Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Amanda Elton"'
Autor:
Cory N. Spencer, Amanda Elton, Samantha Dove, Monica L. Faulkner, Donita L. Robinson, Charlotte A. Boettiger
Publikováno v:
Addiction Neuroscience, Vol 7, Iss , Pp 100085- (2023)
The non-selective opioid receptor antagonist, naltrexone is one of the most prescribed medications for treating alcohol and opioid addiction. Despite decades of clinical use, the mechanism(s) by which naltrexone reduces addictive behavior remains unc
Externí odkaz:
https://doaj.org/article/b6cd0991404b491ba1fb5ef81e52fcc4
Autor:
Alexander Gómez-A, Carol A. Dannenhoffer, Amanda Elton, Sung-Ho Lee, Woomi Ban, Yen-Yu Ian Shih, Charlotte A. Boettiger, Donita L. Robinson
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Behavioral flexibility, the ability to modify behavior according to changing conditions, is essential to optimize decision-making. Deficits in behavioral flexibility that persist into adulthood are one consequence of adolescent alcohol exposure, and
Externí odkaz:
https://doaj.org/article/7304f24861974a359b8ff3c5171c669f
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Binge patterns of alcohol use among post-high school emerging adults are associated with both immediate negative consequences and increased risk of long-term drinking problems, particularly among individuals with a family history (FH) of alcohol use
Externí odkaz:
https://doaj.org/article/ffc37bf3b22047a5bb9bbaf8e5578ddc
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102801- (2021)
A family history of alcoholism (FH) increases risk for alcohol use disorder (AUD), yet many at-risk individuals never develop alcohol use problems. FH is associated with intermediate levels of risk phenotypes, whereas distinct, compensatory brain cha
Externí odkaz:
https://doaj.org/article/bc6f6f0da37b441db09ea94215aa929f
Autor:
Amanda Elton, Catherine Stanger, G. Andrew James, Stacy Ryan-Pettes, Alan Budney, Clinton D. Kilts
Publikováno v:
NeuroImage: Clinical, Vol 24, Iss , Pp - (2019)
Adolescent drug misuse represents a major risk factor for long-term drug use disorders. However, wide individual differences in responses to first-line behavioral therapies targeting adolescent drug misuse limit critical early intervention. Identifyi
Externí odkaz:
https://doaj.org/article/65cbf03815df4601b97387aa56e92d62
Publikováno v:
Frontiers in Human Neuroscience, Vol 11 (2017)
Evidence suggests that dopamine levels in the prefrontal cortex (PFC) modulate executive functions. A key regulator of PFC dopamine is catechol-O-methyltransferase (COMT). The activity level of the COMT enzyme are influenced by sex and the Val158Met
Externí odkaz:
https://doaj.org/article/b95ed83b653b4b87be7ce5181de088a6
Publikováno v:
Human Brain Mapping. 44:2436-2450
BackgroundChildhood maltreatment (CM) and a family history (FH) of alcohol use disorder (AUD) are each associated with increased impulsivity. However, their unique or shared brain targets remain unknown. Furthermore, both CM and FH demonstrate sex-de
Publikováno v:
Pharmacol Biochem Behav
The automatic capture of attention by drug cues, or attentional bias, is associated with craving and predicts future drug use. Despite its clinical significance, the neural bases of attentional bias to drug cues is not well understood. To address thi
Publikováno v:
Alcohol Clin Exp Res
Background Naltrexone, an opioid receptor antagonist that is Food and Drug Administration approved for treating alcohol use disorder (AUD), reduces alcohol craving and intake. Despite known pharmacological properties, little is known regarding the ef