Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amanda Engstrom"'
Autor:
Shyamala Maheswaran, Daniel A. Haber, Mehmet Toner, Sridhar Ramaswamy, Beverly Moy, David T. Ting, Ravi Kapur, Dennis Sgroi, Toshi Shioda, Olivia Mackenzie, Huili Zhu, Kira Niederhoffer, Valentine Comaills, Yu Zheng, Francesca Bersani, Amanda Engstrom, Ryan O'Keefe, Maria C. Donaldson, Ben S. Wittner, Aditya Bardia, Nicola Aceto
Supplementary Table S1: Patients and clinical information. Supplementary Table S2: Genes used to determine the AR signature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e33c08ccde0e98ddafd38db848965d
https://doi.org/10.1158/1541-7786.22513614.v1
https://doi.org/10.1158/1541-7786.22513614.v1
Autor:
Shyamala Maheswaran, Daniel A. Haber, Mehmet Toner, Sridhar Ramaswamy, Beverly Moy, David T. Ting, Ravi Kapur, Dennis Sgroi, Toshi Shioda, Olivia Mackenzie, Huili Zhu, Kira Niederhoffer, Valentine Comaills, Yu Zheng, Francesca Bersani, Amanda Engstrom, Ryan O'Keefe, Maria C. Donaldson, Ben S. Wittner, Aditya Bardia, Nicola Aceto
Supplementary Figure S1: RNA sequencing and pathway analysis of CTCs from Bone(+) versus Visceral(+) breast cancer patients. Supplementary Figure S2: Correlation between AR expression and AR signatures. Supplementary Figure S3: ER and PR expression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bcb22f6f41dd87c04574d8f01ab6e8
https://doi.org/10.1158/1541-7786.22513617.v1
https://doi.org/10.1158/1541-7786.22513617.v1
Autor:
Dennis C. Sgroi, Francesca Bersani, Daniel A. Haber, Huili Zhu, Olivia C. MacKenzie, Beverly Moy, Sridhar Ramaswamy, Toshi Shioda, Ryan M. O'Keefe, Amanda Engstrom, Nicola Aceto, Shyamala Maheswaran, Kira L. Niederhoffer, Maria C. Donaldson, Yu Zheng, Valentine Comaills, Ben S. Wittner, David T. Ting, Ravi Kapur, Aditya Bardia, Mehmet Toner
Molecular drivers underlying bone metastases in human cancer are not well understood, in part due to constraints in bone tissue sampling. Here, RNA sequencing was performed of circulating tumor cells (CTC) isolated from blood samples of women with me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7200061fc4d41c103ef9c3c27ff31e
http://hdl.handle.net/2318/1794754
http://hdl.handle.net/2318/1794754
Autor:
David T. Ting, A. Fatih Sarioglu, Ravi Kapur, Tilak K. Sundaresan, David T. Miyamoto, Amanda Engstrom, Shyamala Maheswaran, Nicola Aceto, Daniel A. Haber, Huili Zhu, Xi Luo, Toshi Shioda, Shannon L. Stott, Bashar Hamza, Mehmet Toner, Ben S. Wittner, Sridhar Ramaswamy, Mahnaz Zeinali, Maria C. Donaldson, Nikola Kojic, Aditya Bardia
Publikováno v:
Nature methods
Nature Methods
Nature Methods
Cancer cells metastasize through the bloodstream either as single migratory circulating tumor cells (CTCs) or as multicellular groupings (CTC-clusters). Existing technologies for CTC enrichment are designed primarily to isolate single CTCs, and while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18abb7c86e5e45d8a4140d27469a4ea
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490017/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490017/
Autor:
Min Yu, Toshi Shioda, Shyamala Maheswaran, Nicola Aceto, Adam Pely, Charles P. Lin, Joel A. Spencer, Mehmet Toner, Ben S. Wittner, Brian W. Brannigan, Maria C. Donaldson, Daniel A. Haber, Amanda Engstrom, Aditya Bardia, Huili Zhu, Shannon L. Stott, David T. Miyamoto, Sridhar Ramaswamy, David T. Ting, Ravi Kapur
Publikováno v:
Cell
SummaryCirculating tumor cell clusters (CTC clusters) are present in the blood of patients with cancer but their contribution to metastasis is not well defined. Using mouse models with tagged mammary tumors, we demonstrate that CTC clusters arise fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622e1bd24db0225b076528531d5d5039
Autor:
Xiaodong Cheng, Elizabeth L. Zoeller, Haian Fu, Xing Zhang, John R. Shanks, Paula M. Vertino, John R. Horton, Amanda Engstrom, Margaret A. Johns, Xu Liu
Publikováno v:
The Journal of biological chemistry. 291(6)
The KDM5/JARID1 family of Fe(II)- and α-ketoglutarate-dependent demethylases remove methyl groups from tri- and dimethylated lysine 4 of histone H3. Accumulating evidence from primary tumors and model systems supports a role for KDM5A (JARID1A/RBP2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50150d2d94cb42cf177330c63dceb43c
https://pubmed.ncbi.nlm.nih.gov/26645689
https://pubmed.ncbi.nlm.nih.gov/26645689
Autor:
Ken Tajima, Amanda Engstrom, Daniel A. Haber, Sarah Javaid, Johnathan R. Whetstine, Sridhar Ramaswamy, Shyamala Maheswaran, Oliver H. Tam, Toshifumi Yae, Fumiyuki Takahashi, Valentine Comaills, Ben S. Wittner, Molly Hammell, Joshua C. Black, Mingzhu Liu, Toshihiro Shioda, Robert Morris
Publikováno v:
Nature Communications
Expression of the p53-inducible antiproliferative gene BTG2 is suppressed in many cancers in the absence of inactivating gene mutations, suggesting alternative mechanisms of silencing. Using a shRNA screen targeting 43 histone lysine methyltransferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e074049dc7a974965a9e173ede1861cc
https://pubmed.ncbi.nlm.nih.gov/26394836
https://pubmed.ncbi.nlm.nih.gov/26394836
Autor:
Elizabeth M. Jaffee, Eric R. Lutz, Chan C. Whiting, Margit Cecile Tagliaferri, Amanda Engstrom, Dung T. Le, Ed Lemmens, Dirk G. Brockstedt, Nitya Nair, Aimee Murphy
Publikováno v:
Journal of Clinical Oncology. 34:459-459
459 Background: Baseline patient characteristics may impact duration on study and survivorship of patients in immunotherapy trials. In this study, GVAX pancreas (GM-CSF–secreting allogeneic pancreatic tumor cells) was administered with low-dose cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5a247ca413838bc224360b08ea2e9c6
https://doi.org/10.1200/jco.2016.34.4_suppl.459
https://doi.org/10.1200/jco.2016.34.4_suppl.459
Autor:
Amanda Engstrom, Daniel A. Haber, Huili Zhu, Shyamala Maheswaran, Shannon L. Stott, David T. Ting, Ravi Kapur, Ben S. Wittner, Min Yu, Brian W. Brannigan, Sridhar Ramaswamy, Adam Pely, Maria C. Donaldson, Nicola Aceto, Joel A. Spencer, Toshi Shioda, Charles P. Lin, Aditya Bardia, Mehmet Toner
Publikováno v:
Cancer Research. 74:LB-192
The metastatic spread of breast cancer, typically to bone, lung, liver and brain, accounts for the vast majority of cancer-related deaths. Breast cancer metastases are thought to be derived primarily from individual migratory cancer cells, reaching d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d6eecc9c8304560354160afa96bc2ee
https://doi.org/10.1158/1538-7445.am2014-lb-192
https://doi.org/10.1158/1538-7445.am2014-lb-192