Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Amanda G. Fallowfield"'
Autor:
Gillian A. Bottomley, Elizabeth A. Conway, Irene Cowan, Michael Richard Attwood, Elizabeth Keech, Neera Borkakoti, Stephen J. Kirtland, Francis Xavier Wilson, P. Jones, Balraj Krishnan Handa, Amanda G. Fallowfield, Glyn Williams
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1869-1874
Identification of the extracellular domains of the interleukin-8 (IL-8) receptor led to the synthesis of several peptide sequences. A peptide derived from a single subdomain was shown to inhibit IL-8 binding and to act as a functional antagonist. Ala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a81c310d083bb9119199a03551d8878
https://doi.org/10.1016/0960-894x(96)00331-9
https://doi.org/10.1016/0960-894x(96)00331-9
Autor:
Stephen J. Kirtland, Amanda G. Fallowfield, Neera Borkakoti, Lauri Price, Jones Philip Stephen, Gillian A. Bottomley, Glyn J. Price, Glyn Williams, Irene Cowan
Publikováno v:
Journal of Biological Chemistry. 271:9579-9586
Interleukin-8 (IL-8) is a dimeric, C-X-C chemokine, produced by a variety of cells and which elicits pro-inflammatory responses from the neutrophil. As a prelude to drug design, we have investigated the interactions between IL-8 and its receptor by p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f14b98822aba811e9a8b05857d55cc
https://doi.org/10.1074/jbc.271.16.9579
https://doi.org/10.1074/jbc.271.16.9579