Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amanda Garfield"'
Autor:
Alexis Diaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine XY Khor, Nigel Turner, Xin Y Lim, Miro A Astore, Jonathan C Morris, Anthony S Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew P Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Publikováno v:
eLife, Vol 12 (2023)
Insulin resistance (IR) is a complex metabolic disorder that underlies several human diseases, including type 2 diabetes and cardiovascular disease. Despite extensive research, the precise mechanisms underlying IR development remain poorly understood
Externí odkaz:
https://doaj.org/article/d4808a63f21b4fbe996fd89139b71d2a
Autor:
Simona Zarini, Joseph T. Brozinick, Karin A. Zemski Berry, Amanda Garfield, Leigh Perreault, Anna Kerege, Hai Hoang Bui, Phil Sanders, Parker Siddall, Ming Shang Kuo, Bryan C. Bergman
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 10, Pp 100270- (2022)
Serum ceramides, especially C16:0 and C18:0 species, are linked to CVD risk and insulin resistance, but details of this association are not well understood. We performed this study to quantify a broad range of serum sphingolipids in individuals spann
Externí odkaz:
https://doaj.org/article/7d7ffd7ab7914895aaddc87b15411a05
Autor:
Darcy Kahn, Emily Macias, Simona Zarini, Amanda Garfield, Karin Zemski Berry, Robert Gerszten, Jonathan Schoen, Melanie Cree‐Green, Bryan C. Bergman
Publikováno v:
Physiological Reports, Vol 10, Iss 16, Pp n/a-n/a (2022)
Abstract Adipose tissue secretes an abundance of lipid and protein mediators, and this secretome is depot‐specific, with local and systemic effects on metabolic regulation. Intermuscular adipose tissue (IMAT) accumulates within the skeletal muscle
Externí odkaz:
https://doaj.org/article/89282c4a12b145a2b6743455e1dbda1e
Autor:
Stephan G. Bodkin, Andrew C. Smith, Bryan C. Bergman, Donglai Huo, Kenneth A. Weber, Simona Zarini, Darcy Kahn, Amanda Garfield, Emily Macias, Michael O. Harris-Love
Publikováno v:
Frontiers in Rehabilitation Sciences, Vol 3 (2022)
PurposeTo train and test a machine learning model to automatically measure mid-thigh muscle cross-sectional area (CSA) to provide rapid estimation of appendicular lean mass (ALM) and predict knee extensor torque of obese adults.MethodsObese adults [b
Externí odkaz:
https://doaj.org/article/f7f91e54f7c9470cb5c4fe2f0fbfeff3
Autor:
Darcy Kahn, Simona Zarini, Emily Macias, Amanda Garfield, Kathleen Harrison, Melanie Cree-Green, Jonathan Schoen, Bryan Bergman
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 9-9 (2020)
OBJECTIVES/GOALS: Intermuscular adipose tissue (IMAT) has been associated with insulin resistance and type 2 diabetes, yet mechanistic studies addressing the functional role of IMAT are lacking. The aim of this work was to identify novel mechanisms b
Externí odkaz:
https://doaj.org/article/99b313d2b3a848f08881b9fefa584466
Autor:
Bryan C. Bergman, Anna Kerege, Leigh Perreault, Amanda Garfield, Darcy E. Kahn, Karin A. Zemski Berry, Simona Zarini
Sphingolipids are thought to promote skeletal muscle insulin resistance. 1-Deoxysphingolipids (dSL) are atypical sphingolipids that are increased in plasma of individuals with type 2 diabetes and cause β-cell dysfunction in vitro. However, their rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31491282c7bd98b77cab00fd0a058243
https://doi.org/10.2337/figshare.22666174.v1
https://doi.org/10.2337/figshare.22666174.v1
Autor:
Darcy Kahn, Emily Macias, Simona Zarini, Amanda Garfield, Karin Zemski Berry, Paul MacLean, Robert E Gerszten, Andrew Libby, Claudia Solt, Jonathan Schoen, Bryan C Bergman
Publikováno v:
Endocrinology
Adipose tissue secretions are depot-specific and vary based on anatomical location. Considerable attention has been focused on visceral (VAT) and subcutaneous (SAT) adipose tissue with regard to metabolic disease, yet our knowledge of the secretome f
Autor:
Erin Finn, Meredith A Ware, Haseeb Rahat, Yesenia Garcia Reyes, Anya Taylor, Amanda Garfield, Bryan C Bergman, Kristen Nadeau, Melanie Cree-Green
Publikováno v:
Journal of the Endocrine Society. 6:A667-A667
Background Polycystic ovary syndrome (PCOS) is common and associated with metabolic disease, in particular glucose abnormalities and insulin resistance (IR). Fat metabolism is linked with IR, manifesting as decreased suppression of lipolysis followin
Autor:
Emily Macias, Bryan C. Bergman, Darcy E. Kahn, Simona Zarini, Amanda Garfield, Jonathan A. Schoen, Kathleen A. Harrison, Melanie Cree-Green
Publikováno v:
Journal of Clinical and Translational Science. 4:9-9
OBJECTIVES/GOALS: Intermuscular adipose tissue (IMAT) has been associated with insulin resistance and type 2 diabetes, yet mechanistic studies addressing the functional role of IMAT are lacking. The aim of this work was to identify novel mechanisms b