Martin, Sudjit Luanpitpong
Publikováno v:
Nano Letters
We developed a three-dimensional fibroblastic nodule model for fibrogenicity testing of nanomaterials and investigated the role of fibroblast stemlike cells (FSCs) in the fibrogenic process. We showed that carbon nanotubes (CNTs) induced fibroblastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e5becb24a4b90ce914becd0fa15cc4
https://doi.org/10.1021/nl5002026
https://doi.org/10.1021/nl5002026
Autor:
Karen H. Martin, John E. Jett, Jason C. Breaux, Chris A. Bolcato, Amanda Gatesman Ammer, Peter M. Gannett, Jason V. Evans, Mark Culp, Scott A. Weed
Publikováno v:
Journal of Cell Science. 125:6185-6197
Summary Tyrosine-kinase-based signal transduction mediated by modular protein domains is critical for cellular function. The Src homology (SH)2 domain is an important conductor of intracellular signaling that binds to phosphorylated tyrosines on acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18200954084ff6d6ab164563183c6982
https://doi.org/10.1242/jcs.121046
https://doi.org/10.1242/jcs.121046