Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Amanda E. Semper"'
Autor:
Aleš Chrdle, Pavlína Tinavská, Olga Dvořáčková, Pavlína Filipová, Věra Hnetilová, Pavel Žampach, Květoslava Batistová, Václav Chmelík, Amanda E. Semper, Nick J. Beeching
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 10, Pp 1919-1927 (2019)
We retrospectively assessed the utility of a flow cytometry–based test quantifying the percentage of CD3+ T cells with the CD4–/CD8– phenotype for predicting tularemia diagnoses in 64 probable and confirmed tularemia patients treated during 200
Externí odkaz:
https://doaj.org/article/1072aefc531c4b589d0824443b47bbbd
Autor:
Robert M Christley, Amanda E Semper, Tim J G Brooks, Katherine Russell, Kate D Halsby, Jenny C Warner
Publikováno v:
BMJ Open, Vol 9, Iss 8 (2019)
ObjectiveLyme disease is a tick-borne disease of increasing incidence and public concern across the Northern Hemisphere. However, the socio-demographics and geographic distribution of the population affected in England and Wales are poorly understood
Externí odkaz:
https://doaj.org/article/319901ee88dc4b34994f215701da82af
Autor:
Jennifer C Warner, Diane Hatziioanou, Jane C Osborne, Daniel J Bailey, Timothy J G Brooks, Amanda E Semper
Publikováno v:
Journal of Travel Medicine. 30
Background Every year, many thousands of travellers return to the United Kingdom (UK) from visits to other countries and some will become unwell due to infections acquired abroad. Many imported infections have similar clinical presentations, such as
Autor:
Amanda E Semper, M Jana Broadhurst, Jade Richards, Geraldine M Foster, Andrew J H Simpson, Christopher H Logue, J Daniel Kelly, Ann Miller, Tim J G Brooks, Megan Murray, Nira R Pollock
Publikováno v:
PLoS Medicine, Vol 13, Iss 3, p e1001980 (2016)
Throughout the Ebola virus disease (EVD) epidemic in West Africa, field laboratory testing for EVD has relied on complex, multi-step real-time reverse transcription PCR (RT-PCR) assays; an accurate sample-to-answer RT-PCR test would reduce time to re
Externí odkaz:
https://doaj.org/article/aa573f1f7f5a497a891c1ad3ffc93a4b
Autor:
Sara Lustigman, Sophie J. Barker, Shibo Jiang, Yuxian He, Ranjit Parhar, Amanda E. Semper, Douglas T. Golenbock, Susanne Hartmann, Yu Yu, Nathan A. Libri, Susanne Heck, Angus Macdonald, Jingjing Li, William Rosenberg, Long Cao
Publikováno v:
The Journal of Immunology. 182:4005-4016
We previously reported that rOv-ASP-1, a recombinant Onchocerca volvulus activation associated protein-1, was a potent adjuvant for recombinant protein or synthetic peptide-based Ags. In this study, we further evaluated the adjuvanticity of rOv-ASP-1
Autor:
Amanda E. Semper, Tamara Al-Bader, Judith A. Holloway, Peter S. Friedmann, Myron Christodoulides, Keith A. Jolley, Holly E. Humphries, John E. Heckels
Publikováno v:
Cellular Microbiology. 6:651-662
The major porin proteins present in the outer membrane of Neisseria meningitidis, the causative agent of life-threatening meningitis and septicaemia, are believed to have potent immunostimulatory effects. In this study, the interactions between human
Autor:
Jarema P. Kochan, Amanda E. Semper, Peter S. Friedmann, Alexander C. S. Woollard, Martin K. Church, Kyle Heron, Ilona G. Reischl
Publikováno v:
Journal of Allergy and Clinical Immunology. 112:411-419
Background: FcϵRI expressed on the surface of human epidermal Langerhans' cells facilitates uptake of IgE-associated allergens and plays a pivotal role in the pathogenesis of atopic dermatitis. Seminal results from studies investigating Langerhans'
Publikováno v:
Journal of Allergy and Clinical Immunology. 107:1009-1018
Background: Dendritic cells can express the high-affinity IgE receptor (FcϵRI), which, in the presence of specific IgE, facilitates the uptake of allergen, leading to increased activation of allergen-specific T cells. FcϵRI expression by dendritic
Autor:
Amanda E. Semper, Luis M. Teran, Anthony E. Redington, Anthony J. Frew, K.J. Bodey, S. T. Holgate, J. Madden
Publikováno v:
Allergy. 54:1083-1093
Background: This study assessed the heterogeneity of cytokine expression in asthma before and after local allergen challenge. Methods: BAL T cells were obtained 10 min or 24 h after local endobronchial allergen challenge in atopic asthmatic subjects.
Autor:
Martin K. Church, S. T. Holgate, J. A. Hartley, Amanda E. Semper, Peter Bradding, J. M. Tunon-De-Lara, Anthony E. Redington
Publikováno v:
Clinical & Experimental Allergy. 26:648-655
BACKGROUND: Immunoglobulin E (IgE) plays an important role in asthma, with total serum IgE levels closely related to both clinical expression of the disease and airway hyperresponsiveness. IgE binds to a high affinity cell-surface receptor (Fc epsilo