Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Amanda E Garza"'
Autor:
Isis Akemi Katayama, Yuefei Huang, Amanda E. Garza, Danielle L. Brooks, Jonathan S. Williams, Mariana M. Nascimento, Joel C. Heimann, Luminita H. Pojoga
Publikováno v:
Experimental Gerontology, Vol 173, Iss , Pp 112114- (2023)
Background: Dietary sodium is a well-known risk factor for cardiovascular and renal disease; however, direct evidence of the longitudinal changes that occur with aging, and the influence of dietary sodium on the age-associated alterations are scarce.
Externí odkaz:
https://doaj.org/article/29ed570a00834436b50e4c4d49da4fce
Autor:
Harry Kane, Nelson M LaMarche, Áine Ní Scannail, Amanda E Garza, Hui-Fern Koay, Adiba I Azad, Britta Kunkemoeller, Brenneth Stevens, Michael B Brenner, Lydia Lynch
Publikováno v:
eLife, Vol 11 (2022)
Innate T cells, including CD1d-restricted invariant natural killer T (iNKT) cells, are characterized by their rapid activation in response to non-peptide antigens, such as lipids. While the transcriptional profiles of naive, effector, and memory adap
Externí odkaz:
https://doaj.org/article/13c9d127f6404c0f9e370cc5ce5f8c3b
Autor:
Amanda E Garza, Gordon H. Williams, Luminita H. Pojoga, Chee Sin Tay, Jian Yao Wong, Shadi K Gholami, Jose R. Romero, Ezgi Caliskan Guzelce, Jessica Lee, Gail K. Adler, Eleanor Zagoren, Stephen A. Maris
Publikováno v:
Journal of Endocrinology. 252:1-13
Inconsistencies have been reported on the effect of sex on aldosterone (ALDO) levels leading to clinical confusion. The reasons for these inconsistencies are uncertain but include estrogen and/or its receptor modulating target gene responses to miner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e03fdd389bb0040a4c3b8023458165
https://doi.org/10.1530/joe-21-0126
https://doi.org/10.1530/joe-21-0126
Autor:
Gail K. Adler, Joshua J. Man, Marina Anastasiou, M. Elizabeth Moss, Brigett Carvajal, Pilar Alcaide, Roy Freeman, Qing Lu, Njabulo Ngwenyama, Wendy Baur, Iris Z. Jaffe, Amanda E Garza
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: MR (mineralocorticoid receptor) activation associates with increased risk of cardiovascular ischemia while MR inhibition reduces cardiovascular-related mortality and plaque inflammation in mouse atherosclerosis. MR in myeloid cells (My-MR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488ed40a31df83d26f735110a8a09ef4
https://doi.org/10.1161/atvbaha.121.316929
https://doi.org/10.1161/atvbaha.121.316929
Autor:
Harry Kane, Nelson M LaMarche, Áine Ní Scannail, Amanda E Garza, Hui-Fern Koay, Adiba I Azad, Britta Kunkemoeller, Brenneth Stevens, Michael B Brenner, Lydia Lynch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a3a035ac6465ad803f880a190f12fb
https://doi.org/10.7554/elife.76586.sa2
https://doi.org/10.7554/elife.76586.sa2
Autor:
Rene Baudrand, Nidhi Gupta, Amanda E. Garza, Anand Vaidya, Jane A. Leopold, Paul N. Hopkins, Xavier Jeunemaitre, Claudio Ferri, Jose R. Romero, Jonathan Williams, Joseph Loscalzo, Gail K. Adler, Gordon H. Williams, Luminita H. Pojoga
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 10 (2016)
BackgroundOveractivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associated with hyperglycemia and dyslipidemia. Caveolin 1 (cav‐1) is involved in glucose/lipid homeostasis and may modulate MR signaling. We investigated th
Externí odkaz:
https://doaj.org/article/a7ed1ec70b2b4a6b8a2e50760751ff45
Autor:
Burhanuddin Moize, Elijah Trefts, Tham M. Yao, Rene Baudrand, Sanjay Ranjit, Gail K. Adler, Thitinan Treesaranuwattana, Isis Katayama Rangel, Luminita H. Pojoga, Amanda E Garza, Jose R. Romero, Gordon H. Williams, Danielle L Brooks
Publikováno v:
The Journal of Endocrinology
Aldosterone modulates the activity of both epithelial (specifically renal) and non-epithelial cells. Binding to the mineralocorticoid receptor (MR), activates two pathways: the classical genomic and the rapidly activated non-genomic that is substanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3be07f37df81e640130b7d0d5e8bad
https://doi.org/10.1530/joe-19-0562
https://doi.org/10.1530/joe-19-0562
Autor:
Amanda E Garza, Luminita H. Pojoga, Gail K. Adler, Danielle L Brooks, Jose R. Romero, Isis Akemi Katayama, Gordon H. Williams
Publikováno v:
Endocrinology. 160:716-728
Both mechanistic target of rapamycin (mTOR) pathway and aldosterone are implicated in the development of cardiovascular and renal disease. However, the interaction between aldosterone and the mTOR pathway is unknown. We hypothesized the following: th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4120c1912a9f0832b1a8ccc88a05b99c
https://doi.org/10.1210/en.2018-00989
https://doi.org/10.1210/en.2018-00989
Autor:
Stephen A. Maris, Jessica Lee, Shadi K Gholami, Gordon H. Williams, Thitinan Treesaranuwattana, Chee Sin Tay, Danielle L Brooks, Sanjay Ranjit, Gail K. Adler, Luminita H. Pojoga, Jose R. Romero, Amanda E Garza, Ezgi Caliskan Guzelce
Publikováno v:
Endocrinology
The mechanistic target of the rapamycin (mTOR) pathway plays a role in features common to both excess salt/aldosterone and cardiovascular/renal diseases. Dietary sodium can upregulate mTORC1 signaling in cardiac and renal tissue, and the inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b65a1524358bd69ef07e453602866e4
Autor:
Jose R. Romero, Jia Wei Tan, Pei Yee Ting, Jonathan S. Williams, Paul N. Hopkins, Noha Ahmed, Amanda E Garza, Molly Connors, Tina Gupta, Worapaka Manosroi, Gordon H. Williams
Publikováno v:
American Journal of Hypertension. 31:124-131
BACKGROUND Understanding the interactions between genetics, sodium (Na+) intake, and blood pressure (BP) will help overcome the lack of individual specificity in our current treatment of hypertension. This study had 3 goals: expand on the relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d914533784ab28a100985bb620ed2d21
https://doi.org/10.1093/ajh/hpx146
https://doi.org/10.1093/ajh/hpx146