Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Amanda Freire-Assis"'
Autor:
Pedro Paranhos Tanaka, Ernna Hérida Oliveira, Mayara Cristina Vieira-Machado, Max Jordan Duarte, Amanda Freire Assis, Karina Fittipaldi Bombonato-Prado, Geraldo Aleixo Passos
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background The autoimmune regulator (Aire) gene is critical for the appropriate establishment of central immune tolerance. As one of the main controllers of promiscuous gene expression in the thymus, Aire promotes the expression of thousands
Externí odkaz:
https://doaj.org/article/66167b34244b439d83ab62680486689f
Autor:
Ana Carolina Monteleone-Cassiano, Janaina A. Dernowsek, Romario S. Mascarenhas, Amanda Freire Assis, Dimitrius Pitol, Natalia Chermont Santos Moreira, Elza Tiemi Sakamoto-Hojo, João Paulo Mardegan Issa, Eduardo A. Donadi, Geraldo Aleixo Passos
Publikováno v:
BMC Molecular and Cell Biology, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Besides controlling the expression of peripheral tissue antigens, the autoimmune regulator (AIRE) gene also regulates the expression of adhesion genes in medullary thymic epithelial cells (mTECs), an essential process for mTEC-thy
Externí odkaz:
https://doaj.org/article/21f76be474554b46a02bf58f15e78132
Autor:
Maidy Rehder Wimmers Ferreira, Roger Rodrigo Fernandes, Amanda Freire Assis, Janaína A. Dernowsek, Geraldo A. Passos, Fabio Variola, Karina Fittipaldi Bombonato-Prado
Publikováno v:
International Journal of Biomaterials, Vol 2016 (2016)
Titanium implants have been extensively used in orthopedic and dental applications. It is well known that micro- and nanoscale surface features of biomaterials affect cellular events that control implant-host tissue interactions. To improve our under
Externí odkaz:
https://doaj.org/article/91136e62c4824a819a4e7b1715dac85f
Autor:
Paula B. Donate, Catherine P. Nguyen, Amanda Freire Assis, Geraldo Aleixo Silva Passos, Ernna Hérida Domingues de Oliveira, Silvana Giuliatti
Publikováno v:
Transcriptomics in Health and Disease ISBN: 9783030878207
Transcriptomics in Health and Disease ISBN: 9783319119847
Transcriptomics in Health and Disease ISBN: 9783319119847
The concept of the transcriptome revolves around the complete set of transcripts present in a given cell type, tissue or organ and encompasses both coding and non-coding RNA molecules, although we often assume that it consists only of messenger RNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c521f1d56b2c3ba70f48ecd4e0303404
https://doi.org/10.1007/978-3-030-87821-4_1
https://doi.org/10.1007/978-3-030-87821-4_1
Autor:
Janaina Dernowsek, Ana Carolina Monteleone-Cassiano, João Paulo Mardegan Issa, Romario S. Mascarenhas, Eduardo Antônio Donadi, Dimitrius Leonardo Pitol, Geraldo Aleixo Silva Passos, Amanda Freire Assis
Besides controlling the expression of peripheral tissue antigens, the autoimmune regulator (AIRE) gene also regulates the expression of adhesion genes in medullary thymic epithelial cells (mTECs), an essential process for mTEC-thymocyte interaction f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf72d23c450c510c381233df48020ee
https://doi.org/10.1101/2021.08.11.455994
https://doi.org/10.1101/2021.08.11.455994
Autor:
Romario S. Mascarenhas, Max Jordan Duarte, Geraldo Aleixo Silva Passos, Pedro Paranhos Tanaka, Cesar A. Speck-Hernandez, Amanda Freire Assis
The autoimmune regulator (Aire) gene in medullary thymic epithelial cells (mTECs) encodes the AIRE protein, which interacts with its partners within the nucleus. This “Aire complex” induces stalled RNA Pol II on chromatin to proceed with transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76dbb77e6f82c283de1e9763c30079d2
https://doi.org/10.1101/2021.07.14.452339
https://doi.org/10.1101/2021.07.14.452339
Autor:
Nicole Pezzi, Larissa Cotrim-Sousa, Amanda Freire-Assis, Ernna Hérida Domingues de Oliveira, Geraldo Aleixo Silva Passos, Pedro Paranhos Tanaka
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
In this work, we demonstrate that adhesion between medullary thymic epithelial cells (mTECs) and thymocytes is controlled by miRNAs. Adhesion between mTECs and developing thymocytes is essential for triggering negative selection (NS) of autoreactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aac5a70f62bfba980e7d6e91c32345b
https://doi.org/10.1016/j.molimm.2019.09.010
https://doi.org/10.1016/j.molimm.2019.09.010
Autor:
Amanda Freire Assis, Karina Fittipaldi Bombonato-Prado, Max Jordan Duarte, Pedro Paranhos Tanaka, Geraldo Aleixo Silva Passos, Ernna Hérida Domingues de Oliveira, Vieira-Machado Mc
Publikováno v:
BMC genomics. 23(1)
Background The autoimmune regulator (Aire) gene is critical for the appropriate establishment of central immune tolerance. As one of the main controllers of promiscuous gene expression in the thymus, Aire promotes the expression of thousands of downs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f76e261334b5514fba0f1e15d6fb15
https://pubmed.ncbi.nlm.nih.gov/35643451
https://pubmed.ncbi.nlm.nih.gov/35643451
Autor:
Amanda Freire Assis, Geraldo Aleixo Silva Passos, Cesar A. Speck-Hernandez, Daniella Arêas Mendes-da-Cruz
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Twenty years ago, the autoimmune regulator (Aire) gene was associated with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, and was cloned and sequenced. Its importance goes beyond its abstract link with human autoimmune disease. Aire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ababd65744b65c757d4a4f56e122d7bb
https://doi.org/10.1111/imm.12831
https://doi.org/10.1111/imm.12831
Autor:
Janaina Dernowsek, Selma Siéssere, Mayara Sgarbi Semeghini, Amanda Freire Assis, Karina Fittipaldi Bombonato-Prado, Adalberto Luiz Rosa, Geraldo Aleixo Silva Passos, Roger Rodrigo Fernandes, Fernanda Grilo de Azevedo
Publikováno v:
Cell Biology International. 42:12-24
Investigation on functional genome research may contribute to the knowledge of functional roles of different mRNAs and miRNAs in bone cells of osteoporotic animals. Currently, few studies indicate the changes in gene modulation that osteoporosis caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd24df4aeea5458a262dc3b167286178
https://doi.org/10.1002/cbin.10802
https://doi.org/10.1002/cbin.10802