Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amanda G. Allen"'
Autor:
Christina Gross, Nisha Raj, Gemma Molinaro, Amanda G. Allen, Alonzo J. Whyte, Jay R. Gibson, Kimberly M. Huber, Shannon L. Gourley, Gary J. Bassell
Publikováno v:
Cell Reports, Vol 11, Iss 5, Pp 681-688 (2015)
Distinct isoforms of the PI3K catalytic subunit have specialized functions in the brain, but their role in cognition is unknown. Here, we show that the catalytic subunit p110β plays an important role in prefrontal cortex (PFC)-dependent cognitive de
Externí odkaz:
https://doaj.org/article/ae503f1f74b54f07ba444d74a3b4f8e2
Autor:
Amanda G. Allen, Stephen C. Anderson
Publikováno v:
Journal of Education & Social Policy. 7
Autor:
Christina Gross, Deepak Tiwari, Gary J. Bassell, Anwesha Banerjee, Eric Klann, Lindsay M. Schroeder-Carter, Amanda G. Allen, Nada A. Elsayed, Rosemary Puckett, Joseph C. Krzeski, Shannon L. Gourley, Francesco Longo, Angela R. White, Ralph A. Rivero
Publikováno v:
Neuropsychopharmacology. 44:324-333
Defects in the phosphoinositide 3-kinase (PI3K) pathway are shared characteristics in several brain disorders, including the inherited intellectual disability and autism spectrum disorder, fragile X syndrome (FXS). PI3K signaling therefore could serv
An essential component of goal-directed decision-making is the ability to maintain flexible responding based on the value of a given reward, or “reinforcer.” The medial orbitofrontal cortex (mOFC), a subregion of the ventromedial prefrontal corte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfa31e43fc24c25fb5688e6176baa98
https://europepmc.org/articles/PMC4837686/
https://europepmc.org/articles/PMC4837686/
Autor:
Lauren P. Shapiro, Shannon L. Gourley, Lauren M. DePoy, Laura M. Butkovich, Andrew M. Swanson, Amanda G. Allen
The GABAA receptor mediates fast, inhibitory signaling, and cortical expression of the α1 subunit increases during postnatal development. Certain pathological stimuli such as stressors or prenatal cocaine exposure can interfere with this process, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8832c565335fbce0febc6dc31db0cfeb
https://europepmc.org/articles/PMC4826739/
https://europepmc.org/articles/PMC4826739/
GABAAα1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 40(4)
An essential aspect of goal-directed action selection is differentiating between behaviors that are more, or less, likely to be reinforced. Habits, by contrast, are stimulus-elicited behaviors insensitive to action–outcome contingencies and are con
Prefrontal cortical dendritic spine remodeling during adolescence may open a window of vulnerability to pathological stimuli that impact long-term behavioral outcomes, but causal mechanisms remain unclear. We administered the Rho-kinase inhibitor HA-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7b4386e364e45392bc778121419106
https://europepmc.org/articles/PMC3619219/
https://europepmc.org/articles/PMC3619219/
Publikováno v:
Translational Psychiatry
Adolescent cocaine use increases the likelihood of drug abuse and addiction in adulthood, and etiological factors may include a cocaine-induced bias towards so-called ‘reward-seeking’ habits. To determine whether adolescent cocaine exposure indee