Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Amanda Ferreira Vidal"'
Autor:
Amanda Ferreira Vidal, Rafaella Sousa Ferraz, Antonette El-Husny, Caio Santos Silva, Tatiana Vinasco-Sandoval, Leandro Magalhães, Milene Raiol-Moraes, Williams Fernandes Barra, Cynthia Lara Brito Lins Pereira, Paulo Pimentel de Assumpção, Leonardo Miranda de Brito, Ricardo Assunção Vialle, Sidney Santos, Ândrea Ribeiro-dos-Santos, André M. Ribeiro-dos-Santos
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Next generation sequencing (NGS) has been a handy tool in clinical practice, mainly due to its efficiency and cost-effectiveness. It has been widely used in genetic diagnosis of several inherited diseases, and, in clinical oncolog
Externí odkaz:
https://doaj.org/article/8f815626122642838232d85a9b8cb17a
Autor:
Giovanna Chaves Cavalcante, Anderson N. R. Marinho, Ana Karyssa Anaissi, Tatiana Vinasco-Sandoval, André Ribeiro-dos-Santos, Amanda Ferreira Vidal, Gilderlanio S. de Araújo, Samia Demachki, Ândrea Ribeiro-dos-Santos
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Mitochondria are organelles that perform major roles in cellular operation. Thus, alterations in mitochondrial genome (mtGenome) may lead to mitochondrial dysfunction and cellular deregulation, influencing carcinogenesis. Gastric cancer (GC)
Externí odkaz:
https://doaj.org/article/df2df62ae1ba4182bdb4cf847bb6e43b
Autor:
André M. Ribeiro-dos-Santos, Amanda Ferreira Vidal, Tatiana Vinasco-Sandoval, João Guerreiro, Sidney Santos, Ândrea Ribeiro-dos-Santos, Sandro J. de Souza
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Studies on the peopling of South America have been limited by the paucity of sequence data from Native Americans, especially from the east part of the Amazon region. Here, we investigate the whole exome variation from 58 Native American individuals (
Externí odkaz:
https://doaj.org/article/d750eb5631f042679cdf2c1b2b722803
Autor:
Juliana Carla Gomes Rodrigues, Tatiane Piedade de Souza, Lucas Favacho Pastana, André Maurício Ribeiro Dos Santos, Marianne Rodrigues Fernandes, Pablo Pinto, Alayde Vieira Wanderley, Sandro José de Souza, José Eduardo Kroll, Adenilson Leão Pereira, Leandro Magalhães, Laís Reis das Mercês, Amanda Ferreira Vidal, Tatiana Vinasco-Sandoval, Giovanna Chaves Cavalcante, João Farias Guerreiro, Paulo Pimentel de Assumpção, Ândrea Ribeiro-Dos-Santos, Sidney Santos, Ney Pereira Carneiro Dos Santos
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231651 (2020)
IntroductionThe nudix hydrolase 15 (NUDT15) gene acts in the metabolism of thiopurine, by catabolizing its active metabolite thioguanosine triphosphate into its inactivated form, thioguanosine monophosphate. The frequency of alternative NUDT15 allele
Externí odkaz:
https://doaj.org/article/80247432adae42ae8572c23f313d6aa1
Autor:
Leandro Magalhães, Luciana Gonçalves Quintana, Dielly Catrina Favacho Lopes, Amanda Ferreira Vidal, Adenilson Leão Pereira, Lara Carolina D’Araujo Pinto, João de Jesus Viana Pinheiro, André Salim Khayat, Luiz Ricardo Goulart, Rommel Burbano, Paulo Pimentel de Assumpção, Ândrea Ribeiro-dos-Santos
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Several genetic and epigenetic alterations are related to the development and progression of Gastric Cancer (GC), one of those being the deregulated microRNA (miRNA) expression profile. miRNAs are small noncoding RNAs that negativ
Externí odkaz:
https://doaj.org/article/51a8cf297aa24c65961be1e66e5106b6
Publikováno v:
Cells, Vol 10, Iss 6, p 1410 (2021)
Parkinson’s disease (PD) is the second-most common neurodegenerative disease, and its pathophysiology is associated with alpha-synuclein accumulation, oxidative stress, mitochondrial dysfunction, and neuroinflammation. MicroRNAs are small non-codin
Externí odkaz:
https://doaj.org/article/5ad05e63e3394682b9ac413ab01528ca
Autor:
Leonardo Miranda Brito, Ândrea Ribeiro-dos-Santos, Amanda Ferreira Vidal, Gilderlanio Santana de Araújo
Publikováno v:
Biology, Vol 9, Iss 9, p 251 (2020)
Mild cognitive impairment (MCI) and Alzheimer’s Disease (AD) are complex diseases with their molecular architecture not elucidated. APOE, Amyloid Beta Precursor Protein (APP), and Presenilin-1 (PSEN1) are well-known genes associated with both MCI a
Externí odkaz:
https://doaj.org/article/3b108baefa8341e1956aa59fc85493af
Autor:
Claudio Guedes Salgado, Pablo Pinto, Raquel Carvalho Bouth, Angélica Rita Gobbo, Ana Caroline Cunha Messias, Tatiana Vinasco Sandoval, André Mauricio Ribeiro dos Santos, Fabiano Cordeiro Moreira, Amanda Ferreira Vidal, Luiz Ricardo Goulart, Josafá Gonçalves Barreto, Moisés Batista da Silva, Marco Andrey Cipriani Frade, John Stewart Spencer, Sidney Santos, Ândrea Ribeiro-dos-Santos
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Leprosy remains as a public health problem and its physiopathology is still not fully understood. MicroRNAs (miRNA) are small RNA non-coding that can interfere with mRNA to regulate gene expression. A few studies using DNA chip microarrays have explo
Externí odkaz:
https://doaj.org/article/51330964b24442c7ba93024242a7b8f7
Autor:
Camille Sena-Dos-Santos, Ândrea Ribeiro-dos-Santos, Gleyce Fonseca Cabral, Jhully Azevedo Dos Santos Pinheiro, Natacha Medeiros de Souza Port's, Giovanna C Cavalcante, Amanda Ferreira Vidal, Ana Paula Schaan, Tatiane Piedade de Souza
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9839, p 9839 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 9839, p 9839 (2021)
Background: Parkinson’s disease (PD) is currently the second most common neurodegenerative disorder, burdening about 10 million elderly individuals worldwide. The multifactorial nature of PD poses a difficult obstacle for understanding the mechanis
Publikováno v:
Cells
Volume 10
Issue 6
Cells, Vol 10, Iss 1410, p 1410 (2021)
Volume 10
Issue 6
Cells, Vol 10, Iss 1410, p 1410 (2021)
Parkinson’s disease (PD) is the second-most common neurodegenerative disease, and its pathophysiology is associated with alpha-synuclein accumulation, oxidative stress, mitochondrial dysfunction, and neuroinflammation. MicroRNAs are small non-codin