Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amanda Ewan"'
Autor:
Mark Battle, Alessandra Gaeta, Dennis O'shea, Penny Hao Zheng, Julian Goggi, Stuart Plant, Benedicte Guilbert, Samantha L. Brown, Amanda Ewan, Paul A. Jones, John Woodcraft, Alexander Jackson, Denis Raymond Christophe Bouvet, William Trigg, Clare Jones
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:821-826
Positron emission tomography (PET) using the tracer [(11)C]Flumazenil has shown changes in the distribution and expression of the GABA(A) receptor in a range of neurological conditions and injury states. We aim to develop a fluorine-18 labelled PET a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9e22d05165f979ba2fdd7879552b82
https://doi.org/10.1016/j.bmcl.2012.11.066
https://doi.org/10.1016/j.bmcl.2012.11.066
Autor:
Wai-Fung Chau, Dimitrios Mantzilas, Naghmeh Fouladi, Mikkel Thaning, Paul A. Jones, William Trigg, Veronique Morisson-Iveson, Ingvil Gausemel, Clare Durrant, Imtiaz Khan, Andrew Black, Joanna Passmore, Michelle Avory, Dennis O'shea, Harry John Wadsworth, Amanda Ewan, Duncan Wynn
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1308-1313
A series of tricyclic compounds have been synthesised and evaluated in vitro for affinity against Translocator protein 18 kDa (TSPO) and for preferred imaging properties. The most promising of the compounds were radiolabelled and evaluated in vivo to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9f7aae2c6ef9e829fccfa42f32630ad
https://doi.org/10.1016/j.bmcl.2011.12.084
https://doi.org/10.1016/j.bmcl.2011.12.084
Autor:
Veronique Morisson-Iveson, Amanda Ewan, Sondre Nilsen, Joanna Passmore, Harry John Wadsworth, William Trigg, Mikkel Thaning
Publikováno v:
Tetrahedron Letters. 55:5141-5143
[18F]GE-180 has been demonstrated to be a promising new positron emission tomography radiotracer for targeting translocator protein. PET imaging of TSPO will enable measurement of neuroinflammation and microglia activity in vivo. The synthetic route
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfdc7f81d392cde00407bac438d33d76
https://doi.org/10.1016/j.tetlet.2014.07.090
https://doi.org/10.1016/j.tetlet.2014.07.090
Autor:
Dennis O'shea, Mark Battle, Wai-Fung Chau, William Trigg, Samantha L. Brown, Alexander Jackson, Paul A. Jones, Amanda Ewan, Alessandra Gaeta, Denis Raymond Christophe Bouvet, Benedicte Guilbert, Clare Jones, John Woodcraft
Publikováno v:
Nuclear medicine and biology. 41(2)
Introduction [ 11 C]Flumazenil has been used to study the GABA A receptor in many preclinical and clinical studies, but the short half-life of carbon-11 means that this molecule is restricted to use by investigators with access to on-site cyclotron a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad58dd58ab059e2180a1ffcdaaa9cee3
https://pubmed.ncbi.nlm.nih.gov/24480268
https://pubmed.ncbi.nlm.nih.gov/24480268
Autor:
Harry, Wadsworth, Paul A, Jones, Wai-Fung, Chau, Clare, Durrant, Naghmeh, Fouladi, Joanna, Passmore, Dennis, O'Shea, Duncan, Wynn, Veronique, Morisson-Iveson, Amanda, Ewan, Mikkel, Thaning, Dimitrios, Mantzilas, Ingvil, Gausemel, Imtiaz, Khan, Andrew, Black, Michelle, Avory, William, Trigg
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(3)
A series of tricyclic compounds have been synthesised and evaluated in vitro for affinity against Translocator protein 18 kDa (TSPO) and for preferred imaging properties. The most promising of the compounds were radiolabelled and evaluated in vivo to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1265dd2071e904eee4ac03f9e25dc25a
https://pubmed.ncbi.nlm.nih.gov/22244939
https://pubmed.ncbi.nlm.nih.gov/22244939
Autor:
Carys Jones
A missing husband. Mysterious calls. And the biggest lie of them all. Read with caution - you may never want to answer your phone again... Will and Amanda Thorne are living the dream until, one day, their phone rings. Within 24 hours, Will is missing
Autor:
Thomas, Polly
The Rough Guide to Trinidad and Tobago is the definitive guide to these high-spirited twin islands. White-sand beaches, swaying palms, and reef-studded waters are all here for the taking, but Trinidad and Tobago turn the Caribbean stereotype on its h
Autor:
Andrew Pollard, Pat Triggs
The result of a research project, this work, an attempt to report on what has actually been happening in our schools, answers such questions as: what difference have education reforms made to pupils'experience in schools? and how has recent education